PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus

Family

CAMTA

Protein Properties

Length: 1105aa MW: 124723 Da PI: 5.6164

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Potri.005G075100.2	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	177.1	2.3e-55	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenp 92 ++ ++rwl++ ei++iL n+++++++ e+++ p+sgsl+L++rk++ryfrkDG++w+kkkdgktv+E+he+LK g+v+vl+cyYah+e+n+ Potri.005G075100.2 20 VEAQNRWLRPAEIVEILSNYQRFRIAPEPAHMPPSGSLFLFDRKVLRYFRKDGHNWRKKKDGKTVKEAHERLKSGSVDVLHCYYAHGEDNE 110 6679************************************************************************************* PP CG-1 93 tfqrrcywlLeeelekivlvhylevk 118 +fqrr+yw+Leeel++ivlvhy+evk Potri.005G075100.2 111 NFQRRSYWMLEEELSHIVLVHYREVK 136 *********************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	81.374	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	2.1E-75	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	1.2E-48	21	134	IPR005559	CG-1 DNA-binding domain
Gene3D	G3DSA:2.60.40.10	9.4E-5	522	609	IPR013783	Immunoglobulin-like fold
Pfam	PF01833	1.4E-5	523	606	IPR002909	IPT domain
SuperFamily	SSF81296	2.49E-15	523	609	IPR014756	Immunoglobulin E-set
PROSITE profile	PS50297	19.041	694	827	IPR020683	Ankyrin repeat-containing domain
Gene3D	G3DSA:1.25.40.20	1.5E-17	703	819	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	9.86E-13	704	815	No hit	No description
SuperFamily	SSF48403	2.95E-16	710	817	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	4.7E-7	728	818	IPR020683	Ankyrin repeat-containing domain
SMART	SM00248	0.011	756	785	IPR002110	Ankyrin repeat
PROSITE profile	PS50088	9.778	756	788	IPR002110	Ankyrin repeat
SMART	SM00248	930	795	824	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	1.12E-7	926	980	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	2	929	951	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	8.206	932	959	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.0046	932	950	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.0039	952	974	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.597	953	977	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	2.3E-4	955	974	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0045944	Biological Process	positive regulation of transcription from RNA polymerase II promoter
GO:0005634	Cellular Component	nucleus
GO:0001077	Molecular Function	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0005515	Molecular Function	protein binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 1105 aa Download sequence Send to blast
MADSRRYPLG NQLDIQQILV EAQNRWLRPA EIVEILSNYQ RFRIAPEPAH MPPSGSLFLF 60 DRKVLRYFRK DGHNWRKKKD GKTVKEAHER LKSGSVDVLH CYYAHGEDNE NFQRRSYWML 120 EEELSHIVLV HYREVKGTRT NFNRIKEYEE PIPYSQETKD MMPNSEMDTS VSSSFRSNGY 180 QVPTGTTDST SMNSALASEY EDAESGYNNQ ASSRFNSFLE VQRPAMEKMD TGGYQGKMPA 240 VPVMEFISPA QVDTAKDTIG TEPASEPQKV FDLPSWEDVL ENCSRGIESV PFQTTLLSQV 300 DTVGVIPKQE DILEKFLANS FDKRQGMVGV IPKQEDILEK FLTNSFDRSQ DIGSHLLDQE 360 AWQTIEGGYS HRPKWSLDQK LHLDSDLTAR FHDQQLDSGN FINTFEPFCA QENDNHIQND 420 LQIQPANSDH GMTLDEKSIY STSMKQHILD DSRTEGLKKL DSFTRWMSKE LEDVDQPHLQ 480 SSSGTYWISA ESENVVDADN PSHGHLDTYT LGPSLSQDQL FSIIDFSPNW AYAGTEIKIL 540 VMGRFLKSRE EAENFKWSIM FGEVEVPAET IADGILRCTT PSHKAGRVPF YVTCSNRVAC 600 SEVREFEYRL SHVQDITYNY INIATEDLHM RLAKLLSLSS AFPSKYDSSD VDEISQLSNK 660 ISSLLKEGNE TWDQMLKLTS LEGFSSEKLK DQLLQKALKE QLHEWLLQKV AEGGKGPSVL 720 DEGGQGVLHF AAALGYEWAL EPTIVAGVSV NFRDVNGWTA LHWAASYGRE RTVASLIHLG 780 AAPGALTDPT PKYPTGRTPA DLASANGHKG ISGFLAESAL SAHLSSLNLE KQDGDAAESS 840 GIPASLTVSD CNETPVKDAD IPIGLSLKDS LAAVCNATQA AARIHQVFRV QSFQKKQLKE 900 YGDDKFGMSH ERALSLIAVK SQKAGQYDEP VHAAIRIQNK FRGWKGRKEF LIIRQRIVKI 960 QAHVRGHQVR KNYRKIIWSV GILDKIILRW RRKGSGLRGF KSEALTEGSS MQVVSTKDDD 1020 DDFLKEGRKQ TEERSQIALA RVKSMHQHPE AREQYHRLRN VVAEIQETKA MYEWANNSEA 1080 MVEFDDLINL ETLWDGDTFL PTDS*

