PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00010793-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

NAC

Protein Properties

Length: 410aa MW: 46116 Da PI: 5.0629

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00010793-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	164.2	4.7e-51	44	171	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkat 86 l+pGfrFhPtdeelv +yL++k+ gk++++ +++ e+d+yk+ePw+L +++k+++ ewyfFs+ d+ky +g+r nrat +gyWkat SMil_00010793-RA_Salv 44 LAPGFRFHPTDEELVRYYLRRKACGKPFRF-QAVIEIDVYKSEPWELAdySSLKTRDLEWYFFSPVDRKYGNGSRLNRATGKGYWKAT 130 579************************9.77999*******84347777888************************** PP NAM 87 gkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 gkd++v + k+ ++g+kktLvf++grap+g++t+Wvmheyrl SMil_00010793-RA_Salv 131 GKDRAVRH-KNLTIGMKKTLVFHSGRAPDGKRTNWVMHEYRL 171 ****.8899*************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	3.4E-62	41	194	IPR003441	NAC domain
PROSITE profile	PS51005	57.352	44	194	IPR003441	NAC domain
Pfam	PF02365	4.4E-28	46	171	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009555	Biological Process	pollen development
GO:0010228	Biological Process	vegetative to reproductive phase transition of meristem
GO:0005730	Cellular Component	nucleolus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 410 aa Download sequence Send to blast
LLLLFFFSFF FVVVGGSGEF RCWKMGQEVA VVGTAAGAPP PTSLAPGFRF HPTDEELVRY 60 YLRRKACGKP FRFQAVIEID VYKSEPWELA DYSSLKTRDL EWYFFSPVDR KYGNGSRLNR 120 ATGKGYWKAT GKDRAVRHKN LTIGMKKTLV FHSGRAPDGK RTNWVMHEYR LCDSELERAG 180 VTQDAFVLCR IFQKSGLGPP NGDRYAPFVE EEWDEDAVVV VPGGDAEDDV ANGDDARVEC 240 TDLDQETPPL SMAPPQVENT TGTQSLTFMC KRERSEEPEP LSLAQSKRGK AENPNSSHAN 300 GSEDSTTTSQ DPCTMMMTTN FTSGLLEFPL LEPKENQPGS TLTFDSSNLE KSVPPGYLKF 360 ISNLENEILN VSMERETLKI EVMRAQAMIN ILQSRVELVT KENEELRRRA

Sequence ? help Back to Top

Protein Sequence Length: 410 aa Download sequence Send to blast

LLLLFFFSFF FVVVGGSGEF RCWKMGQEVA VVGTAAGAPP PTSLAPGFRF HPTDEELVRY  60
YLRRKACGKP FRFQAVIEID VYKSEPWELA DYSSLKTRDL EWYFFSPVDR KYGNGSRLNR  120
ATGKGYWKAT GKDRAVRHKN LTIGMKKTLV FHSGRAPDGK RTNWVMHEYR LCDSELERAG  180
VTQDAFVLCR IFQKSGLGPP NGDRYAPFVE EEWDEDAVVV VPGGDAEDDV ANGDDARVEC  240
TDLDQETPPL SMAPPQVENT TGTQSLTFMC KRERSEEPEP LSLAQSKRGK AENPNSSHAN  300
GSEDSTTTSQ DPCTMMMTTN FTSGLLEFPL LEPKENQPGS TLTFDSSNLE KSVPPGYLKF  360
ISNLENEILN VSMERETLKI EVMRAQAMIN ILQSRVELVT KENEELRRRA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	4e-51	43	194	16	165	NO APICAL MERISTEM PROTEIN
1ut4_B	4e-51	43	194	16	165	NO APICAL MERISTEM PROTEIN
1ut7_A	4e-51	43	194	16	165	NO APICAL MERISTEM PROTEIN
1ut7_B	4e-51	43	194	16	165	NO APICAL MERISTEM PROTEIN
3swm_A	4e-51	43	194	19	168	NAC domain-containing protein 19
3swm_B	4e-51	43	194	19	168	NAC domain-containing protein 19
3swm_C	4e-51	43	194	19	168	NAC domain-containing protein 19
3swm_D	4e-51	43	194	19	168	NAC domain-containing protein 19
3swp_A	4e-51	43	194	19	168	NAC domain-containing protein 19
3swp_B	4e-51	43	194	19	168	NAC domain-containing protein 19
3swp_C	4e-51	43	194	19	168	NAC domain-containing protein 19
3swp_D	4e-51	43	194	19	168	NAC domain-containing protein 19
4dul_A	4e-51	43	194	16	165	NAC domain-containing protein 19
4dul_B	4e-51	43	194	16	165	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC050 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). Regulates siRNA-dependent post-transcriptional gene silencing (PTGS) through SGS3 expression modulation (PubMed:28207953). Required during pollen development (PubMed:19237690). {ECO:0000269\|PubMed:19237690, ECO:0000269\|PubMed:24045019, ECO:0000269\|PubMed:25578968, ECO:0000269\|PubMed:26617990, ECO:0000269\|PubMed:28207953}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00612	ChIP-seq	Transfer from AT3G10490	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by type III effector proteins (TTEs) secreted by the pathogenic bacteria P.syringae pv. tomato DC3000 during basal defense. {ECO:0000269\|PubMed:16553893}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011101542.1	0.0	NAC domain-containing protein 78 isoform X2
Swissprot	Q9SQY0	1e-113	NAC52_ARATH; NAC domain containing protein 52
TrEMBL	A0A2U5FKN3	0.0	A0A2U5FKN3_SALMI; NAC domain containing protein 2
STRING	XP_009619467.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA3140	24	48

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10480.2	1e-106	NAC domain containing protein 50

Publications ? help Back to Top
Higgins JD,Ferdous M,Osman K,Franklin FC The RecQ helicase AtRECQ4A is required to remove inter-chromosomal telomeric connections that arise during meiotic recombination in Arabidopsis. Plant J., 2011. 65(3): p. 492-502 [PMID:21265901] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zhang S, et al. C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association. Cell Discov, 2019. [PMID:26617990] Butel N,Le Masson I,Bouteiller N,Vaucheret H,Elmayan T sgs1: a neomorphic nac52 allele impairing post-transcriptional gene silencing through SGS3 downregulation. Plant J., 2017. 90(3): p. 505-519 [PMID:28207953] Elmayan T, et al. Arabidopsis mutants impaired in cosuppression. Plant Cell, 1998. 10(10): p. 1747-58 [PMID:9761800]