PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus

Family

CAMTA

Protein Properties

Length: 1117aa MW: 126102 Da PI: 5.6108

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Potri.005G075100.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	177.1	2.3e-55	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenp 92 ++ ++rwl++ ei++iL n+++++++ e+++ p+sgsl+L++rk++ryfrkDG++w+kkkdgktv+E+he+LK g+v+vl+cyYah+e+n+ Potri.005G075100.1 20 VEAQNRWLRPAEIVEILSNYQRFRIAPEPAHMPPSGSLFLFDRKVLRYFRKDGHNWRKKKDGKTVKEAHERLKSGSVDVLHCYYAHGEDNE 110 6679************************************************************************************* PP CG-1 93 tfqrrcywlLeeelekivlvhylevk 118 +fqrr+yw+Leeel++ivlvhy+evk Potri.005G075100.1 111 NFQRRSYWMLEEELSHIVLVHYREVK 136 *********************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	81.374	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	2.1E-75	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	1.2E-48	21	134	IPR005559	CG-1 DNA-binding domain
Gene3D	G3DSA:2.60.40.10	9.5E-5	534	621	IPR013783	Immunoglobulin-like fold
SuperFamily	SSF81296	2.49E-15	535	621	IPR014756	Immunoglobulin E-set
Pfam	PF01833	1.4E-5	535	618	IPR002909	IPT domain
PROSITE profile	PS50297	19.041	706	839	IPR020683	Ankyrin repeat-containing domain
Gene3D	G3DSA:1.25.40.20	1.5E-17	715	831	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	1.00E-12	716	827	No hit	No description
SuperFamily	SSF48403	2.95E-16	722	829	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	4.8E-7	740	830	IPR020683	Ankyrin repeat-containing domain
SMART	SM00248	0.011	768	797	IPR002110	Ankyrin repeat
PROSITE profile	PS50088	9.778	768	800	IPR002110	Ankyrin repeat
SMART	SM00248	930	807	836	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	1.14E-7	938	992	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	2	941	963	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	8.206	944	971	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.0047	944	962	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.0039	964	986	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.597	965	989	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	2.3E-4	967	986	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0045944	Biological Process	positive regulation of transcription from RNA polymerase II promoter
GO:0005634	Cellular Component	nucleus
GO:0001077	Molecular Function	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0005515	Molecular Function	protein binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 1117 aa Download sequence Send to blast
MADSRRYPLG NQLDIQQILV EAQNRWLRPA EIVEILSNYQ RFRIAPEPAH MPPSGSLFLF 60 DRKVLRYFRK DGHNWRKKKD GKTVKEAHER LKSGSVDVLH CYYAHGEDNE NFQRRSYWML 120 EEELSHIVLV HYREVKGTRT NFNRIKEYEE PIPYSQETKD MMPNSEMDTS VSSSFRSNGY 180 QVPTGTTDST SMNSALASEY EDAESGYNNQ ASSRFNSFLE VQRPAMEKMD TGTSIPYDHM 240 LFSSGYQGKM PAVPVMEFIS PAQVDTAKDT IGTEPASEPQ KVFDLPSWED VLENCSRGIE 300 SVPFQTTLLS QVDTVGVIPK QEDILEKFLA NSFDKRQGMV GVIPKQEDIL EKFLTNSFDR 360 SQDIGSHLLD QEAWQTIEGG YSHRPKWSLD QKLHLDSDLT ARFHDQQLDS GNFINTFEPF 420 CAQENDNHIQ NDLQIQPANS DHGMTLDEKS IYSTSMKQHI LDDSRTEGLK KLDSFTRWMS 480 KELEDVDQPH LQSSSGTYWI SAESENVVDA DNPSHGHLDT YTLGPSLSQD QLFSIIDFSP 540 NWAYAGTEIK ILVMGRFLKS REEAENFKWS IMFGEVEVPA ETIADGILRC TTPSHKAGRV 600 PFYVTCSNRV ACSEVREFEY RLSHVQDITY NYINIATEDL HMRLAKLLSL SSAFPSKYDS 660 SDVDEISQLS NKISSLLKEG NETWDQMLKL TSLEGFSSEK LKDQLLQKAL KEQLHEWLLQ 720 KVAEGGKGPS VLDEGGQGVL HFAAALGYEW ALEPTIVAGV SVNFRDVNGW TALHWAASYG 780 RERTVASLIH LGAAPGALTD PTPKYPTGRT PADLASANGH KGISGFLAES ALSAHLSSLN 840 LEKQDGDAAE SSGIPASLTV SDCNETPVKD ADIPIGLSLK DSLAAVCNAT QAAARIHQVF 900 RVQSFQKKQL KEYGDDKFGM SHERALSLIA VKSQKAGQYD EPVHAAIRIQ NKFRGWKGRK 960 EFLIIRQRIV KIQAHVRGHQ VRKNYRKIIW SVGILDKIIL RWRRKGSGLR GFKSEALTEG 1020 SSMQVVSTKD DDDDFLKEGR KQTEERSQIA LARVKSMHQH PEAREQYHRL RNVVAEIQET 1080 KAMYEWANNS EAMVEFDDLI NLETLWDGDT FLPTDS*

