PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

ERF

Protein Properties

Length: 290aa MW: 31711.2 Da PI: 4.5961

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Rsa1.0_01856.1_g00002.1	genome	RGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	63.9	3.4e-20	97	146	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+W+AeIrdps r r +lg+++taeeAa +++a+ +l+g Rsa1.0_01856.1_g00002.1 97 KYRGVRQRP-WGKWAAEIRDPS----RrVRLWLGTYDTAEEAAIVYDNAAIQLRG 146 8******.******84....34***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.730.10	1.3E-30	96	154	IPR001471	AP2/ERF domain
Pfam	PF00847	5.7E-13	97	146	IPR001471	AP2/ERF domain
SMART	SM00380	2.2E-38	97	160	IPR001471	AP2/ERF domain
CDD	cd00018	2.98E-33	97	153	No hit	No description
PROSITE profile	PS51032	23.868	97	154	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	6.34E-22	97	154	IPR016177	DNA-binding domain
PRINTS	PR00367	1.4E-10	98	109	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.4E-10	120	136	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0042991	Biological Process	transcription factor import into nucleus
GO:0048825	Biological Process	cotyledon development
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 290 aa Download sequence Send to blast
METDKKVLKS MSTTTITQPR ILRISVSDPY ATDSSSDEDE GFSEISGKRR RVKKFVNEVV 60 LESTVPDKDR PKKKKRPNMN TNAKTTAETA VTAPARKYRG VRQRPWGKWA AEIRDPSRRV 120 RLWLGTYDTA EEAAIVYDNA AIQLRGPNAL TNFSPPPPAT ENGEEASKVS DGECLGSPVS 180 VLQTPFSGES TAAITVKEEF YGVSTTTAAV EVKEEPSITV SDTFTDFSSP LFLDDDVFGF 240 STSMPDCFGD GVFADMSFGF GSGSGFSSWH VEDHFQDIGD LFGSDPLLTV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	5e-21	93	164	1	70	ATERF1
3gcc_A	5e-21	93	164	1	70	ATERF1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	47	51	KRRRV
2	68	74	DRPKKKK
3	70	76	PKKKKRP

Functional Description ? help Back to Top
Source	Description
UniProt	Component of the cytokinin signaling pathway involved in cotyledons, leaves, and embryos development. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:16832061}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Rsa1.0_01856.1_g00002.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018474731.1	0.0	PREDICTED: ethylene-responsive transcription factor CRF1
Swissprot	O82503	1e-107	CRF1_ARATH; Ethylene-responsive transcription factor CRF1
TrEMBL	A0A3P6AUH4	1e-154	A0A3P6AUH4_BRAOL; Uncharacterized protein
STRING	Bo3g045150.1	1e-150	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G11140.1	1e-101	cytokinin response factor 1

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Raines T, et al. The cytokinin response factors modulate root and shoot growth and promote leaf senescence in Arabidopsis. Plant J., 2016. 85(1): p. 134-47 [PMID:26662515]