PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

TALE

Protein Properties

Length: 408aa MW: 45710.3 Da PI: 6.3654

Description

TALE family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00008976-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	25.5	2.2e-08	327	364	19	54
HHH..SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHH CS Homeobox 19 Fek..nrypsaeereeLAkklgLterqVkvWFqNrRak 54 F++ ++yp+ +e+ LA k gLt +qV++WF N R + SMil_00008976-RA_Salv 327 FHNflHPYPKDAEKHLLALKSGLTRSQVSNWFINARVR 364 776679******************************88 PP
2	BELL	70.2	3.7e-23	200	269	2	72
BELL 2 rqelqkkkakLlslleeVdkrYkqyveqlqtvissFeavaglgsakpYtslAlkaiSrhFrcLkdaiaeqi 72 ++e+++kk +L+sll+ Vd++Y+q+ ++++tv+s+F+ v+++++ ++++++Al ++S +r L+++i+ +i SMil_00008976-RA_Salv 200 EMEIESKKRHLMSLLQVVDDQYNQCLDEIHTVVSAFHSVTEVDP-ALHARFALPTVSVMYRDLRERISRHI 269 5799**************************************.79*******************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51257	5	1	28	No hit	No description
SMART	SM00574	4.3E-19	138	267	IPR006563	POX domain
Pfam	PF07526	4.6E-24	149	266	IPR006563	POX domain
SMART	SM00389	2.4E-5	308	372	IPR001356	Homeobox domain
CDD	cd00086	1.34E-11	308	369	No hit	No description
SuperFamily	SSF46689	3.25E-15	310	377	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	2.3E-25	311	374	IPR009057	Homeodomain-like
Pfam	PF05920	2.6E-14	325	364	IPR008422	Homeobox KN domain
PROSITE profile	PS50071	10.77	327	368	IPR001356	Homeobox domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 408 aa Download sequence Send to blast
MQRDAATGPY YPVADAGSLH SALISLGCSD LSHVMAGFPL PPAFGEETVA SSRVGDEFWS 60 TPSAPYTFEP SKIGVDSMFE APVEALPFDP TAGWVVPCPE LQESSITTRG AAPEPELSSS 120 GVSSHTSGSS LSLNFASCGA AFPAATPPFF EAMQEILAEF ASYALVNCDH TSPGSSDRSF 180 VFHNNNNNNN SNDSFSYGKE MEIESKKRHL MSLLQVVDDQ YNQCLDEIHT VVSAFHSVTE 240 VDPALHARFA LPTVSVMYRD LRERISRHIL AAGVGQAREE ERERSFETSL VHKQWALEQL 300 KKKDHHLWRP QRGLPERSVS VLRAWMFHNF LHPYPKDAEK HLLALKSGLT RSQVSNWFIN 360 ARVRLWKPMI EEMYAEMNRR KAPRNQEEAI NGSHRNLLRF ESRRFTVD

Sequence ? help Back to Top

Protein Sequence Length: 408 aa Download sequence Send to blast

MQRDAATGPY YPVADAGSLH SALISLGCSD LSHVMAGFPL PPAFGEETVA SSRVGDEFWS  60
TPSAPYTFEP SKIGVDSMFE APVEALPFDP TAGWVVPCPE LQESSITTRG AAPEPELSSS  120
GVSSHTSGSS LSLNFASCGA AFPAATPPFF EAMQEILAEF ASYALVNCDH TSPGSSDRSF  180
VFHNNNNNNN SNDSFSYGKE MEIESKKRHL MSLLQVVDDQ YNQCLDEIHT VVSAFHSVTE  240
VDPALHARFA LPTVSVMYRD LRERISRHIL AAGVGQAREE ERERSFETSL VHKQWALEQL  300
KKKDHHLWRP QRGLPERSVS VLRAWMFHNF LHPYPKDAEK HLLALKSGLT RSQVSNWFIN  360
ARVRLWKPMI EEMYAEMNRR KAPRNQEEAI NGSHRNLLRF ESRRFTVD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4xrm_A	4e-14	314	372	5	63	Homeobox protein Meis2
4xrm_B	4e-14	314	372	5	63	Homeobox protein Meis2
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor which may be involved in the signal transduction pathway downstream of the COP1 gene. Controls floral competency as a specific activator of FLC expression. Is responsive of the nuclear import of SHOOT MERISTEMLESS (STM). {ECO:0000269\|PubMed:17908157}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By light. In etiolated seedlings, maximally expressed after 3 days of illumination.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011096864.1	1e-117	homeobox protein ATH1 isoform X1
Refseq	XP_020550152.1	1e-116	homeobox protein ATH1-like
Swissprot	P48731	2e-93	ATH1_ARATH; Homeobox protein ATH1
TrEMBL	A0A4D8ZAN0	1e-149	A0A4D8ZAN0_SALSN; Uncharacterized protein
STRING	Migut.A00142.1.p	1e-111	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA8261	23	27

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G32980.1	2e-89	homeobox gene 1

Publications ? help Back to Top
Khan M, et al. Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis. Plant Physiol., 2015. 169(3): p. 2166-86 [PMID:26417006]