PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pbr028900.1

Organism

Pyrus bretschneideri

Taxonomic ID

225117

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

CAMTA

Protein Properties

Length: 1115aa MW: 124972 Da PI: 6.2455

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr028900.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	179.6	3.8e-56	25	141	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqrrcy 99 l+ k+rwl++ ei++iL+n++k+++++ ++++p+ gsl+L++rk++ryfrkDG++w+kkkdgktv+E+he+LK g+v+vl+cyYah+een++fqrr+y Pbr028900.1 25 LEAKHRWLRPAEICEILQNYQKFQIASVPANKPPGGSLFLFDRKVLRYFRKDGHNWRKKKDGKTVKEAHERLKAGSVDVLHCYYAHGEENENFQRRSY 122 6679******************************************************************************************** PP CG-1 100 wlLeeelekivlvhylevk 118 w+Lee+l++ivlvhy+evk Pbr028900.1 123 WMLEEALQHIVLVHYREVK 141 **************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	82.292	20	146	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	1.8E-78	23	141	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	1.2E-49	26	139	IPR005559	CG-1 DNA-binding domain
Gene3D	G3DSA:2.60.40.10	1.6E-5	526	612	IPR013783	Immunoglobulin-like fold
Pfam	PF01833	3.7E-7	527	611	IPR002909	IPT domain
SuperFamily	SSF81296	9.27E-18	527	612	IPR014756	Immunoglobulin E-set
SuperFamily	SSF48403	6.73E-16	705	821	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	1.35E-12	707	819	No hit	No description
PROSITE profile	PS50297	16.865	710	821	IPR020683	Ankyrin repeat-containing domain
Gene3D	G3DSA:1.25.40.20	3.2E-16	710	822	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50088	9.618	760	792	IPR002110	Ankyrin repeat
SMART	SM00248	0.011	760	789	IPR002110	Ankyrin repeat
Pfam	PF13637	7.1E-5	762	819	No hit	No description
SMART	SM00248	660	799	828	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	2.44E-7	930	985	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	14	934	956	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	7.364	936	964	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.051	937	955	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.012	957	979	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.267	958	982	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	5.9E-4	960	979	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 1115 aa Download sequence Send to blast
MSIIMTHSRL VVLWFAHDNI AQILLEAKHR WLRPAEICEI LQNYQKFQIA SVPANKPPGG 60 SLFLFDRKVL RYFRKDGHNW RKKKDGKTVK EAHERLKAGS VDVLHCYYAH GEENENFQRR 120 SYWMLEEALQ HIVLVHYREV KGNRTNYNHI KGTEEGVPYS HETEEVALNS EMDNSVSSSF 180 NPSSFQMRSQ ATDATSLSSA QASEFEDAES VYNHQASSQL QPFLELLQPK AEKTNAGVST 240 AFYPMSFSDE YQEKLSAIPG VNFSSHTQAY RKEDVKDAGV TYDPRRNLNS TLCDGALGNI 300 TTGFQSLPFQ PSISATHSDS TGIISKQENE TFGHLFTNNF GKKQMYEDRP RVQQSWQQTL 360 EANSSGSSSG PVDQNLHSNT AYDVSTRFHE GVDASNLLNS LVCHVDSDKT NDYSMPNDLQ 420 IQPSNPEQEC HLKSISKRNE TIEGSNNHAF ATRPLLDEGL KKLDSFNRWM SKELGDVDET 480 QTQSNSETYW DTVESENGVD ESSVPLHVRL DSYMLGPSLS QDQLFSIIDF SPNWAYENSE 540 IKVLITGRFL KSQEAKSCKW SCMFGEVEVP AEVIADGVLR CYTPIHKAGR IPFYVTCSNR 600 LACSEIREFE YRVGQIPDYD AKDDYSGCMN EILNMRFGKL LSLSSSSPTF DPTSIAENSE 660 LISKIDLLLK NDNGEWDRML QLTSDEDFSL ERVEDQLLQQ LLKEKLHAWL LQKLAAGGKG 720 PSVLDEGGQG VLHFGAALGY DWVLLPTITA GVSVNFRDVN GWTALHWAAF HGRERTVASL 780 ISLGAAPGLL TDPRTKYPAG RTPADLASAR GHKGIAGYLA ESALSDHLSF LNLDVKEGNN 840 AEISGAKAVE TASERIATPI RNGDLTGGLS LRDSLTAVCN ATQAAARIHQ VLRVKSFQRK 900 QLKEYGSDNF GISDEDALSL IAVKSHKPGK RDEHVDAAAI RIQNKFRSWK GRKDYLIIRQ 960 RIVKLQAHVR GHQVRKNYRK IVWSVGIVEK IILRWRRKGS GLRGFKPEAL AEPPSMQASS 1020 SKDDDYDVLK EGRKQTEQRL QKALARVKSM VRYPEARDQY SRLLNVVTEI QETKVVYDSI 1080 MNSSDGRADM DDDLVDFAAL LDEDDVCMPT AAPE*

