PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Amygdaleae; Prunus

Family

ERF

Protein Properties

Length: 289aa MW: 31688.4 Da PI: 6.3624

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Prupe.6G004400.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	59.1	1e-18	31	81	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.psengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +++ GVr+++ +g+WvAeI+d k+ r +lg+f taeeAa+a+++a+ l+g Prupe.6G004400.1.p 31 CKFVGVRQRP-SGKWVAEIKDtT----KKIRMWLGTFETAEEAARAYDEAAYLLRG 81 799*****.7*****33....36********************99997 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	6.27E-32	31	88	No hit	No description
Pfam	PF00847	3.0E-13	31	81	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	20.455	32	89	IPR001471	AP2/ERF domain
SMART	SM00380	1.1E-36	32	95	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.7E-28	32	89	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.64E-20	32	90	IPR016177	DNA-binding domain
PRINTS	PR00367	5.1E-8	33	44	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.1E-8	55	71	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0000302	Biological Process	response to reactive oxygen species
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009723	Biological Process	response to ethylene
GO:0035865	Biological Process	cellular response to potassium ion
GO:0048528	Biological Process	post-embryonic root development
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 289 aa Download sequence Send to blast
MEEEHEEAPK QQKENGVSVS ANKQSKLKTK CKFVGVRQRP SGKWVAEIKD TTKKIRMWLG 60 TFETAEEAAR AYDEAAYLLR GSNTRTNFST HVPSNSPLSL KIRNLLNHKK SLNLKQKQSP 120 PPTPNSSLKS TPIAATTTRI SSSSSICSGN IQAFSDTSSA NCNANSSSPL PCYKSQDIQA 180 FDDAYRPDLS NCIGELQPAM FHLDQSWPFL AGFDQLPLTH EGMDLTKGIG NVAAAEAEVA 240 EFERLKVERQ ISASIYAMNG GNEYVDNEYD GSDALWDLPT LSQLFCLG*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	7e-16	33	92	3	63	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
5wx9_A	1e-15	32	88	14	71	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the symbiotic nodule signaling pathway in response to rhizobial stimulation. Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation, and nodule development. May coordinate these processes (PubMed:28503742, PubMed:28028038, PubMed:28068194). Functions downstream of the CCAMK-CYCLOPS complex (PubMed:28503742, PubMed:28028038). Probably not involved in arbuscular mycorrhizal (AM) symbiosis (PubMed:28068194). {ECO:0000269\|PubMed:28028038, ECO:0000269\|PubMed:28068194, ECO:0000269\|PubMed:28503742}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00521	DAP	Transfer from AT5G19790	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Prupe.6G004400.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in nodules 7 days after rhizobial inoculation. {ECO:0000269\|PubMed:28028038, ECO:0000269\|PubMed:28503742}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007206809.1	0.0	ethylene-responsive transcription factor RAP2-11
Swissprot	A0A1X9PY88	3e-75	ERN1_LOTJA; Ethylene-responsive transcription factor ERN1
TrEMBL	M5WFH4	0.0	M5WFH4_PRUPE; Uncharacterized protein
STRING	EMJ08008	0.0	(Prunus persica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3341	30	69

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G19790.1	1e-30	related to AP2 11

Link Out ? help Back to Top
Phytozome	Prupe.6G004400.1.p
Entrez Gene	18771957

Publications ? help Back to Top
Yano K, et al. Function and evolution of a Lotus japonicus AP2/ERF family transcription factor that is required for development of infection threads. DNA Res., 2017. 24(2): p. 193-203 [PMID:28028038] Kawaharada Y,James EK,Kelly S,Sandal N,Stougaard J The Ethylene Responsive Factor Required for Nodulation 1 (ERN1) Transcription Factor Is Required for Infection-Thread Formation in Lotus japonicus. Mol. Plant Microbe Interact., 2017. 30(3): p. 194-204 [PMID:28068194] Cerri MR, et al. The ERN1 transcription factor gene is a target of the CCaMK/CYCLOPS complex and controls rhizobial infection in Lotus japonicus. New Phytol., 2017. 215(1): p. 323-337 [PMID:28503742]