PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Phvul.002G141500.1

Common Name

PHAVU_002G141500g

Organism

Phaseolus vulgaris

Taxonomic ID

3885

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Phaseolus

Family

bHLH

Protein Properties

Length: 729aa MW: 79679.6 Da PI: 6.8398

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Phvul.002G141500.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	38.1	2.8e-12	548	593	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h e+Er+RR+++N++f Lr ++P+ K++Ka+ L A+ YI +L Phvul.002G141500.1 548 NHVEAERQRREKLNQRFYALRAVVPNV-----SKMDKASLLGDAISYITEL 593 799*********************6.....5*************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	4.3E-58	118	299	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	17.193	544	593	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.83E-18	545	615	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	8.22E-15	547	598	No hit	No description
Pfam	PF00010	8.8E-10	548	593	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	8.2E-19	548	613	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.3E-16	550	599	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 729 aa Download sequence Send to blast
MVTPGRVLTK NSPWGIWVSR KARTCSLSLA LRVYPLFSFF FSPVLPSKPN QFQFPKPQSP 60 ITTHQSLTST TSVSEWMNLW TDDNSSVMEA FMSSPDLSSI WPPPAPPQSA AVFNQDTLQH 120 RLQALIEGAR ESWTYAIFWQ HSYDYSGSAL LGWGDGYYKG DDDKAKAKAK AKATSAAEQD 180 HRKKVLRELN SLISGSSAAS SDDVDEEVTD TEWFFLVSMT QSFVNGAGLP GQAFFNSNPV 240 WVIGGDRLST SPCERARQGQ VFGLQTLVCI PSANGVVELG STELIYQNPD LMNKVKVLFN 300 FSNNNFDMGS SWPATSADQG ENDPSTLWLN DPEVRDSINT AAATPSVSVS VPPHNSTHGI 360 SKTMQLESSI QTPGSSTLTE TPSSIHAVPQ NQSVFSRELN FSEYGFDPKS GNTHNQHSLK 420 PESCEIFSFS DSKRTSYGGG GGGVNGNSNS NSNFFSGQSP FVAVADENNN NNNGKRRSPN 480 SRGSNDDGML SFTSRAILPA TNLKSAGGGD SDHSDLEASV VKDPVVEPEK RPRKRGRKPA 540 NGREEPLNHV EAERQRREKL NQRFYALRAV VPNVSKMDKA SLLGDAISYI TELKSKLQNL 600 ESDKDGLQKQ LEGVKKELEK SSDNVSSNHT KHGGNSNIKS SNQALIDLDI DVKIIGWDAM 660 IRIQCSKKNH PAARLMAALM ELDLDVHHAS VSVVNDLMIQ QATVKMGSRF YTQEQLRSAL 720 SAKVGDVR*

