PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00004865-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

bHLH

Protein Properties

Length: 291aa MW: 33129.6 Da PI: 6.1621

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00004865-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	36.3	1e-11	151	194	6	54
HHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS HLH 6 nerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 ++ErrRR+r+N++++ Lr+++Pk + K++ +iL +++Y+++L SMil_00004865-RA_Salv 151 LMAERRRRKRLNDRLSMLRSIVPKiS------KMDRTSILGDTIDYMREL 194 589*******************66......*************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	4.84E-15	144	204	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.402	145	194	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.2E-12	151	200	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.9E-9	151	194	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.8E-15	152	204	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.90E-5	152	199	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 291 aa Download sequence Send to blast
MEQLTQHSSL LEELIMPPKI ESSFSTEFFQ NTWNFTPFDQ TPDFNLPFTN PSLLDLISPP 60 EFATPCPLGE FQPFLDALAS PDFGSLYDRD DLPPMSIPFL DGCIADFDGT FKLENSQISD 120 AINIDVYNNV DLYGERKSKS KKPDGQPSKN LMAERRRRKR LNDRLSMLRS IVPKISKMDR 180 TSILGDTIDY MRELLDKIQK LREEGVDEST AIRNYFKEQQ MQLRNPPKEK VGYPNRSVLH 240 GEAGAIAVYA RHARRHRPRL TTLCGGTTID VSSEDVKQAL FRNAGYGGRC L

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	153	160	ERRRRKRL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. May be involved in the differentiation of stomatal guard cells. {ECO:0000269\|PubMed:17088607}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KP257477	0.0	KP257477.1 Salvia miltiorrhiza clone 44 basic helix-loop-helix transcription factor mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011099455.1	4e-97	transcription factor bHLH93
Swissprot	Q9LSL1	5e-32	BH093_ARATH; Transcription factor bHLH93
TrEMBL	A0A0H3YB32	1e-170	A0A0H3YB32_SALMI; Basic helix-loop-helix transcription factor
STRING	Migut.H00297.1.p	3e-57	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA789	24	97

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G65640.1	4e-34	beta HLH protein 93

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Sharma N, et al. NO FLOWERING IN SHORT DAY (NFL) is a bHLH transcription factor that promotes flowering specifically under short-day conditions in Arabidopsis. Development, 2016. 143(4): p. 682-90 [PMID:26758694] Chen YS, et al. Two MYB-related transcription factors play opposite roles in sugar signaling in Arabidopsis. Plant Mol. Biol., 2017. 93(3): p. 299-311 [PMID:27866313] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]