PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00019240-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

HSF

Protein Properties

Length: 302aa MW: 34806.4 Da PI: 8.2418

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00019240-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	111.8	4.8e-35	42	134	2	103
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkg 89 Fl+k+y+++ede++ e++sws+ +nsf+v+d+++fa ++Lpk+Fkh+nf+SFvRQLn+YgF+kv+ ++ weF+++ F +g SMil_00019240-RA_Salv 42 FLSKTYDLVEDESTIEIVSWSRGNNSFIVWDPHKFAINLLPKFFKHNNFSSFVRQLNTYGFRKVDPDK---------WEFANEGFLRG 120 9**************************************************************999.........******* PP XXXXXXXXXXXXXX CS HSF_DNA-bind 90 kkellekikrkkse 103 +k+ll++i+r++++ SMil_00019240-RA_Salv 121 QKHLLKNIRRRRTS 134 ********9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46785	1.77E-34	38	131	IPR011991	Winged helix-turn-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	1.1E-37	38	131	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	3.7E-59	38	131	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	6.9E-31	42	131	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	9.7E-19	42	65	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	9.7E-19	80	92	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	81	105	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	9.7E-19	93	105	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 302 aa Download sequence Send to blast
MNIIGSMKEE FLGSSSLELD VGRGYNNPQA MEGLHEAGPP PFLSKTYDLV EDESTIEIVS 60 WSRGNNSFIV WDPHKFAINL LPKFFKHNNF SSFVRQLNTY GFRKVDPDKW EFANEGFLRG 120 QKHLLKNIRR RRTSSSNPVS CNNLESCVEV GRFGLEAEVD RLRRDKQVLV AELVKLRQQQ 180 QNTKAYLQAM EQRLKGTEQK QQQAMSFLAR AIRNPDFLQQ IVQHKEMKRE IEEAIGKKRR 240 KKIDHQELVG RMGHVAPRQW LDFGADEQGF WEGLMSEGVI DGDDEGVDVL ARQLGFLDSN 300 PR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ldu_A	1e-26	37	136	12	125	Heat shock factor protein 1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	118	131	RGQKHLLKNIRRRR
2	236	240	KKRRK
3	236	241	KKRRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
UniProt	Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE). {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00371	DAP	Transfer from AT3G22830	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat stress. {ECO:0000269\|PubMed:18064488}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011073463.1	1e-130	heat stress transcription factor A-6b-like
Swissprot	Q6VBB2	1e-110	HFA2B_ORYSJ; Heat stress transcription factor A-2b
Swissprot	Q9LUH8	1e-110	HFA6B_ARATH; Heat stress transcription factor A-6b
TrEMBL	A0A1R3I4V3	1e-125	A0A1R3I4V3_COCAP; Heat shock factor (HSF)-type, DNA-binding protein
STRING	cassava4.1_029306m	1e-121	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA572	24	113

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G22830.1	1e-112	heat shock transcription factor A6B

Publications ? help Back to Top
Rezaei MK,Shobbar ZS,Shahbazi M,Abedini R,Zare S Glutathione S-transferase (GST) family in barley: identification of members, enzyme activity, and gene expression pattern. J. Plant Physiol., 2013. 170(14): p. 1277-84 [PMID:23664583]