PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus

Family

HSF

Protein Properties

Length: 508aa MW: 55694.9 Da PI: 4.6061

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Potri.003G095000.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	113	2e-35	37	128	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkke 92 Fl+k+y++++d++++ ++sws+++nsfvv+++ efa+++LpkyFkh+nf+SFvRQLn+YgF+kv+ ++ weF+++ F +g+k+ Potri.003G095000.1 37 FLSKTYDMVDDPATDAVVSWSSTNNSFVVWNPPEFARDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLRGQKH 118 9**************************************************************999.........********** PP XXXXXXXXXX CS HSF_DNA-bind 93 llekikrkks 102 ll+ i r+k Potri.003G095000.1 119 LLRIISRRKP 128 *****986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	4.1E-40	27	120	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	1.9E-35	33	126	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	3.9E-62	33	126	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	2.2E-31	37	126	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	3.6E-20	37	60	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	3.6E-20	75	87	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	76	100	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	3.6E-20	88	100	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 508 aa Download sequence Send to blast
MDGTINSASG GDSSISGGGA QAASVPMASQ SNAPPPFLSK TYDMVDDPAT DAVVSWSSTN 60 NSFVVWNPPE FARDLLPKYF KHNNFSSFVR QLNTYGFRKV DPDRWEFANE GFLRGQKHLL 120 RIISRRKPAH GHANQQPQQP HGQNSSVAAC VEVGKFGLEE EVERLKRDKN VLMQELVRLR 180 QQQQSTDSQL QTMVQRLQGM EQRQQQMMSF LAKAMNSPGF LAQFVQQQND NNRRITEANK 240 KRRLKQEDVP ENEGSGSHDG QIVKYQPLMN EAAQAMLRQI MKMDASSKLE SYDNNLGAKD 300 SGSSSSHTSG VTLQEVLPTS GQSAHIPAAF GISRQGPSAP ISEIQSSLQI ASSEKVTASQ 360 FPDISMPVGA QGATSIPIPQ ADVIMPHVSQ MLEMVPENVA DIPCEDYMEP ETCNDGFIDL 420 ASLGINGIPI DIDNISPDPD IDALLDNSSF WDDLLVQSPE HEDIESSSVE GKANGNDVQP 480 NANGWDKAQH VDQLTEQMEL LTSDKKL*

Sequence ? help Back to Top

Protein Sequence Length: 508 aa Download sequence Send to blast

MDGTINSASG GDSSISGGGA QAASVPMASQ SNAPPPFLSK TYDMVDDPAT DAVVSWSSTN  60
NSFVVWNPPE FARDLLPKYF KHNNFSSFVR QLNTYGFRKV DPDRWEFANE GFLRGQKHLL  120
RIISRRKPAH GHANQQPQQP HGQNSSVAAC VEVGKFGLEE EVERLKRDKN VLMQELVRLR  180
QQQQSTDSQL QTMVQRLQGM EQRQQQMMSF LAKAMNSPGF LAQFVQQQND NNRRITEANK  240
KRRLKQEDVP ENEGSGSHDG QIVKYQPLMN EAAQAMLRQI MKMDASSKLE SYDNNLGAKD  300
SGSSSSHTSG VTLQEVLPTS GQSAHIPAAF GISRQGPSAP ISEIQSSLQI ASSEKVTASQ  360
FPDISMPVGA QGATSIPIPQ ADVIMPHVSQ MLEMVPENVA DIPCEDYMEP ETCNDGFIDL  420
ASLGINGIPI DIDNISPDPD IDALLDNSSF WDDLLVQSPE HEDIESSSVE GKANGNDVQP  480
NANGWDKAQH VDQLTEQMEL LTSDKKL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	1e-27	13	126	5	129	Heat shock factor protein 1
5d5v_B	1e-27	13	126	5	129	Heat shock factor protein 1
5d5v_D	1e-27	13	126	5	129	Heat shock factor protein 1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	238	245	NKKRRLKQ
2	239	244	KKRRLK

Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Potri.003G095000.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JF905565	0.0	JF905565.1 Populus simonii clone JL heat shock transcription factor (HsfA1d) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002303429.2	0.0	heat shock factor protein HSF8
Swissprot	Q40152	1e-172	HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBL	B9GZI0	0.0	B9GZI0_POPTR; Uncharacterized protein
STRING	POPTR_0003s09370.1	0.0	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1843	31	69
Representative plant	OGRP96	17	233

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G32330.1	1e-127	heat shock transcription factor A1D

Link Out ? help Back to Top
Phytozome	Potri.003G095000.1
Entrez Gene	7491874

Publications ? help Back to Top
Zhu B, et al. Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max). J. Plant Res., 2006. 119(3): p. 247-56 [PMID:16570125] Cai SY, et al. HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants. J. Pineal Res., 2017. [PMID:28095626] Zhou J, et al. Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1. Plant Physiol., 2018. 176(3): p. 2456-2471 [PMID:29339397]