PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | SMil_00002239-RA_Salv | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
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Family | E2F/DP | ||||||||
Protein Properties | Length: 537aa MW: 58400.8 Da PI: 4.6111 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 84.7 | 7e-27 | 191 | 256 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liek+ kn+i+wkg SMil_00002239-RA_Salv 191 RYDSSLGLLTKKFINLIKHAEDGVLDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKNLKNRIQWKG 256 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.0E-28 | 189 | 258 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 2.4E-34 | 191 | 256 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 8.84E-17 | 191 | 254 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 2.7E-24 | 193 | 256 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF144074 | 1.02E-31 | 269 | 373 | No hit | No description |
Pfam | PF16421 | 2.4E-31 | 272 | 371 | IPR032198 | E2F transcription factor, CC-MB domain |
CDD | cd14660 | 1.72E-40 | 285 | 373 | No hit | No description |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0010090 | Biological Process | trichome morphogenesis | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051302 | Biological Process | regulation of cell division | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005737 | Cellular Component | cytoplasm | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 537 aa Download sequence Send to blast |
MQRQTPPPPS SRKQLPFTSM RPPFGGGGGG GGGDYHHFAS GEAQRPDHEF VESVAVKKRP 60 VSCQALRSFL LNFELGLASI TGPLFIWSEM NGCWVLLSIC CSLCSFSGVV QVGLEPLKRK 120 SGVAEPEVEP ADHNAGPGNV TVPKGPFQTP PSAKSGKQKV SRSKANKAGS QIPIPNVGSP 180 SGNHTPVGPC RYDSSLGLLT KKFINLIKHA EDGVLDLNKA ADTLEVQKRR IYDITNVLEG 240 IGLIEKNLKN RIQWKGLDVA RPGEADESVP ALQEELENLN IEECRLDDRI REMQEKLRGL 300 SEDEGNERWL FVTEEDIKCL PCFQNETLIA IKAPHGTTLE VPDPDEAVDY PQRRYRIVLR 360 STMGPIDVYL VSQFEEKFEE INAVEEQPSI PAMQGVEANV YASVPSPKLE IGGHETAAQE 420 VEPQRMCLDA STSQDFVSGI LKIVPEVDIG ADYWLSSDAD ISYTDMWSIE SVIDWDSLDV 480 PDYATAGITT PRAQTPARNT TAASPSQAAV PSALPPDQIS STTTTTTTAT IPPSTTI |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 1e-25 | 186 | 257 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_011090314.1 | 0.0 | transcription factor E2FB isoform X1 | ||||
Swissprot | Q9FV71 | 1e-138 | E2FB_ARATH; Transcription factor E2FB | ||||
TrEMBL | A0A4D9AN86 | 0.0 | A0A4D9AN86_SALSN; Uncharacterized protein | ||||
STRING | Migut.N02463.1.p | 0.0 | (Erythranthe guttata) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA1077 | 24 | 84 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G22220.2 | 1e-134 | E2F transcription factor 1 |
Publications ? help Back to Top | |||
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