PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

HSF

Protein Properties

Length: 492aa MW: 55143.1 Da PI: 4.427

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
RrC3959_p4	genome	MSU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	114.1	9.2e-36	42	133	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 Fl+k+y++++d+++++++sws n+nsf+v+d+ +fak++Lpk Fkh+nf+SFvRQLn+YgF+kv+ ++ weF+++ F +g+k+ll++i RrC3959_p4 42 FLSKTYDMVDDPATDSIVSWSGNNNSFIVWDPPQFAKDLLPKNFKHNNFSSFVRQLNTYGFRKVDPDK---------WEFANEGFLRGQKHLLKTIT 129 9******************999*************************************999.........****************** PP XXXX CS HSF_DNA-bind 99 rkks 102 r+k RrC3959_p4 130 RRKP 133 *986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	5.7E-39	36	126	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	4.42E-36	37	131	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	2.7E-62	38	131	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	5.1E-19	42	65	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	3.5E-31	42	131	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	5.1E-19	80	92	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	81	105	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	5.1E-19	93	105	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009408	Biological Process	response to heat
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 492 aa Download sequence Send to blast
MDPDNRTSTD GGGSVTMEST EIQPTPQPQP VAVLSGNAPP PFLSKTYDMV DDPATDSIVS 60 WSGNNNSFIV WDPPQFAKDL LPKNFKHNNF SSFVRQLNTY GFRKVDPDKW EFANEGFLRG 120 QKHLLKTITR RKPAHGHGHG HQQSQHSIGQ NSSVSSCVEV GKFGLKEEVE RLKRDKNVLM 180 QELVRLRQQQ QSTDNQLQTM VQRLQGMENR QQQLMSFLAK AVQSPHFLSQ FLQQQNQQNE 240 SSRRISDTSK KRRFRRDGIV SNNKESASPD GQIVKYQPPM HEQAKAMFSQ LMNMEPYKTG 300 DDGFLLGNGT STTEGTEMEI SSNNVAGITL QEMPTASEIQ SSSSPSGATP ENVTVAEFPT 360 PDEAIPSPDD PSLPEFADIL PENMAEVPPE NFLETNMEDM STILDSDLFN SDDLPFDFDD 420 ILRDPDLEPS VDDYASLFQD ILMSSPVPED MDVTPVDVRT KDSETEKKQM DNLTQQMGLL 480 SPETIDHSRQ NP

Sequence ? help Back to Top

Protein Sequence Length: 492 aa Download sequence Send to blast

MDPDNRTSTD GGGSVTMEST EIQPTPQPQP VAVLSGNAPP PFLSKTYDMV DDPATDSIVS  60
WSGNNNSFIV WDPPQFAKDL LPKNFKHNNF SSFVRQLNTY GFRKVDPDKW EFANEGFLRG  120
QKHLLKTITR RKPAHGHGHG HQQSQHSIGQ NSSVSSCVEV GKFGLKEEVE RLKRDKNVLM  180
QELVRLRQQQ QSTDNQLQTM VQRLQGMENR QQQLMSFLAK AVQSPHFLSQ FLQQQNQQNE  240
SSRRISDTSK KRRFRRDGIV SNNKESASPD GQIVKYQPPM HEQAKAMFSQ LMNMEPYKTG  300
DDGFLLGNGT STTEGTEMEI SSNNVAGITL QEMPTASEIQ SSSSPSGATP ENVTVAEFPT  360
PDEAIPSPDD PSLPEFADIL PENMAEVPPE NFLETNMEDM STILDSDLFN SDDLPFDFDD  420
ILRDPDLEPS VDDYASLFQD ILMSSPVPED MDVTPVDVRT KDSETEKKQM DNLTQQMGLL  480
SPETIDHSRQ NP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ldu_A	2e-26	40	131	18	120	Heat shock factor protein 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC189255	0.0	AC189255.2 Brassica rapa subsp. pekinensis cultivar Inbred line 'Chiifu' clone KBrB019O20, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018440991.1	0.0	PREDICTED: heat stress transcription factor A-1d
Swissprot	Q9LQM7	0.0	HFA1D_ARATH; Heat stress transcription factor A-1d
TrEMBL	A0A0D3CDP8	0.0	A0A0D3CDP8_BRAOL; Uncharacterized protein
STRING	Bo5g048950.1	0.0	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6470	24	40

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G32330.1	0.0	heat shock transcription factor A1D

Publications ? help Back to Top
Higashi Y, et al. HsfA1d, a protein identified via FOX hunting using Thellungiella salsuginea cDNAs improves heat tolerance by regulating heat-stress-responsive gene expression. Mol Plant, 2013. 6(2): p. 411-22 [PMID:23393165] Jung HS, et al. Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9 [PMID:23918368] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Ohama N, et al. The Transcriptional Cascade in the Heat Stress Response of Arabidopsis Is Strictly Regulated at the Level of Transcription Factor Expression. Plant Cell, 2016. 28(1): p. 181-201 [PMID:26715648]