PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

C2H2

Protein Properties

Length: 563aa MW: 58879.3 Da PI: 8.6779

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
RrC18685_p1	genome	MSU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17	1.6e-05	59	81	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H RrC18685_p1 59 FVCEICNKGFQRDQNLQLHRRGH 81 89*******************88 PP
2	zf-C2H2	13	0.0003	136	158	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ykC +C+k + +s+ k H + + RrC18685_p1 136 YKCDKCSKKYAVQSDWKAHSKIC 158 9******************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.21E-7	58	81	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.9E-5	58	81	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.017	59	81	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	59	81	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	61	81	IPR007087	Zinc finger, C2H2
SMART	SM00355	230	101	131	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	2.7E-4	124	157	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.21E-7	131	156	No hit	No description
SMART	SM00355	80	136	156	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009937	Biological Process	regulation of gibberellic acid mediated signaling pathway
GO:0010029	Biological Process	regulation of seed germination
GO:0010431	Biological Process	seed maturation
GO:0005634	Cellular Component	nucleus
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 563 aa Download sequence Send to blast
MAPVELENSS TVSGDASGVS STGNLNPPPK KKRNLPGMPD PGAEVIALSP KTLMATNRFV 60 CEICNKGFQR DQNLQLHRRG HNLPWKLRQR SAKDAVRKKV YVCPVSACVH HDPSRALGDL 120 TGIKKHFCRK HGEKKYKCDK CSKKYAVQSD WKAHSKICGT KEYRCDCGTL FSRKDSFITH 180 RAFCDVLAEE SAKNQTNKLY PQPELKSPPA AAAPPTSPPS VAPPNVSAET EPVKIASPSV 240 RSSSESPNPL EVIMEEAPRT IGFNVTSSVI SDDDRSGNNN CTPRTIGFNV TSSGLSGDHT 300 SNNNNNNGIY AGLFSSSTSS PSLYASSTPS TSLFAPPSSS MEPISLCLST NPSLYVGPTT 360 IQDPHPPPHF LTPLSLPPPQ PAMSATALLQ KAAQMGSTGS GGSLLRGLGI VSSTSSSMEL 420 SSHDLGLGLL PPCSSGGSGG SGLKELMMGN SCVFGPKQTT LDFLGLGRAV GNGSSNPVGG 480 GLSALLTSIG GGGGMDVFGT AGEFPGKDIG RSFESSSSSS SSVNFNHNFW FLLSAMMKQE 540 AIGVAGGVGG WAEAGVNAGL FSR

Sequence ? help Back to Top

Protein Sequence Length: 563 aa Download sequence Send to blast

MAPVELENSS TVSGDASGVS STGNLNPPPK KKRNLPGMPD PGAEVIALSP KTLMATNRFV  60
CEICNKGFQR DQNLQLHRRG HNLPWKLRQR SAKDAVRKKV YVCPVSACVH HDPSRALGDL  120
TGIKKHFCRK HGEKKYKCDK CSKKYAVQSD WKAHSKICGT KEYRCDCGTL FSRKDSFITH  180
RAFCDVLAEE SAKNQTNKLY PQPELKSPPA AAAPPTSPPS VAPPNVSAET EPVKIASPSV  240
RSSSESPNPL EVIMEEAPRT IGFNVTSSVI SDDDRSGNNN CTPRTIGFNV TSSGLSGDHT  300
SNNNNNNGIY AGLFSSSTSS PSLYASSTPS TSLFAPPSSS MEPISLCLST NPSLYVGPTT  360
IQDPHPPPHF LTPLSLPPPQ PAMSATALLQ KAAQMGSTGS GGSLLRGLGI VSSTSSSMEL  420
SSHDLGLGLL PPCSSGGSGG SGLKELMMGN SCVFGPKQTT LDFLGLGRAV GNGSSNPVGG  480
GLSALLTSIG GGGGMDVFGT AGEFPGKDIG RSFESSSSSS SSVNFNHNFW FLLSAMMKQE  540
AIGVAGGVGG WAEAGVNAGL FSR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-32	132	193	3	64	Zinc finger protein JACKDAW
5b3h_F	2e-32	132	193	3	64	Zinc finger protein JACKDAW
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	85	98	KLRQRSAKDAVRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor promoting the transition to germination by regulating light and hormonal signaling during seed maturation (PubMed:21571950). Acts as a positive regulator of phytochrome and/or gibberellin action (PubMed:21571950, PubMed:25035403). {ECO:0000269\|PubMed:21571950, ECO:0000269\|PubMed:25035403}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00592	DAP	Transfer from AT5G66730	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018459862.1	0.0	PREDICTED: protein indeterminate-domain 1-like
Swissprot	Q9LVQ7	0.0	IDD1_ARATH; Zinc finger protein ENHYDROUS
TrEMBL	R0EWK5	0.0	R0EWK5_9BRAS; Uncharacterized protein
STRING	Cagra.2007s0026.1.p	0.0	(Capsella grandiflora)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM155	28	306

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G66730.1	1e-163	C2H2-like zinc finger protein

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]