PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

NAC

Protein Properties

Length: 309aa MW: 35261 Da PI: 9.0236

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
RrC344_p10	genome	MSU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	152.3	2.3e-47	7	160	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k............................kvkaeekewyfFskrdkkyat 70 lp+GfrFhPtdeelv++yL +k++++++++ vi+e+d+yk++Pw+Lp k v+ ++++wyfFs+rd+ky++ RrC344_p10 7 LPAGFRFHPTDEELVKFYLIRKCSSEQISA-PVIAEIDLYKFNPWELPgKsfngkdssfflfisrivvkfvlffslnrDVSVRRERWYFFSPRDRKYPN 104 799***********************99.89***********6489**********9999999988876666888********** PP NAM 71 gkrknratksgyWkatgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 g+r+nra+ sgyWkatg dk++ + ++ g+kk Lvfy g+apkg kt+W+mheyrl RrC344_p10 105 GSRPNRAAGSGYWKATGADKPIGK--PKTLGIKKALVFYAGKAPKGIKTNWIMHEYRL 160 ******************98..778*************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	6.15E-20	3	67	IPR003441	NAC domain
PROSITE profile	PS51005	55.012	7	188	IPR003441	NAC domain
Pfam	PF02365	2.7E-26	8	160	IPR003441	NAC domain
SuperFamily	SSF101941	4.45E-35	87	188	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 309 aa Download sequence Send to blast
MKAELNLPAG FRFHPTDEEL VKFYLIRKCS SEQISAPVIA EIDLYKFNPW ELPGKSFNGK 60 DSSFFLFISR IVVKFVLFFS LNRDVSVRRE RWYFFSPRDR KYPNGSRPNR AAGSGYWKAT 120 GADKPIGKPK TLGIKKALVF YAGKAPKGIK TNWIMHEYRL ANVDRSASVN KKNNLRLDDW 180 VLCRIYNKKG TMEKYHPADE KPRIITTTAS SPFDTSVSST LQEEDCSSSG GHVVSPDAKE 240 EVQSEPKWRE LEDALEAFDS SMFGGSMDSL QSDGFVPQFM YQPTDCFTSF FQDPLEQKPF 300 LNWSFAPQG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	3e-73	2	194	10	174	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Involved in disease resistance response (PubMed:16115070, PubMed:19625399). May function as repressor of pathogenesis-related proteins (PubMed:16115070). May function in the regulation of host basal defense responses against viral infection (PubMed:19625399). Transcriptional activator involved in responses to wounding and infection with tobamovirus (TMV) (PubMed:22937923). Binds to the DNA sequences 5'-AAAATATCT-3' and 5'AGATTTTT-3' of CYP734A1/BAS1 and CYP72C1/SOB7 promoters, respectively. Acts as suppressor of the brassinosteroid (BR)-inactivating enzymes CYP734A1/BAS1 and CYP72C1/SOB7, and prevents their expression in almost all tissues. Plays a central role in integrating BR homeostasis and seedling development. Regulates the spatial regulation of BR homeostasis and participates in the regulation of hypocotyl elongation and root growth by suppressing BR catabolism. Mediates connection between BR catabolism and photomorphogenesis (PubMed:26493403). Binds to, and transactivates the promoter of the auxin biosynthetic gene NIT2 (PubMed:22965747). Stress-responsive NAC transcription factor involved in ABA-inducible leaf senescence signaling (PubMed:26518251). Required for normal seed development and morphology (PubMed:18849494). {ECO:0000269\|PubMed:16115070, ECO:0000269\|PubMed:18849494, ECO:0000269\|PubMed:19625399, ECO:0000269\|PubMed:22937923, ECO:0000269\|PubMed:22965747, ECO:0000269\|PubMed:26493403, ECO:0000269\|PubMed:26518251}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding, salicylic acid (SA), methyl jasmonate, drought stress, dark and sucrose starvation (PubMed:16115070). Induced by chitin elicitor (chitooctaose) (PubMed:17722694). Induced by salicylic acid and infection with tobamovirus (TMV) (PubMed:19625399). By indole-3-acetonitrile, salicylic acid (SA), sodium nitroprusside (SNP), salt stress and drought stress (PubMed:22965747). Down-regulated by brassinosteroid (BR) and transition from dark to white light (PubMed:26493403). {ECO:0000269\|PubMed:16115070, ECO:0000269\|PubMed:17722694, ECO:0000269\|PubMed:19625399, ECO:0000269\|PubMed:22965747, ECO:0000269\|PubMed:26493403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY245882	0.0	AY245882.1 Brassica napus NAC-domain protein 5-7 (NAC5-7) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018472839.1	0.0	PREDICTED: protein ATAF2-like
Swissprot	Q9C598	1e-165	NAC81_ARATH; Protein ATAF2
TrEMBL	A0A3P5ZEU9	1e-175	A0A3P5ZEU9_BRACM; Uncharacterized protein (Fragment)
STRING	Bra006015.1-P	1e-176	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM190	28	276

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G08790.1	1e-167	NAC family protein

Publications ? help Back to Top
Takasaki H, et al. SNAC-As, stress-responsive NAC transcription factors, mediate ABA-inducible leaf senescence. Plant J., 2015. 84(6): p. 1114-23 [PMID:26518251]