PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus

Family

MYB

Protein Properties

Length: 531aa MW: 58859.2 Da PI: 8.0848

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Potri.006G085600.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	53.2	6.6e-17	60	106	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT+eEde l av+ + g++Wk+Ia+ ++ R++ qc +rwqk+l Potri.006G085600.1 60 KGGWTPEEDETLRTAVATYKGKSWKKIAEFFP-DRSEVQCLHRWQKVL 106 688***************************.**********986 PP
2	Myb_DNA-binding	61.9	1.3e-19	112	158	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEd+++v++v+++G+ W+ Ia+ ++ gR +kqc++rw+++l Potri.006G085600.1 112 KGPWTQEEDDKIVELVAKYGPTKWSVIAKALP-GRIGKQCRERWHNHL 158 79****************************.***********97 PP
3	Myb_DNA-binding	54.9	2e-17	164	207	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +++WT eE++ l +a++ +G++ W+ Ia+ ++ gRt++++k++w++ Potri.006G085600.1 164 KDAWTLEEELALMNAHRIYGNK-WAEIAKVLP-GRTDNSIKNHWNS 207 679*****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	16.09	55	106	IPR017930	Myb domain
SMART	SM00717	4.9E-15	59	108	IPR001005	SANT/Myb domain
Pfam	PF00249	8.4E-16	60	106	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	3.23E-15	61	116	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	9.2E-23	62	114	IPR009057	Homeodomain-like
CDD	cd00167	2.04E-13	63	106	No hit	No description
PROSITE profile	PS51294	32.543	107	162	IPR017930	Myb domain
SuperFamily	SSF46689	3.67E-32	109	205	IPR009057	Homeodomain-like
SMART	SM00717	1.7E-18	111	160	IPR001005	SANT/Myb domain
Pfam	PF00249	1.1E-18	112	158	IPR001005	SANT/Myb domain
CDD	cd00167	6.12E-16	114	158	No hit	No description
Gene3D	G3DSA:1.10.10.60	5.2E-28	115	161	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	1.7E-23	162	213	IPR009057	Homeodomain-like
PROSITE profile	PS51294	22.728	163	213	IPR017930	Myb domain
SMART	SM00717	1.2E-16	163	211	IPR001005	SANT/Myb domain
Pfam	PF00249	1.2E-15	164	207	IPR001005	SANT/Myb domain
CDD	cd00167	1.29E-12	166	209	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 531 aa Download sequence Send to blast
MDELKIEERC LENKQLTPAS SSSQSEEGSG SAILKSPGVY SPATVSPTNR RTTGPIRRAK 60 GGWTPEEDET LRTAVATYKG KSWKKIAEFF PDRSEVQCLH RWQKVLDPEL VKGPWTQEED 120 DKIVELVAKY GPTKWSVIAK ALPGRIGKQC RERWHNHLNP DIKKDAWTLE EELALMNAHR 180 IYGNKWAEIA KVLPGRTDNS IKNHWNSSLK KKLDFYLSTG KLPPISKNGF QNGTKDTNKS 240 AVMKTMKESD SAAQTSSGTT DICKLDEDGK DQLESTLVLD VAASSSVLPN EYADSVDLSC 300 CDSESQQKFE DHQDKGIGSG LQFDRSTYGS LYYEPPLVEQ LDSYPSNMGS VQHENNSCPV 360 SSPIIFFTPP CVKSRDLSAQ SPESILRIAA MSFPNTPSIF RKRKTAQVDL LPSKIGKVGE 420 ETVKDRLDMS VEHEKIENTL EKTAAQDGSL CESPASLGNG TIRPNDKPFN ASPPYRLRSK 480 RTAVFKSVER QLEFTFEKGR SDGTKPTRLS VKRGSPVSED CSRATKMGVT *

Sequence ? help Back to Top

Protein Sequence Length: 531 aa Download sequence Send to blast

MDELKIEERC LENKQLTPAS SSSQSEEGSG SAILKSPGVY SPATVSPTNR RTTGPIRRAK  60
GGWTPEEDET LRTAVATYKG KSWKKIAEFF PDRSEVQCLH RWQKVLDPEL VKGPWTQEED  120
DKIVELVAKY GPTKWSVIAK ALPGRIGKQC RERWHNHLNP DIKKDAWTLE EELALMNAHR  180
IYGNKWAEIA KVLPGRTDNS IKNHWNSSLK KKLDFYLSTG KLPPISKNGF QNGTKDTNKS  240
AVMKTMKESD SAAQTSSGTT DICKLDEDGK DQLESTLVLD VAASSSVLPN EYADSVDLSC  300
CDSESQQKFE DHQDKGIGSG LQFDRSTYGS LYYEPPLVEQ LDSYPSNMGS VQHENNSCPV  360
SSPIIFFTPP CVKSRDLSAQ SPESILRIAA MSFPNTPSIF RKRKTAQVDL LPSKIGKVGE  420
ETVKDRLDMS VEHEKIENTL EKTAAQDGSL CESPASLGNG TIRPNDKPFN ASPPYRLRSK  480
RTAVFKSVER QLEFTFEKGR SDGTKPTRLS VKRGSPVSED CSRATKMGVT *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	1e-69	59	213	5	159	MYB PROTO-ONCOGENE PROTEIN
1h89_C	1e-69	59	213	5	159	MYB PROTO-ONCOGENE PROTEIN
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Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed both in proliferating and maturing stages of leaves. {ECO:0000269\|PubMed:26069325}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250\|UniProtKB:Q94FL9, ECO:0000269\|PubMed:26069325}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00482	DAP	Transfer from AT5G02320	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Potri.006G085600.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by ethylene and salicylic acid (SA). {ECO:0000269\|PubMed:16463103}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ567344	0.0	AJ567344.1 Populus tremula x Populus tremuloides mRNA for MYB transcription factor R3 type (myb gene).

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002308158.3	0.0	transcription factor MYB3R-5
Refseq	XP_024460215.1	0.0	transcription factor MYB3R-5
Swissprot	Q6R032	1e-172	MB3R5_ARATH; Transcription factor MYB3R-5
TrEMBL	A0A2K1ZZ16	0.0	A0A2K1ZZ16_POPTR; Uncharacterized protein
STRING	POPTR_0006s08570.1	0.0	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF6616	34	49
Representative plant	OGRP5	17	1784

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G02320.2	1e-168	myb domain protein 3r-5

Link Out ? help Back to Top
Phytozome	Potri.006G085600.1
Entrez Gene	7454926

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Chen P, et al. Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage. Nat Commun, 2017. 8(1): p. 635 [PMID:28935922]