PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pp3c12_4630V3.2.p

Common Name

PHYPADRAFT_195760

Organism

Physcomitrella patens

Taxonomic ID

3218

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrella

Family

bHLH

Protein Properties

Length: 239aa MW: 26444.8 Da PI: 6.7704

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pp3c12_4630V3.2.p	genome	COSMOSS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	32.4	1.6e-10	79	125	5	54
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 + rE+ RRdr+N++f L l + + +K +Ka+iL Av+ + +L Pp3c12_4630V3.2.p 79 KACREKMRRDRLNDRFLDLSAALEPG---RPPKTDKATILSDAVRILTQL 125 678********************8...89************99988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.31E-12	67	141	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	12.182	74	125	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.11E-7	78	130	No hit	No description
Pfam	PF00010	5.0E-8	79	125	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	7.1E-8	80	131	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	3.2E-11	81	147	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000006	anatomy	plant protoplast
PO:0025017	anatomy	plant spore
PO:0030003	anatomy	protonema
PO:0030018	anatomy	gametophore

Sequence ? help Back to Top
Protein Sequence Length: 239 aa Download sequence Send to blast
MMSSPSNTSK WMSYLAENLL AEEEVQPSNP FFWCTTQQPV EQIDCSIDNE CSKGESDVPE 60 KSCSRKRSRE EGSSGSGNKA CREKMRRDRL NDRFLDLSAA LEPGRPPKTD KATILSDAVR 120 ILTQLRAEAQ GLTESNNQLR ETIKDLKNEK NELREEKTRL KADKERLEQQ VKAMTIPAGY 180 MPHPAALHAA VAAFAAQTQA ASNKAAQIAG YPGMAMWQWM PPAAVDTSQD HVLRPPVA*

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Ppa.4243	0.0	gametophore\| protonema

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Widely expressed throughout development, mostly in vasculatures. {ECO:0000269\|PubMed:17028341}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024390784.1	1e-178	transcription factor ILR3-like
Refseq	XP_024390785.1	1e-178	transcription factor ILR3-like
Swissprot	Q9FH37	6e-76	ILR3_ARATH; Transcription factor ILR3
TrEMBL	A9TJS4	1e-177	A9TJS4_PHYPA; Predicted protein
STRING	PP1S246_45V6.3	1e-177	(Physcomitrella patens)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	3e-40	bHLH family protein

Link Out ? help Back to Top
Phytozome	Pp3c12_4630V3.2.p
Entrez Gene	5942046

Publications ? help Back to Top
Rensing SA, et al. The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants. Science, 2008. 319(5859): p. 64-9 [PMID:18079367] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]