PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00000869-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family ARR-B
Protein Properties Length: 677aa    MW: 73649.8 Da    PI: 6.5692
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00000869-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like69.45.9e-222162581255
                G2-like  12 erFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                            e+Fv av+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl
  SMil_00000869-RA_Salv 216 EQFVTAVNQL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 258
                            79********.********************************8 PP
2Response_reg81.42.9e-27471551109
                            EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHH CS
           Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeeda 86 
                            vl+vdD+p+ +++l+++l++ +y ev+ ++ +e al+ll++++  +D+++ D+ mp+mdG++ll++i  e  +lp+i+++a ++++ +
  SMil_00000869-RA_Salv  47 VLVVDDDPTCLRILEKMLRNCRY-EVTKCSRAEVALKLLRDNKdgFDVVISDVHMPDMDGFKLLEHIGLEM-DLPVIMMSADDSKSVV 132
                            89*********************.***************888889**********************6654.8*************** PP

                            HHHHHTTESEEEESS--HHHHHH CS
           Response_reg  87 lealkaGakdflsKpfdpeelvk 109
                             + +  Ga d+l Kp+ +e+l +
  SMil_00000869-RA_Salv 133 MKGVTHGACDYLIKPVRMEALKN 155
                            ******************99986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.40.50.23004.8E-4344178No hitNo description
SuperFamilySSF521723.7E-3644168IPR011006CheY-like superfamily
SMARTSM004481.3E-3045157IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011042.67346161IPR001789Signal transduction response regulator, receiver domain
PfamPF000724.3E-2447155IPR001789Signal transduction response regulator, receiver domain
CDDcd001561.18E-2748160No hitNo description
PROSITE profilePS512949.79205261IPR017930Myb domain
PfamPF002491.2E-6212257IPR001005SANT/Myb domain
SuperFamilySSF466895.73E-15212262IPR009057Homeodomain-like
TIGRFAMsTIGR015572.7E-20212258IPR006447Myb domain, plants
Gene3DG3DSA:1.10.10.606.1E-23213263IPR009057Homeodomain-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 677 aa     Download sequence    Send to blast
LELLSCFVEF GPKKMNLGVN SMSLTTSSAS WKSGDAVSDQ FPAGLRVLVV DDDPTCLRIL  60
EKMLRNCRYE VTKCSRAEVA LKLLRDNKDG FDVVISDVHM PDMDGFKLLE HIGLEMDLPV  120
IMMSADDSKS VVMKGVTHGA CDYLIKPVRM EALKNIWQHV VRKKKYEWKE KDMEQSGSVE  180
DGGERQQKPS DDADYSSSAN EGNWRSSRKR KEEEDEQFVT AVNQLGIDKA VPKKILELMN  240
VPGLTRENVA SHLQKYRLYL RRLSGQPQNG LGNSFLGPQD GGFGSMSSLN GLDLQALASS  300
GQIPAQSLAT IQAAALSRVT NKSGISVPLV DQRNNIFSFD NPNIRFLDGQ QHHNNGKQVN  360
LLHGIPTNMD SKQLAAMHQS AQPFGNMHMN VHSQSGQSNS LLTQLVQPQS RTQMLNEVGS  420
NQVLNLPSSV GQPGLSQAIP GSVFSRYGID NVRAPTYASL SQPSSVVEFS RSQGIELSGN  480
TIPLSSNSGI PSFTSKGMLQ EEVNSEMKGP RGFLPNFDVF NELNQNRTDD WGLQNVGSSF  540
ESPQHSNAQG RLDVAPSVLV QPGFASDHRS GHIRATSVNK AAFSAASSLS NSTSLGQQQQ  600
QLTSSHGDNS LRIKTERLPD MGFGNSLFPD QFGQEDLMSA LLKQNAGING LDESGGSSKI  660
GMVVCDVFVC VSGGKIG
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011071400.10.0two-component response regulator ARR2 isoform X2
SwissprotQ9ZWJ91e-164ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A4D9A7R60.0A0A4D9A7R6_SALSN; Two-component response regulator ARR-B family
STRINGEOY066390.0(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA31912450
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G16857.11e-156response regulator 1
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  3. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  4. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  5. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  6. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  7. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  8. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  9. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]