PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Rsa1.0_03723.1_g00003.1
Organism
Raphanus sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family E2F/DP
Protein Properties Length: 469aa    MW: 51646.6 Da    PI: 4.8555
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Rsa1.0_03723.1_g00003.1genomeRGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP82.63.3e-26153218171
                  E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                              r+++sL+llt+kf++l++++e+g+v+ln++a++L   +v  ++RRiYDi+NVLe+++liek  kn+i wkg
  Rsa1.0_03723.1_g00003.1 153 RYDSSLGLLTRKFVDLIKQAEDGMVDLNKAAETL---EV--QKRRIYDITNVLEGIDLIEKPFKNRILWKG 218
                              6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.3E-27149220IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.31E-16153216IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-32153218IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.6E-22155218IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146603.86E-48229335No hitNo description
SuperFamilySSF1440741.78E-32230335No hitNo description
PfamPF164211.7E-32234333IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 469 aa     Download sequence    Send to blast
MSSGVRSSPG HSQPPPPSSS SNPVVPPIRR HLAFASTKPP FHPSDYRRFA PSYLTNNGEE  60
DAVVLRSPRN KCVYKVQSRK RKSMMDVVTT TTSCNSNGFT SSGSTSIHNT PLSAKRGRVN  120
TTKSKTKETH SLPQTPISNS GSPATLTPSG SCRYDSSLGL LTRKFVDLIK QAEDGMVDLN  180
KAAETLEVQK RRIYDITNVL EGIDLIEKPF KNRILWKGVD ASRPGDVDAE VSVLQAEIGN  240
LNLEEQALDN QIRETEDRLR NLSENEKNQK WLFVTEEDIK SLPGFQNQTL IAVKAPHGTT  300
LEVPDPDEAG DLPQRRYRII LRSTMGPIDV YLVSEFEETN GNIEPPACLP IASCSGSTEN  360
HDIEALAIDN TETAIEHQMS QDHNAHAQPG DTSDLNFLQE QVGGMLKIAP SDIENDDTDY  420
WLLSNAEISM TDIWNTDSGI DWDYGIADVR TPPPVMGEIA PAAIDSKPR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-22148219274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
17782SRKRKS
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapRsa1.0_03723.1_g00003.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018475572.10.0PREDICTED: transcription factor E2FA-like isoform X1
SwissprotQ9FNY00.0E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A0D3B5630.0A0A0D3B563_BRAOL; Uncharacterized protein
STRINGBo3g029900.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.10.0E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]