PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

NAC

Protein Properties

Length: 280aa MW: 31540.6 Da PI: 5.4018

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Rsa1.0_04448.1_g00002.1	genome	RGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	130.2	1.5e-40	6	136	3	128
NAM 3 pGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvkaeekewyfFskrdkkyatgkrknratksgyWkat 86 +GfrF Ptdeel++++Lk+k++g +++++++i+ev+i+++eP +Lp+ ++k++++ wyf s+++ ++++++ ++r+t sg+Wk+t Rsa1.0_04448.1_g00002.1 6 VGFRFCPTDEELINYFLKNKIQGIPCSIDDTIREVNICSYEPASLPAlsTIKSKDHVWYFLSPKEYTSTKKNVTKRTTPSGFWKST 91 7*************************99************4458889999************************** PP NAM 87 gkdkevlsk...kgelvglkktLvfykgrapkgektdWvmheyrl 128 g+d++v ++ +g ++g+kktLv+++g+++++++t W+mhe+++ Rsa1.0_04448.1_g00002.1 92 GNDRNVRKEkrrNGVVIGTKKTLVYHEGKSSSAVRTPWTMHEFNI 136 **9986667777*************************86 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51005	37.907	4	171	IPR003441	NAC domain
Pfam	PF02365	4.2E-23	6	135	IPR003441	NAC domain
SuperFamily	SSF101941	4.71E-42	6	139	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 280 aa Download sequence Send to blast
METNIVGFRF CPTDEELINY FLKNKIQGIP CSIDDTIREV NICSYEPASL PALSTIKSKD 60 HVWYFLSPKE YTSTKKNVTK RTTPSGFWKS TGNDRNVRKE KRRNGVVIGT KKTLVYHEGK 120 SSSAVRTPWT MHEFNITCLP PVDQGNVGDI PCGSNSPEPS HSSLVTDVSN IVGAANTPPP 180 GDQAGKESLY GFSVKDVTMI MEKQDDLCPW DALCKVPDTL FIDNNDNTNV KLQAPCLAQN 240 DDEFLGGLTH VNRKHVEFLF IYDQELTTQE NCEEYMLKWF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	5e-21	7	136	18	140	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Involved in salt stress response during seed germination and seedling growth. Binds the auxin-responsive IAA30 gene promoter and may serve as a molecular link that interconnects a developmental feedback loop of auxin signaling with a salt signal transduction pathway during seed germination (PubMed:21450938). {ECO:0000269\|PubMed:21450938}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Rsa1.0_04448.1_g00002.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salt stress and abscisic acid (ABA) in roots. {ECO:0000269\|PubMed:21450938}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013722780.1	1e-124	NAC domain-containing protein 69-like
Swissprot	Q9M126	2e-84	NAC69_ARATH; NAC domain-containing protein 69
TrEMBL	M4F5H2	1e-137	M4F5H2_BRARP; Uncharacterized protein
STRING	Bra036328.1-P	1e-138	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1982	19	71

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G01550.1	7e-87	NAC domain containing protein 69

Publications ? help Back to Top
Liang M, et al. Subcellular Distribution of NTL Transcription Factors in Arabidopsis thaliana. Traffic, 2015. 16(10): p. 1062-74 [PMID:26201836] He L, et al. Arabidopsis ANAC069 binds to C[A/G]CG[T/G] sequences to negatively regulate salt and osmotic stress tolerance. Plant Mol. Biol., 2017. 93(4-5): p. 369-387 [PMID:27975189]