Sequence ? help Back to Top

Protein Sequence Length: 1117 aa Download sequence Send to blast

MADSRRYPLG NQLDIQQILV EAQNRWLRPA EIVEILSNYQ RFRIAPEPAH MPPSGSLFLF  60
DRKVLRYFRK DGHNWRKKKD GKTVKEAHER LKSGSVDVLH CYYAHGEDNE NFQRRSYWML  120
EEELSHIVLV HYREVKGTRT NFNRIKEYEE PIPYSQETKD MMPNSEMDTS VSSSFRSNGY  180
QVPTGTTDST SMNSALASEY EDAESGYNNQ ASSRFNSFLE VQRPAMEKMD TGTSIPYDHM  240
LFSSGYQGKM PAVPVMEFIS PAQVDTAKDT IGTEPASEPQ KVFDLPSWED VLENCSRGIE  300
SVPFQTTLLS QVDTVGVIPK QEDILEKFLA NSFDKRQGMV GVIPKQEDIL EKFLTNSFDR  360
SQDIGSHLLD QEAWQTIEGG YSHRPKWSLD QKLHLDSDLT ARFHDQQLDS GNFINTFEPF  420
CAQENDNHIQ NDLQIQPANS DHGMTLDEKS IYSTSMKQHI LDDSRTEGLK KLDSFTRWMS  480
KELEDVDQPH LQSSSGTYWI SAESENVVDA DNPSHGHLDT YTLGPSLSQD QLFSIIDFSP  540
NWAYAGTEIK ILVMGRFLKS REEAENFKWS IMFGEVEVPA ETIADGILRC TTPSHKAGRV  600
PFYVTCSNRV ACSEVREFEY RLSHVQDITY NYINIATEDL HMRLAKLLSL SSAFPSKYDS  660
SDVDEISQLS NKISSLLKEG NETWDQMLKL TSLEGFSSEK LKDQLLQKAL KEQLHEWLLQ  720
KVAEGGKGPS VLDEGGQGVL HFAAALGYEW ALEPTIVAGV SVNFRDVNGW TALHWAASYG  780
RERTVASLIH LGAAPGALTD PTPKYPTGRT PADLASANGH KGISGFLAES ALSAHLSSLN  840
LEKQDGDAAE SSGIPASLTV SDCNETPVKD ADIPIGLSLK DSLAAVCNAT QAAARIHQVF  900
RVQSFQKKQL KEYGDDKFGM SHERALSLIA VKSQKAGQYD EPVHAAIRIQ NKFRGWKGRK  960
EFLIIRQRIV KIQAHVRGHQ VRKNYRKIIW SVGILDKIIL RWRRKGSGLR GFKSEALTEG  1020
SSMQVVSTKD DDDDFLKEGR KQTEERSQIA LARVKSMHQH PEAREQYHRL RNVVAEIQET  1080
KAMYEWANNS EAMVEFDDLI NLETLWDGDT FLPTDS*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems, leaves, carpels, and siliques, but not in stigmas or other parts of the flower. {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:14581622}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Potri.005G075100.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024456348.1	0.0	calmodulin-binding transcription activator 3 isoform X1
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A2K2AD13	0.0	A0A2K2AD13_POPTR; Uncharacterized protein
STRING	POPTR_0007s05410.1	0.0	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8284	27	35
Representative plant	OGRP562	15	65

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Link Out ? help Back to Top
Phytozome	Potri.005G075100.1

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]