PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00025757-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

NAC

Protein Properties

Length: 402aa MW: 44989.8 Da PI: 5.0535

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00025757-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	168.7	1.9e-52	32	159	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvkaeekewyfFskrdkkyatgkrknratksgyWkat 86 l+pGfrFhPtdeelv +yL++kv gk++++ ++++e+d+yk+ePw+L + ++k+++ ewyfFs+ d+ky +g+r nrat +gyWkat SMil_00025757-RA_Salv 32 LAPGFRFHPTDEELVRYYLRRKVCGKPFRF-QAVTEIDVYKSEPWELAEysSLKTRDLEWYFFSPVDRKYGNGSRLNRATGKGYWKAT 118 579***********************99.88**********84346777888************************** PP NAM 87 gkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 gkd++v + k++ +g+kktLvf++grap+g++t+Wvmheyrl SMil_00025757-RA_Salv 119 GKDRSVRH-KNQSIGMKKTLVFHSGRAPDGKRTNWVMHEYRL 159 ****.8999*************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	6.15E-62	29	182	IPR003441	NAC domain
PROSITE profile	PS51005	57.892	32	182	IPR003441	NAC domain
Pfam	PF02365	1.9E-28	34	159	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 402 aa Download sequence Send to blast
LGMEMGQEVV VAAVGSSAAP SPRMGAPPPT SLAPGFRFHP TDEELVRYYL RRKVCGKPFR 60 FQAVTEIDVY KSEPWELAEY SSLKTRDLEW YFFSPVDRKY GNGSRLNRAT GKGYWKATGK 120 DRSVRHKNQS IGMKKTLVFH SGRAPDGKRT NWVMHEYRLC DSELETAGIL QDAFVLCRIF 180 QKSGLGPPNG DRYAPFIEEE WDEDAPLVIP GGDVEDDVAN GDEVRGECMD LDQDTQPLSI 240 APPLVKYPVE STCIPFLCKR ERAAVDPEPL SLDHSKRSKH DDPNSSNANG SEDSTTTSQD 300 PSSMMMMTKI NSSPLEFPLL ETLGSKDNLP ANAPTFDSAN LEKSVPPGYL KFISNLENEI 360 LNISMEKETL KIEVMRAQAM INILQSRVES LTKENEDCRR RA

Sequence ? help Back to Top

Protein Sequence Length: 402 aa Download sequence Send to blast

LGMEMGQEVV VAAVGSSAAP SPRMGAPPPT SLAPGFRFHP TDEELVRYYL RRKVCGKPFR  60
FQAVTEIDVY KSEPWELAEY SSLKTRDLEW YFFSPVDRKY GNGSRLNRAT GKGYWKATGK  120
DRSVRHKNQS IGMKKTLVFH SGRAPDGKRT NWVMHEYRLC DSELETAGIL QDAFVLCRIF  180
QKSGLGPPNG DRYAPFIEEE WDEDAPLVIP GGDVEDDVAN GDEVRGECMD LDQDTQPLSI  240
APPLVKYPVE STCIPFLCKR ERAAVDPEPL SLDHSKRSKH DDPNSSNANG SEDSTTTSQD  300
PSSMMMMTKI NSSPLEFPLL ETLGSKDNLP ANAPTFDSAN LEKSVPPGYL KFISNLENEI  360
LNISMEKETL KIEVMRAQAM INILQSRVES LTKENEDCRR RA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	4e-51	31	182	16	165	NO APICAL MERISTEM PROTEIN
1ut4_B	4e-51	31	182	16	165	NO APICAL MERISTEM PROTEIN
1ut7_A	4e-51	31	182	16	165	NO APICAL MERISTEM PROTEIN
1ut7_B	4e-51	31	182	16	165	NO APICAL MERISTEM PROTEIN
3swm_A	4e-51	31	182	19	168	NAC domain-containing protein 19
3swm_B	4e-51	31	182	19	168	NAC domain-containing protein 19
3swm_C	4e-51	31	182	19	168	NAC domain-containing protein 19
3swm_D	4e-51	31	182	19	168	NAC domain-containing protein 19
3swp_A	4e-51	31	182	19	168	NAC domain-containing protein 19
3swp_B	4e-51	31	182	19	168	NAC domain-containing protein 19
3swp_C	4e-51	31	182	19	168	NAC domain-containing protein 19
3swp_D	4e-51	31	182	19	168	NAC domain-containing protein 19
4dul_A	4e-51	31	182	16	165	NAC domain-containing protein 19
4dul_B	4e-51	31	182	16	165	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC051/NAC052 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). {ECO:0000269\|PubMed:24045019, ECO:0000269\|PubMed:25578968, ECO:0000269\|PubMed:26617990}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011101542.1	0.0	NAC domain-containing protein 78 isoform X2
Swissprot	Q9SQX9	1e-113	NAC50_ARATH; NAC domain containing protein 50
TrEMBL	A0A2G9GMA1	0.0	A0A2G9GMA1_9LAMI; Uncharacterized protein
STRING	XP_009619467.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA3140	24	48

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10480.2	1e-112	NAC domain containing protein 50

Publications ? help Back to Top
Zhang S, et al. C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association. Cell Discov, 2019. [PMID:26617990]