PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pp3c2_24250V3.1.p
Organism
Physcomitrella patens
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrella
Family NF-X1
Protein Properties Length: 980aa    MW: 107323 Da    PI: 8.4668
Description NF-X1 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pp3c2_24250V3.1.pgenomeCOSMOSSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-NF-X117.31e-05240258120
           zf-NF-X1   1 CGkHkCqklCHeGpCppCpq 20 
                        CG H C  lCH+GpCp Cpq
  Pp3c2_24250V3.1.p 240 CG-HECVLLCHPGPCPTCPQ 258
                        **.****************8 PP
2zf-NF-X123.89.8e-08292311120
           zf-NF-X1   1 CGkHkCqklCHeGpCppCpq 20 
                        CGkHkC+  CH G+CppC++
  Pp3c2_24250V3.1.p 292 CGKHKCENACHDGDCPPCSK 311
                        ******************85 PP
3zf-NF-X121.84.1e-07479497119
           zf-NF-X1   1 CGkHkCqklCHeGpCppCp 19 
                        CG+HkC ++CH+G C pCp
  Pp3c2_24250V3.1.p 479 CGNHKCPAPCHRGLCAPCP 497
                        ******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE patternPS013590123194IPR019786Zinc finger, PHD-type, conserved site
CDDcd060081.32E-6228276No hitNo description
SMARTSM004380.0035240258IPR000967Zinc finger, NF-X1-type
PfamPF014220.017240257IPR000967Zinc finger, NF-X1-type
CDDcd060088.63E-10282330No hitNo description
SMARTSM004385.6E-4292311IPR000967Zinc finger, NF-X1-type
PfamPF014224.9E-6292310IPR000967Zinc finger, NF-X1-type
CDDcd060081.88E-9335382No hitNo description
SMARTSM004381.4345364IPR000967Zinc finger, NF-X1-type
CDDcd060088.82E-9389438No hitNo description
SMARTSM004380.11399419IPR000967Zinc finger, NF-X1-type
PfamPF014220.29399418IPR000967Zinc finger, NF-X1-type
CDDcd060082.92E-7442490No hitNo description
SMARTSM004380.19452471IPR000967Zinc finger, NF-X1-type
PfamPF014220.0083452470IPR000967Zinc finger, NF-X1-type
CDDcd060086.30E-11469517No hitNo description
SMARTSM004380.0014479498IPR000967Zinc finger, NF-X1-type
PfamPF014229.0E-5479497IPR000967Zinc finger, NF-X1-type
SMARTSM00438210536557IPR000967Zinc finger, NF-X1-type
SMARTSM00438130565610IPR000967Zinc finger, NF-X1-type
PfamPF0142227565574IPR000967Zinc finger, NF-X1-type
PfamPF014223.8647657IPR000967Zinc finger, NF-X1-type
SMARTSM004380.025744762IPR000967Zinc finger, NF-X1-type
PfamPF014220.98746761IPR000967Zinc finger, NF-X1-type
SMARTSM004385.4807829IPR000967Zinc finger, NF-X1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000122Biological Processnegative regulation of transcription from RNA polymerase II promoter
GO:0007623Biological Processcircadian rhythm
GO:0009651Biological Processresponse to salt stress
GO:0009908Biological Processflower development
GO:0010310Biological Processregulation of hydrogen peroxide metabolic process
GO:0042335Biological Processcuticle development
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:2000037Biological Processregulation of stomatal complex patterning
GO:0005634Cellular Componentnucleus
GO:0016021Cellular Componentintegral component of membrane
GO:0000977Molecular FunctionRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000987Molecular Functioncore promoter proximal region sequence-specific DNA binding
