PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SapurV1A.0058s0640.1.p
Organism
Salix purpurea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Salix
Family bHLH
Protein Properties Length: 413aa    MW: 46662.6 Da    PI: 5.0362
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SapurV1A.0058s0640.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH38.91.6e-12213264155
                             CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
                     HLH   1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                             +r++h ++Er+RR+++N+ +  Lr+l+P +   + ++ + a+i   A+e++++L+
  SapurV1A.0058s0640.1.p 213 QRMTHIAVERNRRKQMNDHLRVLRSLMPGS---YVQRGDQASIIGGAIEFVRELE 264
                             79****************************...9*****************9995 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:4.10.280.101.7E-13211267IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.93E-12211268No hitNo description
SuperFamilySSF474599.16E-17212285IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088815.389212263IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000107.3E-10213264IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.2E-9218269IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF550215.84E-5338401No hitNo description
CDDcd048738.08E-4338402No hitNo description
PROSITE profilePS516719.224338412IPR002912ACT domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010377Biological Processguard cell fate commitment
GO:0045597Biological Processpositive regulation of cell differentiation
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051782Biological Processnegative regulation of cell division
GO:0005634Cellular Componentnucleus
GO:0016597Molecular Functionamino acid binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 413 aa     Download sequence    Send to blast
MLVCSELNFS QGSFTGLDNY SLDHHRQQEQ DHLGVLMKQR IGETSGDDDC NNGMIDYMLH  60
NPQQQMSSGF CTSSSFDKLS FADVMQFADF GPKLALNQNR ISEEGTGIDP VYFLKFPVLN  120
DKIDEHSIRV PQLGGENIEE MLKGESSEEH RAGMVGEERG IRENEEARIS DNNSVQLQFL  180
GDQDLQNNNP MPEGKNKRKR PRTIKTSEEV ESQRMTHIAV ERNRRKQMND HLRVLRSLMP  240
GSYVQRGDQA SIIGGAIEFV RELEQLLQCL ESQKRRRLME DSSLAIQQPA QPAFFPPMPL  300
PNDQMKLVDF ETGLREETAE NKSCLADVEV KLLGFDAMIK ILSRRRPGQL IKAIAALEDL  360
QLNILHTNIT TIDQTVLYSF NVKIASDSRF TAENIASSVQ QIFNFIHANS SI*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1213224RMTHIAVERNRR
2273277KRRRL
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956). {ECO:0000269|PubMed:17088607, ECO:0000269|PubMed:17183265, ECO:0000269|PubMed:17183267, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapSapurV1A.0058s0640.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Inhibited by low relative humidity (LRH) via epigenetic CG methylation, thus leading to a reduced stomatal index. {ECO:0000269|PubMed:22442411}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011045658.10.0PREDICTED: transcription factor FAMA isoform X1
SwissprotQ56YJ81e-144FAMA_ARATH; Transcription factor FAMA
TrEMBLB9GFX70.0B9GFX7_POPTR; Uncharacterized protein
STRINGPOPTR_0001s32160.10.0(Populus trichocarpa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF104893340
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G24140.11e-134bHLH family protein
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Matos JL, et al.
    Irreversible fate commitment in the Arabidopsis stomatal lineage requires a FAMA and RETINOBLASTOMA-RELATED module.
    Elife, 2015.
    [PMID:25303364]
  3. Chen L, et al.
    NRPB3, the third largest subunit of RNA polymerase II, is essential for stomatal patterning and differentiation in Arabidopsis.
    Development, 2016. 143(9): p. 1600-11
    [PMID:26989174]
  4. Lee JH,Jung JH,Park CM
    Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce Stomatal Development in Arabidopsis.
    Plant Cell, 2017. 29(11): p. 2817-2830
    [PMID:29070509]
  5. Han X, et al.
    Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons.
    Plant Physiol., 2018. 176(4): p. 2871-2885
    [PMID:29496884]
  6. Li X,Yang R,Chen H
    The Arabidopsis thaliana Mediator subunit MED8 regulates plant immunity to Botrytis Cinerea through interacting with the basic helix-loop-helix (bHLH) transcription factor FAMA.
    PLoS ONE, 2018. 13(3): p. e0193458
    [PMID:29513733]