PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

HSF

Protein Properties

Length: 267aa MW: 31284.6 Da PI: 6.0014

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
RrC14908_p1	genome	MSU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	105.6	4e-33	27	118	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 Fl k++ei+ed+++++++sw++ g+sfvv+d ++f++ +Lp++Fkhsnf+SF+RQLn+YgF+k++ ++ weF+++ F g+++ll+ ik RrC14908_p1 27 FLIKTFEIVEDPSTDHIVSWNRGGTSFVVWDLHSFSTFLLPRHFKHSNFSSFIRQLNTYGFRKIEADR---------WEFANDGFLLGQRQLLKFIK 114 9**************************************************************999.........****************** PP XXXX CS HSF_DNA-bind 99 rkks 102 r++s RrC14908_p1 115 RRAS 118 *975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	5.2E-35	21	110	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	8.0E-54	23	116	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	3.4E-33	23	116	IPR011991	Winged helix-turn-helix DNA-binding domain
PRINTS	PR00056	7.2E-19	27	50	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	1.8E-28	27	116	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	7.2E-19	65	77	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	66	90	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	7.2E-19	78	90	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009408	Biological Process	response to heat
GO:0009644	Biological Process	response to high light intensity
GO:0032268	Biological Process	regulation of cellular protein metabolic process
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 267 aa Download sequence Send to blast
MNPFQLQEGD PPPKPVEGLH EIGPPPFLIK TFEIVEDPST DHIVSWNRGG TSFVVWDLHS 60 FSTFLLPRHF KHSNFSSFIR QLNTYGFRKI EADRWEFAND GFLLGQRQLL KFIKRRASFG 120 SSSPSINDPC TELRREKQLL MMELVCLRQQ QQTTRRYIKA MEQRIEAAER KQRQMMSFLA 180 RAMQSPSFLH QLLKQRDMRL KEIEDEAAER ERCSPMSELE TLALEMQGYG KQKNVKEEED 240 MVVERELDDG FWEELLSNES LASTSSY

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ldu_A	1e-22	25	118	18	122	Heat shock factor protein 1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	109	115	LKFIKRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AL049711	1e-48	AL049711.3 Arabidopsis thaliana DNA chromosome 3, BAC clone F4F15.
GenBank	CP002686	1e-48	CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018477312.1	0.0	PREDICTED: heat stress transcription factor A-7a isoform X1
Refseq	XP_018477314.1	0.0	PREDICTED: heat stress transcription factor A-7a isoform X2
Swissprot	Q9SV12	1e-145	HFA7A_ARATH; Heat stress transcription factor A-7a
TrEMBL	A0A397ZIY8	0.0	A0A397ZIY8_BRACM; Uncharacterized protein
STRING	Bo4g125760.1	1e-176	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1256	28	99

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G51910.1	1e-147	heat shock transcription factor A7A

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Guan Q,Yue X,Zeng H,Zhu J The protein phosphatase RCF2 and its interacting partner NAC019 are critical for heat stress-responsive gene regulation and thermotolerance in Arabidopsis. Plant Cell, 2014. 26(1): p. 438-53 [PMID:24415771] Nie S,Yue H,Xing D A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance. Plant Physiol., 2016. [PMID:26099269]