PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Phaseolus

Family

C2H2

Protein Properties

Length: 549aa MW: 60236 Da PI: 8.3268

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Phvul.L007800.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.1	1.6e-05	85	107	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Phvul.L007800.1 85 FVCEICNKGFQRDQNLQLHRRGH 107 89*******************88 PP
2	zf-C2H2	16.1	3.2e-05	161	183	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k++ +s+ k H++t+ Phvul.L007800.1 161 WKCDKCSKRYAVQSDWKAHQKTC 183 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	3.28E-8	84	107	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.8E-5	84	107	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.949	85	107	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.017	85	107	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	87	107	IPR007087	Zinc finger, C2H2
SMART	SM00355	75	126	156	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	9.2E-6	149	182	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.28E-8	156	182	No hit	No description
SMART	SM00355	89	161	181	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 549 aa Download sequence Send to blast
MSNISGDEGS LSSANTVEEV HQESEQQQPQ NRHGSSSGAC NTNSSTSQQQ QQQSTKKKRN 60 LPGTPDPNAE VIALSPTTLM ATNRFVCEIC NKGFQRDQNL QLHRRGHNLP WKLRQRPSNE 120 VKKRVYVCPE PSCVHHNPAR ALGDLTGIKK HYSRKHGEKK WKCDKCSKRY AVQSDWKAHQ 180 KTCGTREYKC DCGTIFARRD SFITHRAFCD ALTEENNRVN PSLTTGASMT PSLQNELQDL 240 MATMPLSTSP NNAVPEFNSN YDPSKSPLKT LSQQHLVPMP FKSMSMRGCM SSTTSGTLFG 300 GPKNVSLPSS STLQLSTNNS HTFNYFQDSK NAAASAHMSA TALLQKAAQM GAAATNNSIN 360 SPTMMQKSFV SGMTGPDPNH NPSSYDPFHP PHSDDQSHMA GISGAGAFTN QFFYKGQQEI 420 SVILDSNTSD MGIFGAMFMG NEHNQGVMKN VEQEVGANGS GLIHRRDVSE GNPMGDSRFG 480 GGDMTRVHDF LGVGGATSRA GSLHETQKQQ QQSLELEALT HQRLQMINHF HHHLPHGDSA 540 MEKSIWDI*

Sequence ? help Back to Top

Protein Sequence Length: 549 aa Download sequence Send to blast

MSNISGDEGS LSSANTVEEV HQESEQQQPQ NRHGSSSGAC NTNSSTSQQQ QQQSTKKKRN  60
LPGTPDPNAE VIALSPTTLM ATNRFVCEIC NKGFQRDQNL QLHRRGHNLP WKLRQRPSNE  120
VKKRVYVCPE PSCVHHNPAR ALGDLTGIKK HYSRKHGEKK WKCDKCSKRY AVQSDWKAHQ  180
KTCGTREYKC DCGTIFARRD SFITHRAFCD ALTEENNRVN PSLTTGASMT PSLQNELQDL  240
MATMPLSTSP NNAVPEFNSN YDPSKSPLKT LSQQHLVPMP FKSMSMRGCM SSTTSGTLFG  300
GPKNVSLPSS STLQLSTNNS HTFNYFQDSK NAAASAHMSA TALLQKAAQM GAAATNNSIN  360
SPTMMQKSFV SGMTGPDPNH NPSSYDPFHP PHSDDQSHMA GISGAGAFTN QFFYKGQQEI  420
SVILDSNTSD MGIFGAMFMG NEHNQGVMKN VEQEVGANGS GLIHRRDVSE GNPMGDSRFG  480
GGDMTRVHDF LGVGGATSRA GSLHETQKQQ QQSLELEALT HQRLQMINHF HHHLPHGDSA  540
MEKSIWDI*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	1e-33	157	220	3	66	Zinc finger protein JACKDAW
5b3h_F	1e-33	157	220	3	66	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Phvul.L007800.1

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AP015041	0.0	AP015041.1 Vigna angularis var. angularis DNA, chromosome 8, almost complete sequence, cultivar: Shumari.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007163889.1	0.0	hypothetical protein PHAVU_L007800g
Swissprot	Q9SCQ6	1e-112	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	V7D2F3	0.0	V7D2F3_PHAVU; Uncharacterized protein
STRING	XP_007163889.1	0.0	(Phaseolus vulgaris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2192	30	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-106	indeterminate(ID)-domain 2

Link Out ? help Back to Top
Phytozome	Phvul.L007800.1
Entrez Gene	18642726

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]