Sequence ? help Back to Top

Protein Sequence Length: 1115 aa Download sequence Send to blast

MSIIMTHSRL VVLWFAHDNI AQILLEAKHR WLRPAEICEI LQNYQKFQIA SVPANKPPGG  60
SLFLFDRKVL RYFRKDGHNW RKKKDGKTVK EAHERLKAGS VDVLHCYYAH GEENENFQRR  120
SYWMLEEALQ HIVLVHYREV KGNRTNYNHI KGTEEGVPYS HETEEVALNS EMDNSVSSSF  180
NPSSFQMRSQ ATDATSLSSA QASEFEDAES VYNHQASSQL QPFLELLQPK AEKTNAGVST  240
AFYPMSFSDE YQEKLSAIPG VNFSSHTQAY RKEDVKDAGV TYDPRRNLNS TLCDGALGNI  300
TTGFQSLPFQ PSISATHSDS TGIISKQENE TFGHLFTNNF GKKQMYEDRP RVQQSWQQTL  360
EANSSGSSSG PVDQNLHSNT AYDVSTRFHE GVDASNLLNS LVCHVDSDKT NDYSMPNDLQ  420
IQPSNPEQEC HLKSISKRNE TIEGSNNHAF ATRPLLDEGL KKLDSFNRWM SKELGDVDET  480
QTQSNSETYW DTVESENGVD ESSVPLHVRL DSYMLGPSLS QDQLFSIIDF SPNWAYENSE  540
IKVLITGRFL KSQEAKSCKW SCMFGEVEVP AEVIADGVLR CYTPIHKAGR IPFYVTCSNR  600
LACSEIREFE YRVGQIPDYD AKDDYSGCMN EILNMRFGKL LSLSSSSPTF DPTSIAENSE  660
LISKIDLLLK NDNGEWDRML QLTSDEDFSL ERVEDQLLQQ LLKEKLHAWL LQKLAAGGKG  720
PSVLDEGGQG VLHFGAALGY DWVLLPTITA GVSVNFRDVN GWTALHWAAF HGRERTVASL  780
ISLGAAPGLL TDPRTKYPAG RTPADLASAR GHKGIAGYLA ESALSDHLSF LNLDVKEGNN  840
AEISGAKAVE TASERIATPI RNGDLTGGLS LRDSLTAVCN ATQAAARIHQ VLRVKSFQRK  900
QLKEYGSDNF GISDEDALSL IAVKSHKPGK RDEHVDAAAI RIQNKFRSWK GRKDYLIIRQ  960
RIVKLQAHVR GHQVRKNYRK IVWSVGIVEK IILRWRRKGS GLRGFKPEAL AEPPSMQASS  1020
SKDDDYDVLK EGRKQTEQRL QKALARVKSM VRYPEARDQY SRLLNVVTEI QETKVVYDSI  1080
MNSSDGRADM DDDLVDFAAL LDEDDVCMPT AAPE*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2cxk_A	7e-15	527	614	9	91	calmodulin binding transcription activator 1
2cxk_B	7e-15	527	614	9	91	calmodulin binding transcription activator 1
2cxk_C	7e-15	527	614	9	91	calmodulin binding transcription activator 1
2cxk_D	7e-15	527	614	9	91	calmodulin binding transcription activator 1
2cxk_E	7e-15	527	614	9	91	calmodulin binding transcription activator 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr028900.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018498818.1	0.0	PREDICTED: calmodulin-binding transcription activator 3-like isoform X1
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A498HVW2	0.0	A0A498HVW2_MALDO; Uncharacterized protein
STRING	XP_009338097.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8284	27	35

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]