PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Phvul.009G182500.2
Common NamePHAVU_009G182500g
Organism
Phaseolus vulgaris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Phaseolus
Family E2F/DP
Protein Properties Length: 349aa    MW: 39134.7 Da    PI: 8.7117
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Phvul.009G182500.2genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP757.6e-241277171
             E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                        rk+ksL+ll+++fl+l++++  + + l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  Phvul.009G182500.2 12 RKQKSLGLLCTNFLRLYNREGVRLIGLDDAASRL---GV--ERRRIYDIVNVLESVGVLARKAKNQYTWKG 77
                        79*****************999************...**..****************************98 PP
2E2F_TDP76.42.8e-24147226171
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                         r+eksL lltq+f+kl+ +s+ ++++l+e+ak L+ +     +++k+RR+YDi+NVL+++nliek     ++k+++rw g
  Phvul.009G182500.2 147 RREKSLALLTQNFVKLFICSSIEMISLDEAAKLLLGNantsIMRTKVRRLYDIANVLSSMNLIEKthttnTRKPAFRWLG 226
                         689*******************************999999999*************************999*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.4E-26879IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467855.63E-161175IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013727.6E-271277IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.2E-201377IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.5E-23143226IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.3E-29147226IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.0E-19149226IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467858.71E-13149227IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 349 aa     Download sequence    Send to blast
MSSSSTHHTY SRKQKSLGLL CTNFLRLYNR EGVRLIGLDD AASRLGVERR RIYDIVNVLE  60
SVGVLARKAK NQYTWKGFSA IPEALQELKE DGLKENPGSF DDSNDSAKVS DDEDEEETSP  120
NVNTESQNDK EITDSAALAL SSKNENRREK SLALLTQNFV KLFICSSIEM ISLDEAAKLL  180
LGNANTSIMR TKVRRLYDIA NVLSSMNLIE KTHTTNTRKP AFRWLGWRGK AWSESVDFAH  240
NSSVNELGKR KFGTDITNAS FKRSKTDLLL DGQTCKMQSQ RENVSYTQPE KSYLEKDAKQ  300
TSKGYQFGPF APAYVPKVGT SESNSGNQVH DWDSLAQVHR PQYQNQGI*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-39112183228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPhvul.009G182500.2
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAP0150351e-165AP015035.1 Vigna angularis var. angularis DNA, chromosome 2, almost complete sequence, cultivar: Shumari.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007138127.10.0hypothetical protein PHAVU_009G182500g
SwissprotQ8LSZ41e-112E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLV7B0Y60.0V7B0Y6_PHAVU; Uncharacterized protein
STRINGXP_007138128.10.0(Phaseolus vulgaris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.11e-116DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]