PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

NAC

Protein Properties

Length: 280aa MW: 31773.7 Da PI: 6.5285

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Rsa1.0_00722.1_g00002.1	genome	RGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	164.4	4.1e-51	7	131	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkat 86 lp+GfrFhPtdeelv++yL++k++++++++ vi+e+d+yk++Pw+Lp++ +ekewyfFs+rd+ky++g+r+nra+ +gyWkat Rsa1.0_00722.1_g00002.1 7 LPAGFRFHPTDEELVKFYLCRKCASEQISA-PVIAEIDLYKFNPWELPEMSLYGEKEWYFFSPRDRKYPNGSRPNRAAGTGYWKAT 91 799***********************99.89***********66566899************************** PP NAM 87 gkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 g dk++ + ++ g+kk Lvfy g+apkg kt+W+mheyrl Rsa1.0_00722.1_g00002.1 92 GADKPIGK--PKTLGIKKALVFYAGKAPKGIKTNWIMHEYRL 131 **98..778*************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	2.22E-60	3	159	IPR003441	NAC domain
PROSITE profile	PS51005	59.009	7	159	IPR003441	NAC domain
Pfam	PF02365	7.0E-27	8	131	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0008361	Biological Process	regulation of cell size
GO:0009416	Biological Process	response to light stimulus
GO:0009611	Biological Process	response to wounding
GO:0009620	Biological Process	response to fungus
GO:0009744	Biological Process	response to sucrose
GO:0009751	Biological Process	response to salicylic acid
GO:0009753	Biological Process	response to jasmonic acid
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0043424	Molecular Function	protein histidine kinase binding

Sequence ? help Back to Top
Protein Sequence Length: 280 aa Download sequence Send to blast
MKAELNLPAG FRFHPTDEEL VKFYLCRKCA SEQISAPVIA EIDLYKFNPW ELPEMSLYGE 60 KEWYFFSPRD RKYPNGSRPN RAAGTGYWKA TGADKPIGKP KTLGIKKALV FYAGKAPKGI 120 KTNWIMHEYR LANVDRSASV SKKNNLRLDD WVLCRIYNKK GTMEKYYPAD EKPRTTTTSM 180 ADQSSSPFDT SDSTYPNDSS SSGGGHVVSP DAKEVQSEPK WGDLEDALEA FDTSMFGSSM 240 DLLQSDGFVP QYLYQPDYFT PFQDPHEQKP FLNWSFAPQG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	4e-84	2	165	10	174	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Involved in disease resistance response (PubMed:16115070, PubMed:19625399). May function as repressor of pathogenesis-related proteins (PubMed:16115070). May function in the regulation of host basal defense responses against viral infection (PubMed:19625399). Transcriptional activator involved in responses to wounding and infection with tobamovirus (TMV) (PubMed:22937923). Binds to the DNA sequences 5'-AAAATATCT-3' and 5'AGATTTTT-3' of CYP734A1/BAS1 and CYP72C1/SOB7 promoters, respectively. Acts as suppressor of the brassinosteroid (BR)-inactivating enzymes CYP734A1/BAS1 and CYP72C1/SOB7, and prevents their expression in almost all tissues. Plays a central role in integrating BR homeostasis and seedling development. Regulates the spatial regulation of BR homeostasis and participates in the regulation of hypocotyl elongation and root growth by suppressing BR catabolism. Mediates connection between BR catabolism and photomorphogenesis (PubMed:26493403). Binds to, and transactivates the promoter of the auxin biosynthetic gene NIT2 (PubMed:22965747). Stress-responsive NAC transcription factor involved in ABA-inducible leaf senescence signaling (PubMed:26518251). Required for normal seed development and morphology (PubMed:18849494). {ECO:0000269\|PubMed:16115070, ECO:0000269\|PubMed:18849494, ECO:0000269\|PubMed:19625399, ECO:0000269\|PubMed:22937923, ECO:0000269\|PubMed:22965747, ECO:0000269\|PubMed:26493403, ECO:0000269\|PubMed:26518251}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Rsa1.0_00722.1_g00002.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding, salicylic acid (SA), methyl jasmonate, drought stress, dark and sucrose starvation (PubMed:16115070). Induced by chitin elicitor (chitooctaose) (PubMed:17722694). Induced by salicylic acid and infection with tobamovirus (TMV) (PubMed:19625399). By indole-3-acetonitrile, salicylic acid (SA), sodium nitroprusside (SNP), salt stress and drought stress (PubMed:22965747). Down-regulated by brassinosteroid (BR) and transition from dark to white light (PubMed:26493403). {ECO:0000269\|PubMed:16115070, ECO:0000269\|PubMed:17722694, ECO:0000269\|PubMed:19625399, ECO:0000269\|PubMed:22965747, ECO:0000269\|PubMed:26493403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY245880	0.0	AY245880.1 Brassica napus NAC-domain protein 3 (NAC3) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018445867.1	0.0	PREDICTED: protein ATAF2
Swissprot	Q9C598	0.0	NAC81_ARATH; Protein ATAF2
TrEMBL	A0A178URJ7	0.0	A0A178URJ7_ARATH; ATAF2
STRING	AT5G08790.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM190	28	276

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G08790.1	0.0	NAC family protein

Publications ? help Back to Top
Takasaki H, et al. SNAC-As, stress-responsive NAC transcription factors, mediate ABA-inducible leaf senescence. Plant J., 2015. 84(6): p. 1114-23 [PMID:26518251]