PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID RrC264_p4
Organism
Raphanus raphanistrum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family NF-YC
Protein Properties Length: 872aa    MW: 96146.1 Da    PI: 5.6178
Description NF-YC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
RrC264_p4genomeMSUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NF-YC175.64.9e-55581611101
      NF-YC   1 qlksfwekq...iekatdfknhelPlarikkilkadedvkmisaeaPvllskacelfileltlrswlhaeenkrrtlkksdiaaavtrtdifdflvdivp 97 
                ql++fwe+q   iek+tdfknh+lPlarikki+kadedv+misaeaPv++++ace+fileltlrsw+h+eenkrrtl+k+diaaavtrtdifdflvdivp
  RrC264_p4  58 QLQVFWENQfkeIEKTTDFKNHSLPLARIKKIMKADEDVRMISAEAPVVFARACEMFILELTLRSWNHTEENKRRTLQKNDIAAAVTRTDIFDFLVDIVP 157
                89******99999*************************************************************************************** PP

      NF-YC  98 rdel 101
                r++l
  RrC264_p4 158 REDL 161
                *986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF471134.19E-3152152IPR009072Histone-fold
Gene3DG3DSA:1.10.20.105.6E-3772144IPR009072Histone-fold
PfamPF008084.4E-2180143IPR003958Transcription factor CBF/NF-Y/archaeal histone domain
Gene3DG3DSA:3.30.200.205.9E-35269402No hitNo description
CDDcd066069.47E-165288551No hitNo description
SuperFamilySSF561121.35E-86289581IPR011009Protein kinase-like domain
SMARTSM002205.1E-98289551IPR000719Protein kinase domain
PROSITE profilePS5001152.47289551IPR000719Protein kinase domain
PfamPF000692.4E-73290551IPR000719Protein kinase domain
PROSITE patternPS001070295318IPR017441Protein kinase, ATP binding site
Gene3DG3DSA:1.10.510.103.6E-53403557No hitNo description
PROSITE patternPS001080413425IPR008271Serine/threonine-protein kinase, active site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006979Biological Processresponse to oxidative stress
GO:0009908Biological Processflower development
GO:0046777Biological Processprotein autophosphorylation
GO:0004674Molecular Functionprotein serine/threonine kinase activity
GO:0005524Molecular FunctionATP binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 872 aa     Download sequence    Send to blast
MDQQEHGQSG AMNYGANPYQ TNPMTTNVAG SAGPAAPQGQ LAFHQIHQKQ QQQQLTQQLQ  60
VFWENQFKEI EKTTDFKNHS LPLARIKKIM KADEDVRMIS AEAPVVFARA CEMFILELTL  120
RSWNHTEENK RRTLQKNDIA AAVTRTDIFD FLVDIVPRED LRDEVLGRGT VPEAAAAGYP  180
YGYLPPGTGP IGNPGMVMGN PGGAYPPNPV KTKPPKSIEM QDFFGSVRRS LVFRPPAGDE  240
DNNQENQPPF PGVLADKITS CIRKSRALIK PSSSPPPPTT VDTPPPISWR KGQLIGRGAF  300
GTVYMGMNLD SGELLAVKQV LIASNYASKE KTQAHIQELE EEVKLLKNLS HPNIVRYLGT  360
VREDDTLNIL LEFVPGGSIS SLLEKFGPFP ESVVRTYTKQ LLFGLEYLHN HAIMHRDIKG  420
ANILVDNKGC IKLADFGASK QVAELATISG AKSMKGTPYW MAPEVILQTG HSFSADIWSV  480
GCTVIEMVTG KAPWSQQYKE VAAIFFIGTT KSHPPIPDTL SSDAKDFLLK CLQEEPKMRP  540
TASELLKHPF VTGQHKESAS TDLVSIMNNG STPTLSELTN TKCSPHSTCN DVGDMCNLGS  600
LNYSLASPFK SIQNNNFRQQ NDNGGEEDDM CLIDDDNFLT FNGESGPILK NNSDLKKSCD  660
ATSDISNALN AKFDESPCNG EKETKMSMEV DQPSYSEDDE ELTETKIKSF LDEKAAELKK  720
LQTPLYEEYY NNLITCSPSG MESNLSSSKR EDTARGFLKL PPKSRSPSRG PLGGSPSRAT  780
DTVSCTKSPG SGSSREVNMN DGGDEASQDT EEESKNQSAA LSEIEKKWKE ELDQELERKR  840
QEIMRQAGMG SSPRDRSLSR HREKSRFASP GK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4bf2_A2e-6129457942323MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
4bf2_B2e-6129457942323MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
4bhn_A2e-6129457942323MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
4bhn_B2e-6129457942323MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
4bib_A1e-6129457926307MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
4bib_B1e-6129457926307MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
4bic_A1e-6129457926307MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
