PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Phvul.005G011500.1
Common NamePHAVU_005G011500g
Organism
Phaseolus vulgaris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Phaseolus
Family C2H2
Protein Properties Length: 431aa    MW: 49715.9 Da    PI: 7.5275
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Phvul.005G011500.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2120.00066188210123
                         EEETTTTEEESSHHHHHHHHHHT CS
             zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                         y C+ C    +rk++L+rH+r++
  Phvul.005G011500.1 188 YFCEFCLNFMKRKEQLQRHMRKC 210
                         78*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541604.76E-2438155IPR016197Chromo domain-like
Gene3DG3DSA:2.30.30.2703.5E-3740114No hitNo description
PfamPF117173.3E-2044102IPR025995RNA binding activity-knot of a chromodomain
CDDcd000247.37E-758103No hitNo description
SMARTSM002983.0E-758117IPR000953Chromo/chromo shadow domain
Gene3DG3DSA:2.30.30.2703.5E-37149199No hitNo description
PROSITE profilePS5172675.605154425IPR002717Histone acetyltransferase domain, MYST-type
SuperFamilySSF557295.22E-111155426IPR016181Acyl-CoA N-acyltransferase
Gene3DG3DSA:3.40.630.304.0E-73213356IPR016181Acyl-CoA N-acyltransferase
PfamPF018532.9E-84215392IPR002717Histone acetyltransferase domain, MYST-type
CDDcd043010.00206266324No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006281Biological ProcessDNA repair
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010224Biological Processresponse to UV-B
GO:0016573Biological Processhistone acetylation
GO:2000028Biological Processregulation of photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0043995Molecular Functionhistone acetyltransferase activity (H4-K5 specific)
Sequence ? help Back to Top
Protein Sequence    Length: 431 aa     Download sequence    Send to blast
MGSLETPTGS GPSAGNGKST SVDAAEAPPE PDMSKRRRSS VLPLEVGTRV MCRWRDSKYH  60
PVKVIERRKV SNAIPGDYEY YVHYTEFNRR LDEWVKLDQL DLDSVEAVVD EKVEEKGASG  120
LKMTRHQKRK IDETHVEGHE ELDAASLREH EEFTKVKNIA TIELGRYEIE TWYFSPFPPE  180
YNDCLRLYFC EFCLNFMKRK EQLQRHMRKC DLKHPPGDEI YRSGTLSMFE VDGKKNKVYG  240
QNLCYLAKLF LDHKTLYYDV DLFLFYVLCE CDDRGCHMVG YFSKEKHSEE SYNLACILTL  300
PPYQRKGYGK FLIAFSYELS KKEGKVGTPE RPLSDLGLLS YRGYWTRVLL DILKKHKGNI  360
SIKELSDMTA IKAEDILTTL QSLELIQYRK GQHVICADPK VLDRHLKAAG RGGLDVDVSK  420
LIWTPYKEQS *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4dnc_A1e-1181504291282Histone acetyltransferase KAT8
4dnc_B1e-1181504291282Histone acetyltransferase KAT8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtHistone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPhvul.005G011500.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT1420750.0BT142075.1 Lotus japonicus clone JCVI-FLLj-11A9 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007148756.10.0hypothetical protein PHAVU_005G011500g
SwissprotQ9FLF70.0MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBLV7BUM20.0V7BUM2_PHAVU; Histone acetyltransferase
STRINGXP_007148756.10.0(Phaseolus vulgaris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF70661011
Publications ? help Back to Top
  1. Latrasse D, et al.
    The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 121
    [PMID:19040736]
  2. Campi M,D'Andrea L,Emiliani J,Casati P
    Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
    Plant Physiol., 2012. 158(2): p. 981-95
    [PMID:22170978]
  3. Bari A,Orazova S,Ivashchenko A
    miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
    Biomed Res Int, 2013. 2013: p. 307145
    [PMID:23936788]
  4. Xu Y, et al.
    Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
    Nucleic Acids Res., 2014. 42(17): p. 10960-74
    [PMID:25183522]
  5. Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
    3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
    J Mol Model, 2016. 22(11): p. 256
    [PMID:27709438]
  6. Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
    HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1179
    [PMID:28740501]