Sequence ? help Back to Top

Protein Sequence Length: 729 aa Download sequence Send to blast

MVTPGRVLTK NSPWGIWVSR KARTCSLSLA LRVYPLFSFF FSPVLPSKPN QFQFPKPQSP  60
ITTHQSLTST TSVSEWMNLW TDDNSSVMEA FMSSPDLSSI WPPPAPPQSA AVFNQDTLQH  120
RLQALIEGAR ESWTYAIFWQ HSYDYSGSAL LGWGDGYYKG DDDKAKAKAK AKATSAAEQD  180
HRKKVLRELN SLISGSSAAS SDDVDEEVTD TEWFFLVSMT QSFVNGAGLP GQAFFNSNPV  240
WVIGGDRLST SPCERARQGQ VFGLQTLVCI PSANGVVELG STELIYQNPD LMNKVKVLFN  300
FSNNNFDMGS SWPATSADQG ENDPSTLWLN DPEVRDSINT AAATPSVSVS VPPHNSTHGI  360
SKTMQLESSI QTPGSSTLTE TPSSIHAVPQ NQSVFSRELN FSEYGFDPKS GNTHNQHSLK  420
PESCEIFSFS DSKRTSYGGG GGGVNGNSNS NSNFFSGQSP FVAVADENNN NNNGKRRSPN  480
SRGSNDDGML SFTSRAILPA TNLKSAGGGD SDHSDLEASV VKDPVVEPEK RPRKRGRKPA  540
NGREEPLNHV EAERQRREKL NQRFYALRAV VPNVSKMDKA SLLGDAISYI TELKSKLQNL  600
ESDKDGLQKQ LEGVKKELEK SSDNVSSNHT KHGGNSNIKS SNQALIDLDI DVKIIGWDAM  660
IRIQCSKKNH PAARLMAALM ELDLDVHHAS VSVVNDLMIQ QATVKMGSRF YTQEQLRSAL  720
SAKVGDVR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rru_A	1e-76	79	295	7	227	Transcription factor MYC3
4ywc_A	1e-76	79	295	7	227	Transcription factor MYC3
4ywc_B	1e-76	79	295	7	227	Transcription factor MYC3
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	529	537	KRPRKRGRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that binds to the G-box motif (5'-AACGTG-3') found in the promoter of the jasmonate-induced gene LAPA1 (PubMed:15231736). Acts as negative regulator of blue light-mediated photomorphogenesis and positively regulates root growth (PubMed:24483714). Promotes growth in response to the phytohormones abscisic acid (ABA) and jasmonate (JA) (PubMed:24483714). Binds to the G-box motif (5'-CACGTG-3') of the RBCS-3A gene promoter (PubMed:24483714). Acts downstream of the jasmonate (JA) receptor to orchestrate JA-mediated activation of plant responses (PubMed:28733419). Positively regulates both wound-responsive and pathogen-responsive genes through MYC2-targeted transcription factors (MTFs) involved in early response to JA (PubMed:28733419). With JA2L forms a transcription module that regulates wounding-responsive genes (PubMed:28733419). With ERF.C3 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). Plays a critical role in orchestrating JA-mediated defense gene expression during Botrytis cinerea infection (PubMed:28733419). Regulates negatively defense responses to root-knot nematodes, potentially by mediating crosstalk among the hormones strigolactones, abscisic acid (ABA) and jasmonate (JA) (PubMed:30576511). Regulates the termination of JA-mediated defense responses by specifically binding the G-box (5'-CACATG-3') motifs in the promoters of MTB1, MTB2 and MTB3, which are transcription factors that negatively regulates JA signaling (PubMed:30610166). May be involved in JA-induced chilling tolerance, possibly by ameliorating the antioxidant enzyme system of fruit and increasing proline and lycopene levels (PubMed:29528226). {ECO:0000269\|PubMed:15231736, ECO:0000269\|PubMed:24483714, ECO:0000269\|PubMed:28733419, ECO:0000269\|PubMed:29528226, ECO:0000269\|PubMed:30576511, ECO:0000269\|PubMed:30610166}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Phvul.002G141500.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by methyl jasmonate (PubMed:15231736, PubMed:28733419). Induced by wounding (PubMed:15231736). Induced by infection with the fungal pathogen Botrytis cinerea (PubMed:28733419). Induced in fruit by storage in cold (PubMed:29528226). Induced by hydrogen peroxide and infection with root-knot nematodes (PubMed:30576511). {ECO:0000269\|PubMed:15231736, ECO:0000269\|PubMed:28733419, ECO:0000269\|PubMed:29528226, ECO:0000269\|PubMed:30576511}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	PVU18349	0.0	U18349.1 Phaseolus vulgaris phaseolin G-box binding protein PG2 (PG2) mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007158304.1	0.0	hypothetical protein PHAVU_002G141500g
Swissprot	A0A3Q7HRZ6	0.0	MYC2_SOLLC; Transcription factor MYC2
TrEMBL	V7CLS1	0.0	V7CLS1_PHAVU; Uncharacterized protein
STRING	XP_007158304.1	0.0	(Phaseolus vulgaris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2938	33	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G32640.1	0.0	bHLH family protein

Link Out ? help Back to Top
Phytozome	Phvul.002G141500.1
Entrez Gene	18637930

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Gupta N,Prasad VB,Chattopadhyay S LeMYC2 acts as a negative regulator of blue light mediated photomorphogenic growth, and promotes the growth of adult tomato plants. BMC Plant Biol., 2014. 14: p. 38 [PMID:24483714] Sun H,Fan HJ,Ling HQ Genome-wide identification and characterization of the bHLH gene family in tomato. BMC Genomics, 2015. 16: p. 9 [PMID:25612924] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419] Min D, et al. SlMYC2 Involved in Methyl Jasmonate-Induced Tomato Fruit Chilling Tolerance. J. Agric. Food Chem., 2018. 66(12): p. 3110-3117 [PMID:29528226] Xu X, et al. Strigolactones positively regulate defense against root-knot nematodes in tomato. J. Exp. Bot., 2019. 70(4): p. 1325-1337 [PMID:30576511] Liu Y, et al. MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop. Plant Cell, 2019. 31(1): p. 106-127 [PMID:30610166]