PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Phaseolus

Family

MYB

Protein Properties

Length: 328aa MW: 36685.8 Da PI: 5.2191

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Phvul.011G059800.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	43.8	6.1e-14	20	67	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g W++eEd++l ++ G g+W+ +ar g+ R++k+c++rw +yl Phvul.011G059800.1 20 KGLWSPEEDDKLMNYMLNSGQGCWSDVARNAGLQRCGKSCRLRWINYL 67 678*******************************************97 PP
2	Myb_DNA-binding	53	8.1e-17	73	116	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 rg+++++E+el+v+++ +lG++ W+ Ia++++ gRt++++k++w++ Phvul.011G059800.1 73 RGAFSPQEEELIVHLHSLLGNR-WSQIAARLP-GRTDNEIKNFWNS 116 89******************.*****.*********97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	14.14	15	67	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	1.5E-22	17	70	IPR009057	Homeodomain-like
SuperFamily	SSF46689	1.64E-27	18	114	IPR009057	Homeodomain-like
SMART	SM00717	2.4E-9	19	69	IPR001005	SANT/Myb domain
Pfam	PF00249	1.2E-12	20	67	IPR001005	SANT/Myb domain
CDD	cd00167	3.53E-8	23	67	No hit	No description
PROSITE profile	PS51294	25.754	68	122	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	9.0E-26	71	123	IPR009057	Homeodomain-like
SMART	SM00717	8.4E-16	72	120	IPR001005	SANT/Myb domain
Pfam	PF00249	2.6E-15	73	116	IPR001005	SANT/Myb domain
CDD	cd00167	1.51E-11	75	115	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009751	Biological Process	response to salicylic acid
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0050832	Biological Process	defense response to fungus
GO:1901348	Biological Process	positive regulation of secondary cell wall biogenesis
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 328 aa Download sequence Send to blast
MRKPEVSGKN NSNINYKLRK GLWSPEEDDK LMNYMLNSGQ GCWSDVARNA GLQRCGKSCR 60 LRWINYLRPD LKRGAFSPQE EELIVHLHSL LGNRWSQIAA RLPGRTDNEI KNFWNSTIKK 120 RLKNLSSNTS PNGSESSYDP NKDLNMAGFT TSNTHQDQLA DFMPMLNSSS PSPSMHATVL 180 NSIIDRLPLL DHGQNMPVSG GFFNGTEPYF SSQSGVDHKG FYLENGGVFG SVNIGAEGDM 240 YVPPLESVST TSDHNLKVES TCNTDTNNSY FDDINSVILN NCSNKRTENR AGVENLFQEE 300 LTMGEWDLEE LMKDVSSFPF LDFSNIQ*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h8a_C	3e-27	14	122	21	128	MYB TRANSFORMING PROTEIN
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as molecular switch in the NAC012/SND1-mediated transcriptional network regulating secondary wall biosynthesis. Is directly activated by NAC012/SND1 and its close homologs, including NAC043/NST1, NAC066/NST2, NAC101/VND6 and NAC030/VND7. Is required for functional expression of a number of secondary wall-associated transcription factors and secondary wall biosynthetic genes involved in cellulose, xylan and lignin synthesis. Functions redundantly with MYB46 in the transcriptional regulatory cascade leading to secondary wall formation in fibers and vessels (PubMed:19808805). Transcription activator that binds to the DNA consensus sequence 5'-ACC[AT]A[AC][TC]-3', designated as the secondary wall MYB-responsive element (SMRE). Regulates directly numerous transcription factors and a number of genes involved in secondary wall biosynthesis that contain SMRE elements in their promoters (PubMed:22197883). {ECO:0000269\|PubMed:19808805, ECO:0000269\|PubMed:22197883}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00336	DAP	Transfer from AT3G08500	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Phvul.011G059800.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AP015039	0.0	AP015039.1 Vigna angularis var. angularis DNA, chromosome 6, almost complete sequence, cultivar: Shumari.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007132019.1	0.0	hypothetical protein PHAVU_011G059800g
Swissprot	Q9C6U1	3e-75	MYB83_ARATH; Transcription factor MYB83
TrEMBL	V7AGN0	0.0	V7AGN0_PHAVU; Uncharacterized protein
STRING	XP_007132019.1	0.0	(Phaseolus vulgaris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF774	34	128

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G12870.1	1e-74	myb domain protein 46

Link Out ? help Back to Top
Phytozome	Phvul.011G059800.1
Entrez Gene	18615305

Publications ? help Back to Top
Vargas L, et al. Improving total saccharification yield of Arabidopsis plants by vessel-specific complementation of caffeoyl shikimate esterase (cse) mutants. Biotechnol Biofuels, 2016. 9: p. 139 [PMID:27390589] Piya S,Kihm C,Rice JH,Baum TJ,Hewezi T Cooperative Regulatory Functions of miR858 and MYB83 during Cyst Nematode Parasitism. Plant Physiol., 2017. 174(3): p. 1897-1912 [PMID:28512179]