PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID RrC9694_p3
Organism
Raphanus raphanistrum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family E2F/DP
Protein Properties Length: 489aa    MW: 53456.4 Da    PI: 4.7238
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
RrC9694_p3genomeMSUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP82.24.5e-26159224171
     E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                 r+++sL+llt+kf++l++++++g+++ln++a++L   +v  ++RRiYDi+NVLe+++liek  kn+i wkg
  RrC9694_p3 159 RYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETL---EV--QKRRIYDITNVLEGIDLIEKPFKNRILWKG 224
                 6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.107.5E-28155226IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.2E-32159224IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.63E-16159222IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023199.3E-23161224IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146604.18E-44237351No hitNo description
SuperFamilySSF1440742.62E-28238351No hitNo description
PfamPF164212.8E-31241349IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 489 aa     Download sequence    Send to blast
PPQHSPSSSS VPVVPPIRRH LAFASTKPPF NPSDYHRFAP PHLTNNDRSL VNLCGAVDRE  60
DDVVVHRSPS RKRKSSVDVV AASSNSNGFT SSGFSTISSS PCKTPVSAKG GRVNTKSKAK  120
GNQSVPQTPI SNASQRADCF FNDEVVGSPP TLTPSGSCRY DSSLGLLTKK FVNLIKQAKD  180
GMLDLNKAAE TLEVQKRRIY DITNVLEGID LIEKPFKNRI LWKGVDTSGA GDVDADVSVV  240
QAEIENLSLE EQALDNQIRE TEERLRDLSE NEKNQKHLTN LLPMSRWLFV TEEDIKTLPG  300
FQNQTLIAVK APHGTTLEVP DPDEAVDSPQ RRYRIILRST MGPIDVYLVS EFEKKFEETN  360
GAAAPAACLP IASCSGSSEN HDIEALTVDN KGTDNEHHQV SQDHAQAQPG DASDLNYLQE  420
QVGGMLKITP SDVENDDADY WLLSNADISM TDIWKTDSGI DWDYEIADVS TPPPVMGEIA  480
PTGIDSTPR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-23154225274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
16974SRKRKS
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00293DAPTransfer from AT2G36010Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankJN9429840.0JN942984.1 Brassica juncea E2F transcription factor (E2Fa) mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018477559.10.0PREDICTED: transcription factor E2FA-like
RefseqXP_018477589.10.0PREDICTED: transcription factor E2FA-like
SwissprotQ9FNY00.0E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A078HYU50.0A0A078HYU5_BRANA; BnaAnng07700D protein
TrEMBLA0A397ZRS80.0A0A397ZRS8_BRACM; Uncharacterized protein
TrEMBLA0A3P6CQQ40.0A0A3P6CQQ4_BRACM; Uncharacterized protein
STRINGBra017268.1-P0.0(Brassica rapa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.10.0E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]