PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID RrC11711_p1
Organism
Raphanus raphanistrum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family E2F/DP
Protein Properties Length: 345aa    MW: 38922.8 Da    PI: 6.958
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
RrC11711_p1genomeMSUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.21e-26127192171
      E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                  r+++sL+llt+kf++l+ ++e+g ++ln++a+ L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  RrC11711_p1 127 RYDSSLGLLTKKFVNLIIEAEDGSLDLNHCADVL---EV--QKRRIYDITNVLEGIGLIEKTTKNHIRWKG 192
                  6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.5E-28123194IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.2E-32127192IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.95E-17127190IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023196.6E-24129192IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146602.53E-25200288No hitNo description
PfamPF164218.3E-18212285IPR032198E2F transcription factor, CC-MB domain
SuperFamilySSF1440741.39E-17219287No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 345 aa     Download sequence    Send to blast
MAATSKSGED PTLSYTHPSP FSFDLLQSLD PRHTPSSTNR TFSVSESLPI TQSPQIQAQS  60
YSPITHQFKN RNIPGETIDI AKVIVKQESP LENLKRGNNS KVTKLSKATV KREAQQLGGP  120
NGSNNCRYDS SLGLLTKKFV NLIIEAEDGS LDLNHCADVL EVQKRRIYDI TNVLEGIGLI  180
EKTTKNHIRW KGADNLGHLE LGDQISRLKT RTLLRSVRQT HRYMFMTEED ITSLPCFQNK  240
TLLAIKAPTA SYIEVPDPDE VLSFPQRQYR MVIRSRMGPI DVYLLSKYKG ENSRETNESD  300
QNTPSGVDTP SLKIVTSDTD LKTDYWFESE SEVSLTHLWN TFTEN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-23127193774PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankJN9429731e-122JN942973.1 Brassica juncea E2F transcription factor (E2Fc) mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018488549.10.0PREDICTED: transcription factor E2FC-like
SwissprotQ9FV701e-159E2FC_ARATH; Transcription factor E2FC
TrEMBLA0A0D3DJW71e-175A0A0D3DJW7_BRAOL; Uncharacterized protein
TrEMBLA0A3N6S7721e-175A0A3N6S772_BRACR; Uncharacterized protein
STRINGBo8g016640.11e-175(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.21e-162E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]