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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
RrC17636_p2 |
| Organism |
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| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
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| Family |
NAC |
| Protein Properties |
Length: 175aa MW: 20243.2 Da PI: 10.0136 |
| Description |
NAC family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| RrC17636_p2 | genome | MSU | View CDS |
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| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | NAM | 61.9 | 2e-19 | 10 | 95 | 51 | 128 |
NAM 51 vkaeekewyfFskrdkkyatgkrknr.atksgy......WkatgkdkevlskkgelvglkktLvfy..kgrapkgektdWvmheyrl 128
v+++ ++++fF k+ ++y++g+rk+r +t sg W++tgk+k+v+ +g ++g+kk +v+y ++ +k+e+++Wvmh+y+l
RrC17636_p2 10 VNKDGTSTFFFNKTVHAYPKGERKRRsITPSGLkdaslrWRKTGKTKPVMI-NGVQKGCKKFMVLYksAKKGSKPENSKWVMHQYHL 95
45567789******************6666554444445************.999***********44246667779********98 PP
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| Sequence ? help Back to Top |
| Protein Sequence Length: 175 aa
Download sequence Send
to blast |
MSLSKTFDSV NKDGTSTFFF NKTVHAYPKG ERKRRSITPS GLKDASLRWR KTGKTKPVMI 60
NGVQKGCKKF MVLYKSAKKG SKPENSKWVM HQYHLGREEA ETGEYVVSKI MYQQQQQGLE 120
NTQEASSSLV EKNPNYWDFD MSYGNCMKLD KQVILLRIFL QFASEDSIMN CLEWI
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| Functional Description ? help
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| Source |
Description |
| UniProt | Transcription factor regulating the transcriptional activation response to gamma irradiation (PubMed:19549833). Required for stem-cell death induced by UVB or by gamma irradiation (PubMed:20634150). Not required for ATM activation, but participates in pathways governed by both ATM and ATR sensor kinases (PubMed:19549833). Involved in DNA damage response (DDR) system that regulates cell cycle arrest (PubMed:24399300). Functional homolog of animal p53 (PubMed:24736489). Regulates SMR5 and SMR7 transcription (PubMed:24399300). Regulates DNA repair and cytokinin signaling separately and plays a key role in controlling lateral root formation under genotoxic stress. {ECO:0000269|PubMed:19549833, ECO:0000269|PubMed:20634150, ECO:0000269|PubMed:24399300, ECO:0000305|PubMed:24736489}. |
| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: Not induced by zeocin or ionizing radiation treatment. {ECO:0000269|PubMed:23907539}. |
| Publications
? help Back to Top |
- Yi D, et al.
The Arabidopsis SIAMESE-RELATED cyclin-dependent kinase inhibitors SMR5 and SMR7 regulate the DNA damage checkpoint in response to reactive oxygen species.
Plant Cell, 2014. 26(1): p. 296-309
[PMID:24399300] - Biever JJ,Brinkman D,Gardner G
UV-B inhibition of hypocotyl growth in etiolated Arabidopsis thaliana seedlings is a consequence of cell cycle arrest initiated by photodimer accumulation.
J. Exp. Bot., 2014. 65(11): p. 2949-61
[PMID:24591052] - Hu Z,Cools T,Kalhorzadeh P,Heyman J,De Veylder L
Deficiency of the Arabidopsis helicase RTEL1 triggers a SOG1-dependent replication checkpoint in response to DNA cross-links.
Plant Cell, 2015. 27(1): p. 149-61
[PMID:25595823] - Chen P,Umeda M
DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana.
Genes Cells, 2015. 20(8): p. 636-46
[PMID:26033196] - Sjogren CA,Bolaris SC,Larsen PB
Aluminum-Dependent Terminal Differentiation of the Arabidopsis Root Tip Is Mediated through an ATR-, ALT2-, and SOG1-Regulated Transcriptional Response.
Plant Cell, 2015. 27(9): p. 2501-15
[PMID:26320227] - Yoshiyama KO
SOG1: a master regulator of the DNA damage response in plants.
Genes Genet. Syst., 2016. 90(4): p. 209-16
[PMID:26617076] - Weimer AK, et al.
The plant-specific CDKB1-CYCB1 complex mediates homologous recombination repair in Arabidopsis.
EMBO J., 2016. 35(19): p. 2068-2086
[PMID:27497297] - Davis OM,Ogita N,Inagaki S,Takahashi N,Umeda M
DNA damage inhibits lateral root formation by up-regulating cytokinin biosynthesis genes in Arabidopsis thaliana.
Genes Cells, 2016. 21(11): p. 1195-1208
[PMID:27658920] - Pedroza-García JA, et al.
Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis.
Plant Physiol., 2017. 173(3): p. 1735-1749
[PMID:28153919] - Horvath BM, et al.
Arabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control.
EMBO J., 2017. 36(9): p. 1261-1278
[PMID:28320736] - Sjogren CA,Larsen PB
SUV2, which encodes an ATR-related cell cycle checkpoint and putative plant ATRIP, is required for aluminium-dependent root growth inhibition in Arabidopsis.
Plant Cell Environ., 2017. 40(9): p. 1849-1860
[PMID:28556304] - Yoshiyama KO,Kaminoyama K,Sakamoto T,Kimura S
Increased Phosphorylation of Ser-Gln Sites on SUPPRESSOR OF GAMMA RESPONSE1 Strengthens the DNA Damage Response in Arabidopsis thaliana.
Plant Cell, 2017. 29(12): p. 3255-3268
[PMID:29208704] - Johnson RA, et al.
SUPPRESSOR OF GAMMA RESPONSE1 Links DNA Damage Response to Organ Regeneration.
Plant Physiol., 2018. 176(2): p. 1665-1675
[PMID:29222192] - Ogita N, et al.
Identifying the target genes of SUPPRESSOR OF GAMMA RESPONSE 1, a master transcription factor controlling DNA damage response in Arabidopsis.
Plant J., 2018. 94(3): p. 439-453
[PMID:29430765] - Cao X, et al.
Roles of MSH2 and MSH6 in cadmium-induced G2/M checkpoint arrest in Arabidopsis roots.
Chemosphere, 2018. 201: p. 586-594
[PMID:29533809]
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