PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

C2H2

Protein Properties

Length: 262aa MW: 28660 Da PI: 5.601

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
RrC1925_p1	genome	MSU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13.5	0.00021	87	109	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C + F ++ L H++ H RrC1925_p1 87 FSCNYCQRKFYSSQALGGHQNAH 109 89*****************9988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.06E-6	83	114	No hit	No description
PROSITE profile	PS50157	11.427	87	114	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	89	109	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 262 aa Download sequence Send to blast
MMRPILDLEI EASSEHDHSD SASSQVASNL SPVGDDYKSI SLDLSLCFNN NNNNLDLESS 60 SLTLPISSTS EISNPEQQQP SVSKRVFSCN YCQRKFYSSQ ALGGHQNAHK RERTLAKRAM 120 RMGLAGVFPG RGSSSSYAAA ATAAALSCLP LHGSGNSNMT SFRTLGIRAH ASPHDLGITR 180 PTQETIIRNI ARFNQGYFSN FVPFLVEDDE AELLWPGSFR QRANEVAVEA VDGDLGERKV 240 DYLEVKQAVD MECSLPDLTL KL

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development. {ECO:0000269\|PubMed:24808098}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018453325.1	0.0	PREDICTED: zinc finger protein 4-like
Swissprot	Q39263	1e-121	ZFP4_ARATH; Zinc finger protein 4
TrEMBL	A0A3P6AU33	1e-168	A0A3P6AU33_BRACM; Uncharacterized protein
STRING	Bra039750.1-P	1e-164	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6672	26	43

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G66140.1	1e-112	zinc finger protein 4

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Joseph MP, et al. The Arabidopsis ZINC FINGER PROTEIN3 Interferes with Abscisic Acid and Light Signaling in Seed Germination and Plant Development. Plant Physiol., 2014. 165(3): p. 1203-1220 [PMID:24808098] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470]