PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

bHLH

Protein Properties

Length: 230aa MW: 25568.2 Da PI: 10.215

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Rsa1.0_00517.1_g00003.1	genome	RGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.4	1.3e-08	137	177	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L Rsa1.0_00517.1_g00003.1 137 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 177 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.434	128	177	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	3.9E-14	129	187	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.44E-14	132	187	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.3E-14	134	183	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	6.3E-6	138	177	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.32E-6	151	182	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 230 aa Download sequence Send to blast
MDNSDMLMNM MMQQMEKLPD QFSNTNPNPN SHNIMMLSES STHPFFFNPN HTHLPLLDPN 60 LTHHHHQSGL SFRYAPSTSS SLPDKRGGGG DNANMAAMRE MIFRIAVMQP IHIDPESVKP 120 PKRKNVRISK DPQSVAARHR RERISERIRI LQRLVPGGTK MDTASMLDEA IHYVKFLKKQ 180 VQSLEEHAVV NGGGMASAQP GVGGGYGGKG GCGTMRSDHH QMLGNAQILR

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Rsa1.0_00517.1_g00003.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK175679	0.0	AK175679.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor (bHLH037), complete cds, clone: RAFL22-18-N14.
GenBank	AK175912	0.0	AK175912.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor (bHLH037), complete cds, clone: RAFL22-57-C09.
GenBank	AL132976	0.0	AL132976.2 Arabidopsis thaliana DNA chromosome 3, BAC clone F11C1.
GenBank	BT010607	0.0	BT010607.1 Arabidopsis thaliana At3g50330 gene, complete cds.
GenBank	CP002686	0.0	CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018469336.1	1e-171	PREDICTED: transcription factor HEC2
Swissprot	Q9SND4	1e-112	HEC2_ARATH; Transcription factor HEC2
TrEMBL	V4M015	1e-126	V4M015_EUTSA; Uncharacterized protein
STRING	XP_006404040.1	1e-127	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1559	27	91

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	3e-95	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]