4bic_B1e-6129457926307MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
4bid_A1e-6129457926307MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
4bid_B1e-6129457926307MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
4bie_A1e-6129457926307MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
4bie_B1e-6129457926307MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1130136RRTLQKN
Functional Description ? help Back to Top
Source Description
UniProtMay be involved in an oxidative stress-mediated signaling cascade that phosphorylates downstream MAP kinases MPK3 and MPK6. May suppress auxin signaling that promotes cell cycle. Functionally redundant to ANP2 and ANP3 in the positive regulation of cytokinesis. {ECO:0000269|PubMed:10717008, ECO:0000269|PubMed:12034900}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKM0831050.0KM083105.1 Brassica napus cultivar DH12075 mitogen-activated protein kinase kinase kinase 1.1 (MAPKKK1) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018435510.10.0PREDICTED: mitogen-activated protein kinase kinase kinase ANP1
SwissprotO220400.0ANP1_ARATH; Mitogen-activated protein kinase kinase kinase ANP1
TrEMBLA0A0U1XJX70.0A0A0U1XJX7_BRANA; Mitogen-activated protein kinase kinase kinase 1.1
TrEMBLA0A3P6F1660.0A0A3P6F166_BRAOL; Uncharacterized protein
STRINGBra018588.1-P0.0(Brassica rapa)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G08970.42e-86nuclear factor Y, subunit C9
Publications ? help Back to Top
  1. Kovtun Y,Chiu WL,Tena G,Sheen J
    Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants.
    Proc. Natl. Acad. Sci. U.S.A., 2000. 97(6): p. 2940-5
    [PMID:10717008]
  2. Krysan PJ,Jester PJ,Gottwald JR,Sussman MR
    An Arabidopsis mitogen-activated protein kinase kinase kinase gene family encodes essential positive regulators of cytokinesis.
    Plant Cell, 2002. 14(5): p. 1109-20
    [PMID:12034900]
  3. Lukowitz W,Roeder A,Parmenter D,Somerville C
    A MAPKK kinase gene regulates extra-embryonic cell fate in Arabidopsis.
    Cell, 2004. 116(1): p. 109-19
    [PMID:14718171]
  4. Takahashi Y,Soyano T,Kosetsu K,Sasabe M,Machida Y
    HINKEL kinesin, ANP MAPKKKs and MKK6/ANQ MAPKK, which phosphorylates and activates MPK4 MAPK, constitute a pathway that is required for cytokinesis in Arabidopsis thaliana.
    Plant Cell Physiol., 2010. 51(10): p. 1766-76
    [PMID:20802223]
  5. Sasabe M,Machida Y
    Regulation of organization and function of microtubules by the mitogen-activated protein kinase cascade during plant cytokinesis.
    Cytoskeleton (Hoboken), 2012. 69(11): p. 913-8
    [PMID:23027702]
  6. Christian M,Qi Y,Zhang Y,Voytas DF
    Targeted mutagenesis of Arabidopsis thaliana using engineered TAL effector nucleases.
    G3 (Bethesda), 2013. 3(10): p. 1697-705
    [PMID:23979944]
  7. Savatin DV, et al.
    The Arabidopsis NUCLEUS- AND PHRAGMOPLAST-LOCALIZED KINASE1-Related Protein Kinases Are Required for Elicitor-Induced Oxidative Burst and Immunity.
    Plant Physiol., 2014. 165(3): p. 1188-1202
    [PMID:24812107]
  8. Su SH,Krysan PJ
    A double-mutant collection targeting MAP kinase related genes in Arabidopsis for studying genetic interactions.
    Plant J., 2016. 88(5): p. 867-878
    [PMID:27490954]
  9. Gigli Bisceglia N,Savatin DV,Cervone F,Engelsdorf T,De Lorenzo G
    Loss of the Arabidopsis Protein Kinases ANPs Affects Root Cell Wall Composition, and Triggers the Cell Wall Damage Syndrome.
    Front Plant Sci, 2017. 8: p. 2234
    [PMID:29403509]
  10. Nishihama R,Banno H,Kawahara E,Irie K,Machida Y
    Possible involvement of differential splicing in regulation of the activity of Arabidopsis ANP1 that is related to mitogen-activated protein kinase kinase kinases (MAPKKKs).
    Plant J., 1997. 12(1): p. 39-48
    [PMID:9263451]