PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00003117-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family HSF
Protein Properties Length: 542aa    MW: 59589.7 Da    PI: 4.5824
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00003117-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind105.15.9e-33331602102
                            HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTT............... CS
           HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekksks............... 74 
                            Fl k+y++++d+++++++sws ++nsf+v+d+ efa+++LpkyFkh+nf+SFvRQLn+Yg  + +   + + +               
  SMil_00003117-RA_Salv  33 FLVKTYDMVDDPSTDKIVSWSPTNNSFIVWDSAEFARDLLPKYFKHNNFSSFVRQLNTYGHVSFEFWFGADYElclfqfylcvlqkkg 120
                            9********************999**************************************9999998877799*********9999 PP

                            ............XTTSEEEEESXXXXXXXXXXXXXXXXXX CS
           HSF_DNA-bind  75 ............kekiweFkhksFkkgkkellekikrkks 102
                                        +++ weF+++ F +g+k+ll++i r+k 
  SMil_00003117-RA_Salv 121 spavafkgfrkvDPDRWEFANEGFLRGQKHLLKSITRRKP 160
                            99888877765449***********************986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF467853.4E-312899IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004151.7E-5129158IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene3DG3DSA:1.10.10.102.1E-3630158IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF004478.7E-2933158IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000566.2E-173356IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000566.2E-177183IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000566.2E-178496IPR000232Heat shock factor (HSF)-type, DNA-binding
SuperFamilySSF467853.4E-31126158IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.601.108.0E-4194315No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 542 aa     Download sequence    Send to blast
MEAAATPSSA TGGGGEAAPP PAPMPAANAP PPFLVKTYDM VDDPSTDKIV SWSPTNNSFI  60
VWDSAEFARD LLPKYFKHNN FSSFVRQLNT YGHVSFEFWF GADYELCLFQ FYLCVLQKKG  120
SPAVAFKGFR KVDPDRWEFA NEGFLRGQKH LLKSITRRKP AHGHPQHQQQ PNGQTPTVGA  180
CVEVGKFGLE EEVERLKRDK NVLMQELVRL RQQQQTTDGQ LQTMVQRLQG MEQRQQQMMS  240
FLAKAMNSPG FLAQFMQQPT DSNRRISEGN KKRRLKQDGM TDDSVSPSDG QIIKYQPLMN  300
EAAKAMLRQI MKLDSSARLE NFGNAPDSFL IRDGSSSSNA LECGSSSNHV SGVTLQEVPP  360
TSGPGFAPSG SSSAATSEVQ TPLVGACTEV SNIQFPCQSP VIGAEEVPLP PADGIISDLS  420
QMVPDSNVDI IGSEAGNEIF IDPTSLSGSS KLPFEIDGFS PDSPIEWENM DEIPELPSVS  480
DPFWEKFLQS PPPVDTEMDS TLTEDLPDGN EAKPPENGWD KSQHMAQLTE QMEHLTPDAK  540
KA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B4e-242515818129Heat shock factor protein 1
5d5v_B4e-242515818129Heat shock factor protein 1
5d5v_D4e-242515818129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1269276NKKRRLKQ
2270275KKRRLK
Functional Description ? help Back to Top
Source Description
UniProtDNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011070307.20.0LOW QUALITY PROTEIN: heat shock factor protein HSF8
SwissprotQ401520.0HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBLA0A4D9A9N50.0A0A4D9A9N5_SALSN; Heat shock transcription factor, other eukaryote
STRINGXP_009781208.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA64131931
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32330.11e-118heat shock transcription factor A1D
Publications ? help Back to Top
  1. Zhu B, et al.
    Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max).
    J. Plant Res., 2006. 119(3): p. 247-56
    [PMID:16570125]
  2. Cai SY, et al.
    HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants.
    J. Pineal Res., 2017.
    [PMID:28095626]
  3. Zhou J, et al.
    Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1.
    Plant Physiol., 2018. 176(3): p. 2456-2471
    [PMID:29339397]