PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00022804-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

NAC

Protein Properties

Length: 297aa MW: 33719.8 Da PI: 7.1641

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00022804-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	179.8	7.1e-56	16	141	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgk 88 lppGfrFhPtdeelv++yL +kv ++++++ ++i evd++kvePwdLp k+k +ekewyfF+ rd+ky+tg+r+nrat++gyWkatgk SMil_00022804-RA_Salv 16 LPPGFRFHPTDEELVSHYLSPKVLDRNFST-KAIGEVDLNKVEPWDLPWKAKIGEKEWYFFFLRDRKYPTGSRTNRATSAGYWKATGK 102 79************************99.88***********98999******************************* PP NAM 89 dkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 dke+++ ++ lvg+kktLvfy+grapkg+k++Wvmheyrl SMil_00022804-RA_Salv 103 DKEIFR-GQILVGMKKTLVFYRGRAPKGVKSNWVMHEYRL 141 **.99***************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.96E-63	11	165	IPR003441	NAC domain
PROSITE profile	PS51005	59.963	16	165	IPR003441	NAC domain
Pfam	PF02365	2.1E-28	17	141	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 297 aa Download sequence Send to blast
MEGSYSYDRS DEPIELPPGF RFHPTDEELV SHYLSPKVLD RNFSTKAIGE VDLNKVEPWD 60 LPWKAKIGEK EWYFFFLRDR KYPTGSRTNR ATSAGYWKAT GKDKEIFRGQ ILVGMKKTLV 120 FYRGRAPKGV KSNWVMHEYR LQGKGSNIFS TASKNEWVIC RVFKKGSGGS KVHISGPLSS 180 GDSCLDLPSL IDLSSGENTT NAAARGSHVT CFSNLIQDQQ DTSVDKFTSS SNMNFLDPRI 240 EDLHCPDSIS KQEQTTLHRL CRTNSSYMKQ YAATDFDDED ISIISSGQIE LDFLWNY

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3swm_A	5e-56	14	171	18	174	NAC domain-containing protein 19
3swm_B	5e-56	14	171	18	174	NAC domain-containing protein 19
3swm_C	5e-56	14	171	18	174	NAC domain-containing protein 19
3swm_D	5e-56	14	171	18	174	NAC domain-containing protein 19
3swp_A	5e-56	14	171	18	174	NAC domain-containing protein 19
3swp_B	5e-56	14	171	18	174	NAC domain-containing protein 19
3swp_C	5e-56	14	171	18	174	NAC domain-containing protein 19
3swp_D	5e-56	14	171	18	174	NAC domain-containing protein 19
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Functional Description ? help Back to Top
Source	Description
UniProt	Binds to the promoter regions of genes involved in chlorophyll catabolic processes, such as NYC1, SGR1, SGR2 and PAO. {ECO:0000269\|PubMed:27021284}.
UniProt	Transcription activator that binds to DNA in promoters of target genes on a specific bipartite motif 5'-[ACG][CA]GT[AG](5-6n)[CT]AC[AG]-3' (PubMed:23340744). Promotes lateral root development (PubMed:16359384). Triggers the expression of senescence-associated genes during age-, salt- and dark-induced senescence through a regulatory network that may involve cross-talk with salt- and H(2)O(2)-dependent signaling pathways (PubMed:9351240, PubMed:15295076, PubMed:20113437, PubMed:21303842). Regulates also genes during seed germination (PubMed:20113437). Regulates positively aging-induced cell death (PubMed:19229035). Involved in age-related resistance (ARR) against Pseudomonas syringae pv. tomato and Hyaloperonospora arabidopsidis (PubMed:19694953). Antagonizes GLK1 and GLK2 transcriptional activity, shifting the balance from chloroplast maintenance towards deterioration during leaf senescence (PubMed:23459204). Promotes the expression of senescence-associated genes, including ENDO1/BFN1, SWEET15/SAG29 and SINA1/At3g13672, during senescence onset (PubMed:23340744). {ECO:0000269\|PubMed:15295076, ECO:0000269\|PubMed:16359384, ECO:0000269\|PubMed:19229035, ECO:0000269\|PubMed:19694953, ECO:0000269\|PubMed:20113437, ECO:0000269\|PubMed:21303842, ECO:0000269\|PubMed:23340744, ECO:0000269\|PubMed:23459204, ECO:0000269\|PubMed:9351240}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: High levels during senescence (e.g. age-, salt- and dark-related) (PubMed:19229035, PubMed:20113437, PubMed:21511905, PubMed:22930749). By salt stress in an ethylene- and auxin-dependent manner (PubMed:16359384, PubMed:19608714, PubMed:20113437, PubMed:20404534). Induced by H(2)O(2) (PubMed:20404534). Accumulates in response to abscisic acid (ABA), ethylene (ACC) and auxin (NAA) (PubMed:16359384, PubMed:19608714). Repressed by high auxin (IAA) levels (PubMed:21511905). Age-related resistance (ARR)-associated accumulation (PubMed:19694953). Repressed by miR164 (PubMed:19229035). {ECO:0000269\|PubMed:16359384, ECO:0000269\|PubMed:19229035, ECO:0000269\|PubMed:19608714, ECO:0000269\|PubMed:19694953, ECO:0000269\|PubMed:20113437, ECO:0000269\|PubMed:20404534, ECO:0000269\|PubMed:21511905, ECO:0000269\|PubMed:22930749}.
UniProt	INDUCTION: Repressed by the microRNA miR164. {ECO:0000269\|PubMed:15294871, ECO:0000269\|PubMed:17098808}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011085744.1	1e-126	NAC domain-containing protein 100
Swissprot	Q9FKA0	1e-100	NAC92_ARATH; NAC domain-containing protein 92
Swissprot	Q9FLJ2	2e-99	NC100_ARATH; NAC domain-containing protein 100
TrEMBL	A0A2G9GGL5	1e-124	A0A2G9GGL5_9LAMI; Uncharacterized protein
STRING	Migut.H00942.1.p	1e-111	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA152	24	279

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G61430.1	1e-100	NAC domain containing protein 100

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Manacorda CA, et al. Salicylic acid determines differential senescence produced by two Turnip mosaic virus strains involving reactive oxygen species and early transcriptomic changes. Mol. Plant Microbe Interact., 2013. 26(12): p. 1486-98 [PMID:23945002] Khan M,Rozhon W,Poppenberger B The role of hormones in the aging of plants - a mini-review. Gerontology, 2014. 60(1): p. 49-55 [PMID:24135638] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Bohner A,Kojima S,Hajirezaei M,Melzer M,von Wirén N Urea retranslocation from senescing Arabidopsis leaves is promoted by DUR3-mediated urea retrieval from leaf apoplast. Plant J., 2015. 81(3): p. 377-87 [PMID:25440717] Sakuraba Y,Bülbül S,Piao W,Choi G,Paek NC Arabidopsis EARLY FLOWERING3 increases salt tolerance by suppressing salt stress response pathways. Plant J., 2017. 92(6): p. 1106-1120 [PMID:29032592] Kim H, et al. Circadian control of ORE1 by PRR9 positively regulates leaf senescence in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2018. 115(33): p. 8448-8453 [PMID:30065116]