PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

ERF

Protein Properties

Length: 301aa MW: 33775.8 Da PI: 5.0198

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
RrC3527_p2	genome	MSU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	67.6	2.4e-21	154	204	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+++AeIrdp+++g r++lg+f+ta eAa+a+++a+ +l+g RrC3527_p2 154 HYRGVRQRP-WGKYAAEIRDPNKRG--SRIWLGTFDTAIEAARAYDEAAFRLRG 204 7******.******96655..***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	4.45E-23	154	214	IPR016177	DNA-binding domain
SMART	SM00380	1.6E-37	154	218	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	24.329	154	212	IPR001471	AP2/ERF domain
CDD	cd00018	1.18E-32	154	212	No hit	No description
Pfam	PF00847	6.2E-15	154	204	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	3.5E-33	154	213	IPR001471	AP2/ERF domain
PRINTS	PR00367	9.9E-11	155	166	IPR001471	AP2/ERF domain
PRINTS	PR00367	9.9E-11	178	194	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010200	Biological Process	response to chitin
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 301 aa Download sequence Send to blast
MASHSEVSAL WFIEKHLLDE LSPVATDRWM IQESASTESS SDSSPMIFGS SSSSLAPVDF 60 SESPFKPEII DLSTPRFMDL ISVSDFDFKP SYQTGNQFEP DLKTQIPSAS DDDSQSNRKP 120 PLKISVPTKT GWIKFNPQPE VAKPSQAIAE EREHYRGVRQ RPWGKYAAEI RDPNKRGSRI 180 WLGTFDTAIE AARAYDEAAF RLRGSKAILN FPLEVGKWKK PRSDADGEKK RKREDIDDED 240 VKVAEKVLKT EQNVNSGESV PFVTSNLTEL CDWDLTGFLN FPLLSPLSPH PSFGYSKLTV 300 V

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	2e-29	153	215	1	63	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A	2e-29	153	215	4	66	ATERF1
3gcc_A	2e-29	153	215	4	66	ATERF1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	218	231	KKPRSDADGEKKRK

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269\|PubMed:10715325, ECO:0000269\|PubMed:9756931}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00549	DAP	Transfer from AT5G47230	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Ethylene induction is completely dependent on a functional ETHYLENE-INSENSITIVE2 (EIN2). Wounding as well as cold stress induction does not require EIN2. Transcripts accumulate strongly in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by jasmonate, Alternaria brassicicola, exogenous abscisic acid (ABA), cold, heat, NaCl or drought stress. {ECO:0000269\|PubMed:10715325}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013609112.1	1e-164	PREDICTED: ethylene-responsive transcription factor 5-like
Refseq	XP_013712994.1	1e-164	ethylene-responsive transcription factor 5
Swissprot	O80341	1e-138	EF102_ARATH; Ethylene-responsive transcription factor 5
TrEMBL	A0A078GLD8	1e-162	A0A078GLD8_BRANA; BnaC09g20100D protein
TrEMBL	A0A0D3E774	1e-162	A0A0D3E774_BRAOL; Uncharacterized protein
STRING	Bo9g069410.1	1e-163	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G47230.1	1e-103	ethylene responsive element binding factor 5

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546]