PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pbr027424.1
Organism
Pyrus bretschneideri
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus
Family bHLH
Protein Properties Length: 610aa    MW: 67349.6 Da    PI: 6.6376
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pbr027424.1genomeCPETRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH38.71.8e-12440486455
                  HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                  +h e+Er+RR ++N++f  Lr ++P+ +      K++Ka+ L  A+ YI++Lq
  Pbr027424.1 440 NHVEAERQRRGKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYINELQ 486
                  799***********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.0E-5149237IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.539436485IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000837.62E-14439490No hitNo description
SuperFamilySSF474596.67E-18439500IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000105.3E-10440486IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.108.0E-18440499IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.0E-15442491IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 610 aa     Download sequence    Send to blast
MGLGGGVWDD EDKAMVAQVL GTRAFDYLIS SAVSSNENSF MGIGTDENLH NKLSDLVERP  60
NASNFSWNYA IFWQISRSKS GDWVLCWGDG SCREPKEGEV SETTRILGLR LDDGTQQRMR  120
KIVLQKLHNL FGSSDEYNGA LGLDRVTDME MFLLASMYFS FPRGEEGPGK CFASGEHVWL  180
LDLLKSGSEY CVRSFLAKSA GIQTIVLVPT DVGVVELGSV RCIGERLELL QSIRSLFSTQ  240
SSHMRAKPVA GVPMIGRRRD ENVHLTNLSP VERGEAVPKI FGQDLNSGNS VRPRYREKLA  300
VRKLEERPWD VYSNGNRIAF SSPRNGIHGS NWPHNHDVKQ GSATEMYASQ SPVNNLQELV  360
DGVRDDFRHN HYQPQKQVPM QMDFSGATSR PSVAPRPIGV DSENSDAEAP CKEDQPGTAD  420
ERRPRKRGRK PANGREEPLN HVEAERQRRG KLNQRFYALR AVVPNISKMD KASLLGDAIA  480
YINELQAKLK VMEAERENLG GTSRDASALG ASSGMEIQNQ APEVDIQAVN DEVIVRVSSP  540
LDSHPASRVV EAFKEAQITV VESKLAAADD TVLHTFVVKS QGSERLTKEK LIAAFSRESN  600
SLHSLSSVG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A9e-29434527277Transcription factor MYC2
5gnj_B9e-29434527277Transcription factor MYC2
5gnj_E9e-29434527277Transcription factor MYC2
5gnj_F9e-29434527277Transcription factor MYC2
5gnj_G9e-29434527277Transcription factor MYC2
5gnj_I9e-29434527277Transcription factor MYC2
5gnj_M9e-29434527277Transcription factor MYC2
5gnj_N9e-29434527277Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1421429RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapPbr027424.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMap-Retrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKR2598480.0KR259848.1 Prunus avium cultivar Tieton bHLH transcription factor (bHLH13) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018498541.10.0PREDICTED: transcription factor bHLH13 isoform X1
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A498KJT30.0A0A498KJT3_MALDO; Uncharacterized protein
STRINGXP_009336761.10.0(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF54483254
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]