PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Peinf101Scf00364g01018.1

Organism

Petunia inflata

Taxonomic ID

212142

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Petunioideae; Petunia; Petunia integrifolia

Family

bHLH

Protein Properties

Length: 320aa MW: 36218.8 Da PI: 5.4535

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Peinf101Scf00364g01018.1	genome	SGN	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	28.7	2.4e-09	181	210	1	30
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC CS HLH 1 rrrahnerErrRRdriNsafeeLrellPka 30 +r++h ++Er+RR+++N+ + Lr+l+P + Peinf101Scf00364g01018.1 181 QRMTHIAVERNRRKQMNEHLRVLRSLMPGS 210 79**************************85 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:4.10.280.10	4.3E-8	179	214	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	5.62E-7	179	214	No hit	No description
PROSITE profile	PS50888	10.785	180	233	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.6E-8	180	215	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.1E-6	181	210	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd04873	0.00191	246	310	No hit	No description
SuperFamily	SSF55021	4.12E-5	246	310	No hit	No description
PROSITE profile	PS51671	8.841	246	320	IPR002912	ACT domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008152	Biological Process	metabolic process
GO:0016597	Molecular Function	amino acid binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 320 aa Download sequence Send to blast
MEKEENCQAN SLPTTFQMVG ESTSGGANNN QMVDYMLNSH HALQQQQHPN SLGFCPSTSF 60 HDKLSFADVM QFADFGPKLA LNQTKVSDEE TGIIDPVYFL KFPVLNEKLQ DDDDQGLMVQ 120 QNEEKFKVVE EVGKEKAINT LDVQVPYVGE NLERSPQGNE GNKSNKRKRP RIKSSEEVES 180 QRMTHIAVER NRRKQMNEHL RVLRSLMPGS YVQRNDYIEA GIREETAESK SCLADVEVKL 240 LGFDAMIKIL SRRRPGQLIK TIAALEDLQL NILHTNITTI EQTVLYSFNV KISGETRCTA 300 DDIANSIQQI FSFIHANSPI

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	181	192	RMTHIAVERNRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956). {ECO:0000269\|PubMed:17088607, ECO:0000269\|PubMed:17183265, ECO:0000269\|PubMed:17183267, ECO:0000269\|PubMed:24571519, ECO:0000269\|PubMed:24654956}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Inhibited by low relative humidity (LRH) via epigenetic CG methylation, thus leading to a reduced stomatal index. {ECO:0000269\|PubMed:22442411}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975444	8e-56	HG975444.1 Solanum pennellii chromosome ch05, complete genome.
GenBank	HG975517	8e-56	HG975517.1 Solanum lycopersicum chromosome ch05, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028095058.1	1e-110	transcription factor FAMA isoform X2
Swissprot	Q56YJ8	5e-53	FAMA_ARATH; Transcription factor FAMA
TrEMBL	A0A2P5R3N8	1e-120	A0A2P5R3N8_GOSBA; Uncharacterized protein
STRING	XP_010532793.1	1e-102	(Tarenaya hassleriana)
STRING	POPTR_0017s08160.1	1e-102	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA4657	23	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G24140.1	3e-55	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Matos JL, et al. Irreversible fate commitment in the Arabidopsis stomatal lineage requires a FAMA and RETINOBLASTOMA-RELATED module. Elife, 2015. [PMID:25303364] Chen L, et al. NRPB3, the third largest subunit of RNA polymerase II, is essential for stomatal patterning and differentiation in Arabidopsis. Development, 2016. 143(9): p. 1600-11 [PMID:26989174] Lee JH,Jung JH,Park CM Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce Stomatal Development in Arabidopsis. Plant Cell, 2017. 29(11): p. 2817-2830 [PMID:29070509] Han X, et al. Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons. Plant Physiol., 2018. 176(4): p. 2871-2885 [PMID:29496884] Li X,Yang R,Chen H The Arabidopsis thaliana Mediator subunit MED8 regulates plant immunity to Botrytis Cinerea through interacting with the basic helix-loop-helix (bHLH) transcription factor FAMA. PLoS ONE, 2018. 13(3): p. e0193458 [PMID:29513733]