PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

NAC

Protein Properties

Length: 312aa MW: 35161.3 Da PI: 7.8293

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
RrC2787_p1	genome	MSU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	171	3.7e-53	16	144	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk..kg 97 lppGfrFhPtdeelv +yLk+k+++++l++ +i++vd+yk++Pw+Lp+k+ +e+ewyfFs+rd+ky++g r+nra++sgyWkatg+dk+v+s+ ++ RrC2787_p1 16 LPPGFRFHPTDEELVIHYLKRKADSSPLPV-AIIADVDLYKHDPWELPEKALFGEQEWYFFSPRDRKYPNGARPNRAATSGYWKATGTDKPVISTgdGS 113 79**************************.88***********8888899***********************************98888 PP NAM 98 elvglkktLvfykgrapkgektdWvmheyrl 128 ++vg+kk Lvfy+g+ pkg+k+dW+mheyrl RrC2787_p1 114 KKVGVKKALVFYTGKPPKGVKSDWIMHEYRL 144 99*************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	3.14E-65	12	176	IPR003441	NAC domain
PROSITE profile	PS51005	61.925	16	175	IPR003441	NAC domain
Pfam	PF02365	5.2E-28	17	144	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0045995	Biological Process	regulation of embryonic development
GO:0048317	Biological Process	seed morphogenesis
GO:0080060	Biological Process	integument development
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 312 aa Download sequence Send to blast
MESTDSSGGP PPQPNLPPGF RFHPTDEELV IHYLKRKADS SPLPVAIIAD VDLYKHDPWE 60 LPEKALFGEQ EWYFFSPRDR KYPNGARPNR AATSGYWKAT GTDKPVISTG DGSKKVGVKK 120 ALVFYTGKPP KGVKSDWIMH EYRLTDNKPS LRCDFGHKKN SLRLDDWVLC RIYKKNNSTS 180 SRHHHRHLDI DKDHHHHHFH HDMTTDDDLY RLPLSIPGQN VSRMNIYPAA IYDGGGGYSM 240 NHDFATSSGL NQKPNIPMPF WDQDPAKRFN GGVGDCSDIV SSVAAAPLMQ QQGGGLEEGL 300 DRTSYQLTGL NW

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	7e-74	15	178	14	171	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	May encode a transcription factor involved in the elaboration of shoot apical meristems (SAM) (Probable). Together with NAC056/NARS1, regulates embryogenesis by regulating the development and degeneration of ovule integuments, a process required for intertissue communication between the embryo and the maternal integument (PubMed:18849494). {ECO:0000269\|PubMed:18849494, ECO:0000305}.
UniProt	Transcription factor of the NAC family (Probable). Together with NAC018/NARS2, regulates embryogenesis by regulating the development and degeneration of ovule integuments, a process required for intertissue communication between the embryo and the maternal integument (PubMed:18849494). {ECO:0000269\|PubMed:18849494, ECO:0000305}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00201	DAP	Transfer from AT1G52880	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By Jasmonic acid (JA). {ECO:0000269\|PubMed:16805732}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KF974757	0.0	KF974757.1 Brassica napus NAC transcription factor 18-1 (NAC18-1.1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018469627.1	0.0	PREDICTED: NAC domain-containing protein 18
Swissprot	Q9LD44	1e-119	NAC56_ARATH; NAC transcription factor 56
Swissprot	Q9ZNU2	1e-119	NAC18_ARATH; NAC domain-containing protein 18
TrEMBL	A0A397Z0S5	0.0	A0A397Z0S5_BRACM; Uncharacterized protein
STRING	Bra018997.1-P	0.0	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM190	28	276

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G15510.1	1e-108	NAC domain containing protein 2

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Wang YX Characterization of a novel Medicago sativa NAC transcription factor gene involved in response to drought stress. Mol. Biol. Rep., 2013. 40(11): p. 6451-8 [PMID:24057250] Raherison ES,Giguère I,Caron S,Lamara M,MacKay JJ Modular organization of the white spruce (Picea glauca) transcriptome reveals functional organization and evolutionary signatures. New Phytol., 2015. 207(1): p. 172-87 [PMID:25728802] Du Q,Wang H The role of HD-ZIP III transcription factors and miR165/166 in vascular development and secondary cell wall formation. Plant Signal Behav, 2015. 10(10): p. e1078955 [PMID:26340415] Vialette-Guiraud AC, et al. A Conserved Role for the NAM/miR164 Developmental Module Reveals a Common Mechanism Underlying Carpel Margin Fusion in Monocarpous and Syncarpous Eurosids. Front Plant Sci, 2015. 6: p. 1239 [PMID:26793217]