PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

NAC

Protein Properties

Length: 326aa MW: 37103.2 Da PI: 7.6332

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
RrC3365_p1	genome	MSU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	179.2	1.1e-55	20	146	1	129
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgel 99 lppGfrFhP deel+++yLk+kv ++ +++ +i evd++kvePwdLp k+k +ekewyfF+ rd+ky+tg r+nratk+gyWkatgkdke+++ +++l RrC3365_p1 20 LPPGFRFHPADEELISYYLKPKVLNSLFSA-VAIGEVDLNKVEPWDLPWKAKIGEKEWYFFCVRDRKYPTGLRTNRATKAGYWKATGKDKEIFK-EKSL 116 79***********************999.67***********98999**************************************.999 PP NAM 100 vglkktLvfykgrapkgektdWvmheyrle 129 vg+kktLvfykgrapkg+kt+Wvmheyrle RrC3365_p1 117 VGMKKTLVFYKGRAPKGVKTNWVMHEYRLE 146 ****************************85 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	7.06E-61	17	170	IPR003441	NAC domain
PROSITE profile	PS51005	57.82	20	170	IPR003441	NAC domain
Pfam	PF02365	1.5E-29	21	145	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009611	Biological Process	response to wounding
GO:0042542	Biological Process	response to hydrogen peroxide
GO:0051091	Biological Process	positive regulation of sequence-specific DNA binding transcription factor activity
GO:1900057	Biological Process	positive regulation of leaf senescence
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 326 aa Download sequence Send to blast
MDREVSRTRE IVEDSELIDL PPGFRFHPAD EELISYYLKP KVLNSLFSAV AIGEVDLNKV 60 EPWDLPWKAK IGEKEWYFFC VRDRKYPTGL RTNRATKAGY WKATGKDKEI FKEKSLVGMK 120 KTLVFYKGRA PKGVKTNWVM HEYRLEGEYA IDNLPKTAKN EWVISRVFQK QGDGKKMHIS 180 SLRMLGSGIN QFKPVGLPPL MDSSTYLKSR GDTFAGSLSH VTCFSDQTTE DKSHFSESKD 240 ECNFTMIGSS STHLIPNIGS MFHHNPVFMQ DNSSILKMLL DSEETQFKKN LQDLGTSDNE 300 LIASSWNGHD ISGSTAPVEV ACFWNF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	9e-53	18	176	15	171	NO APICAL MERISTEM PROTEIN
1ut4_B	9e-53	18	176	15	171	NO APICAL MERISTEM PROTEIN
1ut7_A	9e-53	18	176	15	171	NO APICAL MERISTEM PROTEIN
1ut7_B	9e-53	18	176	15	171	NO APICAL MERISTEM PROTEIN
3swm_A	1e-52	18	176	18	174	NAC domain-containing protein 19
3swm_B	1e-52	18	176	18	174	NAC domain-containing protein 19
3swm_C	1e-52	18	176	18	174	NAC domain-containing protein 19
3swm_D	1e-52	18	176	18	174	NAC domain-containing protein 19
3swp_A	1e-52	18	176	18	174	NAC domain-containing protein 19
3swp_B	1e-52	18	176	18	174	NAC domain-containing protein 19
3swp_C	1e-52	18	176	18	174	NAC domain-containing protein 19
3swp_D	1e-52	18	176	18	174	NAC domain-containing protein 19
4dul_A	9e-53	18	176	15	171	NAC domain-containing protein 19
4dul_B	9e-53	18	176	15	171	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to DNA in promoters of target genes on a specific bipartite motif 5'-[AG]CGT[AG](4-5n)[AG][CT]ACGCAA-3' (PubMed:16359384, PubMed:21303842). Triggers the expression of senescence-associated genes during age-, salt- and dark-induced senescence through a regulatory network that may involve cross-talk with salt- and H(2)O(2)-dependent signaling pathways (PubMed:21303842). {ECO:0000269\|PubMed:16359384, ECO:0000269\|PubMed:21303842}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Rapidly and strongly induced by H(2)O(2) treatment in both leaves and roots. Accumulates during senescence and in response to wounding. {ECO:0000269\|PubMed:21303842}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KF738272	0.0	KF738272.1 Brassica napus NAC transcription factor 59 (NAC59.1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018454635.1	0.0	PREDICTED: NAC domain-containing protein 59-like
Swissprot	Q9LJW3	1e-168	NAC59_ARATH; NAC domain-containing protein 59
TrEMBL	A0A3P5XUK5	0.0	A0A3P5XUK5_BRACM; Uncharacterized protein
TrEMBL	M4F567	0.0	M4F567_BRARP; Uncharacterized protein
STRING	Bra036223.1-P	0.0	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM400	28	174

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G29035.1	1e-170	NAC domain containing protein 3

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Manacorda CA, et al. Salicylic acid determines differential senescence produced by two Turnip mosaic virus strains involving reactive oxygen species and early transcriptomic changes. Mol. Plant Microbe Interact., 2013. 26(12): p. 1486-98 [PMID:23945002] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]