PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

HD-ZIP

Protein Properties

Length: 272aa MW: 30440.3 Da PI: 8.7364

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
RrC5602_p1	genome	MSU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	60.1	3.5e-19	127	181	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ +++k+q +Le+ F+++++++ +++ LAkklgLt rqV vWFqNrRa+ k RrC5602_p1 127 RKKLRLSKDQSAVLEDTFKEHNTLNPKQKLALAKKLGLTARQVEVWFQNRRARTK 181 677889***********************************************98 PP
2	HD-ZIP_I/II	122.9	1.5e-39	127	216	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreel 91 +kk+rlsk+q+++LE++F+e+++L+p++K +la++Lgl++rqv+vWFqnrRARtk+kq+E+d+e+Lkr++++l+een+rLeke +eLr +l RrC5602_p1 127 RKKLRLSKDQSAVLEDTFKEHNTLNPKQKLALAKKLGLTARQVEVWFQNRRARTKLKQTEVDCEYLKRCVEKLTEENRRLEKEAAELR-AL 216 69*************************************************************************************9.54 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04618	9.1E-27	2	95	IPR006712	HD-ZIP protein, N-terminal
Gene3D	G3DSA:1.10.10.60	3.7E-18	108	181	IPR009057	Homeodomain-like
SuperFamily	SSF46689	7.94E-19	113	184	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.054	123	183	IPR001356	Homeobox domain
SMART	SM00389	6.7E-18	125	187	IPR001356	Homeobox domain
Pfam	PF00046	1.4E-16	127	181	IPR001356	Homeobox domain
CDD	cd00086	2.09E-16	127	184	No hit	No description
PRINTS	PR00031	7.0E-6	154	163	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	158	181	IPR017970	Homeobox, conserved site
PRINTS	PR00031	7.0E-6	163	179	IPR000047	Helix-turn-helix motif
Pfam	PF02183	7.6E-8	183	217	IPR003106	Leucine zipper, homeobox-associated
SMART	SM00340	3.5E-23	183	226	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010582	Biological Process	floral meristem determinacy
GO:0048467	Biological Process	gynoecium development
GO:0080127	Biological Process	fruit septum development
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0043621	Molecular Function	protein self-association

Sequence ? help Back to Top
Protein Sequence Length: 272 aa Download sequence Send to blast
MMMGKEDLGL SLSLGFAQNH HPLQLNLKPT SPPMSNHQMF PWNQTFVSST SDQQSLRKID 60 VNSLPSTVDL EEETGVSSPN STISSTVSGK RRSERQGSGD DLDIALDRSS SRGTSDEEEE 120 YGGDGCRKKL RLSKDQSAVL EDTFKEHNTL NPKQKLALAK KLGLTARQVE VWFQNRRART 180 KLKQTEVDCE YLKRCVEKLT EENRRLEKEA AELRALKLSP GLYGKMSPPT TLLMCPSCER 240 VGGPSNHSQR SVSLNPWLQM AHGSSFDVKH PR

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	175	183	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00050	PBM	Transfer from AT4G17460	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ441252	1e-144	AJ441252.1 Arabidopsis thaliana mRNA for homeodomain-leucine zipper protein HAT1.
GenBank	AK228587	1e-144	AK228587.1 Arabidopsis thaliana mRNA for homeobox-leucine zipper protein HAT1, complete cds, clone: RAFL15-36-J21.
GenBank	ATU09332	1e-144	U09332.1 Arabidopsis thaliana clone HAT1 homeobox protein mRNA, complete cds.
GenBank	BT005756	1e-144	BT005756.1 Arabidopsis thaliana clone RAFL15-36-J21 (R50164) putative homeobox-leucine zipper protein HAT1 (HD-Zip protein 1) (At4g17460) mRNA, complete cds.
GenBank	BT006112	1e-144	BT006112.1 Arabidopsis thaliana clone U50164 putative homeobox-leucine zipper protein HAT1 (HD-Zip protein 1) (At4g17460) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018455167.1	0.0	PREDICTED: homeobox-leucine zipper protein HAT1
Swissprot	P46600	1e-176	HAT1_ARATH; Homeobox-leucine zipper protein HAT1
TrEMBL	A0A078JMR3	0.0	A0A078JMR3_BRANA; BnaAnng23540D protein
TrEMBL	A0A398AQ90	0.0	A0A398AQ90_BRACM; Uncharacterized protein
STRING	Bo1g051520.1	0.0	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1563	26	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G17460.1	1e-152	Homeobox-leucine zipper protein 4 (HB-4) / HD-ZIP protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zou LJ, et al. Role of Transcription Factor HAT1 in Modulating Arabidopsis thaliana Response to Cucumber mosaic virus. Plant Cell Physiol., 2016. 57(9): p. 1879-89 [PMID:27328697] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171] Tan W, et al. Transcription factor HAT1 is a substrate of SnRK2.3 kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought. PLoS Genet., 2018. 14(4): p. e1007336 [PMID:29659577]