Sequence ? help Back to Top

Protein Sequence Length: 1105 aa Download sequence Send to blast

MADSRRYPLG NQLDIQQILV EAQNRWLRPA EIVEILSNYQ RFRIAPEPAH MPPSGSLFLF  60
DRKVLRYFRK DGHNWRKKKD GKTVKEAHER LKSGSVDVLH CYYAHGEDNE NFQRRSYWML  120
EEELSHIVLV HYREVKGTRT NFNRIKEYEE PIPYSQETKD MMPNSEMDTS VSSSFRSNGY  180
QVPTGTTDST SMNSALASEY EDAESGYNNQ ASSRFNSFLE VQRPAMEKMD TGGYQGKMPA  240
VPVMEFISPA QVDTAKDTIG TEPASEPQKV FDLPSWEDVL ENCSRGIESV PFQTTLLSQV  300
DTVGVIPKQE DILEKFLANS FDKRQGMVGV IPKQEDILEK FLTNSFDRSQ DIGSHLLDQE  360
AWQTIEGGYS HRPKWSLDQK LHLDSDLTAR FHDQQLDSGN FINTFEPFCA QENDNHIQND  420
LQIQPANSDH GMTLDEKSIY STSMKQHILD DSRTEGLKKL DSFTRWMSKE LEDVDQPHLQ  480
SSSGTYWISA ESENVVDADN PSHGHLDTYT LGPSLSQDQL FSIIDFSPNW AYAGTEIKIL  540
VMGRFLKSRE EAENFKWSIM FGEVEVPAET IADGILRCTT PSHKAGRVPF YVTCSNRVAC  600
SEVREFEYRL SHVQDITYNY INIATEDLHM RLAKLLSLSS AFPSKYDSSD VDEISQLSNK  660
ISSLLKEGNE TWDQMLKLTS LEGFSSEKLK DQLLQKALKE QLHEWLLQKV AEGGKGPSVL  720
DEGGQGVLHF AAALGYEWAL EPTIVAGVSV NFRDVNGWTA LHWAASYGRE RTVASLIHLG  780
AAPGALTDPT PKYPTGRTPA DLASANGHKG ISGFLAESAL SAHLSSLNLE KQDGDAAESS  840
GIPASLTVSD CNETPVKDAD IPIGLSLKDS LAAVCNATQA AARIHQVFRV QSFQKKQLKE  900
YGDDKFGMSH ERALSLIAVK SQKAGQYDEP VHAAIRIQNK FRGWKGRKEF LIIRQRIVKI  960
QAHVRGHQVR KNYRKIIWSV GILDKIILRW RRKGSGLRGF KSEALTEGSS MQVVSTKDDD  1020
DDFLKEGRKQ TEERSQIALA RVKSMHQHPE AREQYHRLRN VVAEIQETKA MYEWANNSEA  1080
MVEFDDLINL ETLWDGDTFL PTDS*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems, leaves, carpels, and siliques, but not in stigmas or other parts of the flower. {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:14581622}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Potri.005G075100.2

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024456349.1	0.0	calmodulin-binding transcription activator 3 isoform X2
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A2K2AD17	0.0	A0A2K2AD17_POPTR; Uncharacterized protein
STRING	POPTR_0007s05410.1	0.0	(Populus trichocarpa)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Link Out ? help Back to Top
Phytozome	Potri.005G075100.2

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]