PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

ERF

Protein Properties

Length: 218aa MW: 24663.8 Da PI: 9.0531

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Rsa1.0_07943.1_g00002.1	genome	RGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	61.8	1.6e-19	66	114	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+G+r+++ +g+W+AeIrdp++ r++lg+f taeeAa+a++ a+ +++g Rsa1.0_07943.1_g00002.1 66 YRGIRQRP-WGKWAAEIRDPRK---GVRVWLGTFKTAEEAARAYDSAAIQIRG 114 9*****.******954...4*********************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51032	24.671	65	122	IPR001471	AP2/ERF domain
SMART	SM00380	8.5E-39	65	128	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.05E-22	65	123	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	3.4E-33	65	123	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.9E-12	66	77	IPR001471	AP2/ERF domain
CDD	cd00018	8.79E-35	66	124	No hit	No description
Pfam	PF00847	3.5E-13	66	114	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.9E-12	88	104	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0034059	Biological Process	response to anoxia
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 218 aa Download sequence Send to blast
MCGGAVISDF IWSLRRPSFA EPDPSQLGYE GSVSIEKRTV CSVGGEKRKD GIEKKKGKKR 60 ERKNMYRGIR QRPWGKWAAE IRDPRKGVRV WLGTFKTAEE AARAYDSAAI QIRGGKAKLN 120 FPNDDSTRRN CIIKNKEVGG GLINASDDQQ STPLLPPLLK EDKENQEVKQ LSEELMAYED 180 YMSFYQIPYL DGQSATEDVP QQISLIGNLW SFQDNNNN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	5e-23	66	122	3	60	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
5wx9_A	2e-22	66	124	15	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	54	62	KKGKKRERK

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Rsa1.0_07943.1_g00002.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC002535	2e-61	AC002535.3 Arabidopsis thaliana chromosome 2 clone T30B22 map CIC06C03, complete sequence.
GenBank	AY074645	2e-61	AY074645.1 Arabidopsis thaliana At2g47520/T30B22.18 mRNA, complete cds.
GenBank	CP002685	2e-61	CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018480277.1	1e-142	PREDICTED: ethylene-responsive transcription factor ERF071
Swissprot	O22259	9e-63	ERF71_ARATH; Ethylene-responsive transcription factor ERF071
TrEMBL	A0A0D3C6Q8	1e-121	A0A0D3C6Q8_BRAOL; Uncharacterized protein
STRING	Bo4g198690.1	1e-122	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G47520.1	2e-51	ERF family protein

Publications ? help Back to Top
Gasch P, et al. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Plant Cell, 2016. 28(1): p. 160-80 [PMID:26668304] Yao Y,Chen X,Wu AM ERF-VII members exhibit synergistic and separate roles in Arabidopsis. Plant Signal Behav, 2017. 12(6): p. e1329073 [PMID:28537474] Eysholdt-Derzsó E,Sauter M Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling. Plant Physiol., 2017. 175(1): p. 412-423 [PMID:28698356] Eysholdt-Derzsó E,Sauter M Hypoxia and the group VII ethylene response transcription factor HRE2 promote adventitious root elongation in Arabidopsis. Plant Biol (Stuttg), 2019. 21 Suppl 1: p. 103-108 [PMID:29996004]