GO:0001078Molecular Functiontranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 980 aa     Download sequence    Send to blast
MIHARAMDKG SVSHAAGTSS QGRNAWNTPL RNQPQSQASA AIKMPVKNPP LSFTNQPALA  60
DPIYSSSDED SESGGEGGAR GRDVDALESA IMADYPTTED IDDTGLTKIR SLLLARRSGA  120
TSCLICLERV RATDPVWDCK AGCHVIFHLI CIQSWARQAL GAAAIRSLGQ LSGQHFPAAQ  180
AEAEDKACWH CPKCRTDYSK SELPREYRCF CGKQEHPVHD PWLAPHTCGE RCGRALPSKC  240
GHECVLLCHP GPCPTCPQLL KFSCFCGAES KMRRCGHSKF SCGRECKKVL SCGKHKCENA  300
CHDGDCPPCS KTAVHKCQCG KTSAIRACAE SNFRCENPCG RQLSCQKHCC QRGCHSGPCG  360
DCYLTGKRSC PCGKVEHKGV PCDVVIPTCG STCEKVLPCQ IHRCSERCHY GSCKEVCRVV  420
LVKSCRCGSL KKEVPCHQEL LCERKCQRMK DCGRHACKRR CCDGDCPLCS EVCGRRLKCG  480
NHKCPAPCHR GLCAPCPINV QISCACGATC IQVPCGTERT QRPPRCVKLC SISPKCNHGS  540
NCKPHRCHYG ACPECQLPCM TLLPCGHNCK ERCHGAKPVP NPDYTYKTKK KKPIHDGSAS  600
IGEPCPACSE RIVKKCLGQH QGSERTMVCS QSAEFRCSKL CGNPLACGNH ICRNSCHFVT  660
IPRIVAGEEV YVKQVVVMPS GIDLAEPTDE PERVWGKYGS SPLNEKGNSN NLVQETSTQP  720
DNVKVVDSCE QCRLPCQKKR FLRCPHPCTQ ICHIGDCKPC KAVLKRACHC EALVQSFECT  780
AFNSVSDKER AKLLSCGGPC HKKLPNCSHL CPDICHPGIC PTAADSCRKK VTVRCACQRL  840
KKEWLCCDAQ AALPKGSQKS AVFGVGLLPC DQECSRLAAE RREKEETELL RHRKSKEPEM  900
NTAPVKVPKK RRGRNLDDTT KPSAFKENIV KAGRWIMIGF LVVGAFLVLV YGYKGLLALS  960
RWMDARDAVK PRRRMSGGF*
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Constitutively expressed in mesophyll and guard cells. {ECO:0000269|PubMed:22073231}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcriptional regulator. May mediate E2- or E3-dependent ubiquitination. Required to gate light sensitivity during the night. Regulates the speed of the clock by acting in the feedback loop between CCA1, LHY and APRR1/TOC1. Promotes the expression of CCA1 at night but not by days. This activational effect is enhanced by interaction with ADO1/ZTL. Association with ADO1/ZTL is not leading to the degradation of NFXL2. Confers sensitivity to osmotic stress such as high salinity. Prevents H(2)O(2) production and abscisic acid accumulation. Part of a regulatory network that integrates the biosynthesis and action of abscisic acid, reactive oxygen species and cuticle components. {ECO:0000269|PubMed:16905136, ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:21429190, ECO:0000269|PubMed:22073231, ECO:0000269|PubMed:22516817}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Circadian-regulation with a peak of expression at or before dawn. Not regulated by biotic and abiotic stresses, by light and nutrient conditions or upon treatment with elicitors, chemicals, abscisic acid or phytohormones. {ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:22073231}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024402753.10.0NF-X1-type zinc finger protein NFXL2-like
SwissprotQ9FFK80.0NFXL2_ARATH; NF-X1-type zinc finger protein NFXL2
TrEMBLA0A2K1L2V00.0A0A2K1L2V0_PHYPA; Uncharacterized protein
STRINGPP1S135_24V6.10.0(Physcomitrella patens)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP63251718
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G05660.10.0sequence-specific DNA binding transcription factors;zinc ion binding;sequence-specific DNA binding transcription factors