PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

ERF

Protein Properties

Length: 251aa MW: 27658.3 Da PI: 7.6663

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr018333.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	63.2	5.5e-20	55	104	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+W+AeIrdp+ + +r++lg+f tae+Aa a+++a+++++g Pbr018333.1 55 HYRGVRQRP-WGKWAAEIRDPK----KaARVWLGTFETAEDAAIAYDNAALRFKG 104 7******.******94....45*********************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.730.10	8.4E-33	54	113	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	24.619	55	112	IPR001471	AP2/ERF domain
SMART	SM00380	3.4E-38	55	118	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	3.86E-22	55	113	IPR016177	DNA-binding domain
CDD	cd00018	3.03E-32	55	113	No hit	No description
Pfam	PF00847	1.2E-12	55	104	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.2E-11	56	67	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.2E-11	78	94	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 251 aa Download sequence Send to blast
MSAMVSALTQ VIGTTEGHAA VQPNPTSISD SSPLVKQEPD RSEPVQDQET VRRRHYRGVR 60 QRPWGKWAAE IRDPKKAARV WLGTFETAED AAIAYDNAAL RFKGTKAKLN FPERVQGKTD 120 FGILMGSSGT TTNSSSGAAS TQRTQNLMRP AGRIVNPQTA PAPLITSQQP ETFPDLYQYA 180 QLLSSNDADF CNYSFYPFNQ DPRFTSQFSP SSTNLSSSTA SHDSQPSQQR RQDHEEDAGN 240 KDWNSSNPRE *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	3e-28	54	115	4	66	ATERF1
3gcc_A	3e-28	54	115	4	66	ATERF1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in the regulation of plant development and tolerance to abiotic stresses (PubMed:21069430). Acts as positive regulator of tolerance to waterlogging stress. Delays waterlogging-induced premature senescence by regulating stomatal closure and antioxidant enzyme activity. May function through ABI1-mediated abscisic acid (ABA) signaling pathway (PubMed:22661072). Involved in tissue reunion of wounded inflorescence stems. Required for the division of pith cells in the reunion process, which is dependent on polar-transported auxin and the wound-inducible hormones ethylene and jasmonate (PubMed:21911380). Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:21069430, ECO:0000269\|PubMed:21911380, ECO:0000269\|PubMed:22661072}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr018333.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by salt stress (PubMed:16133218, PubMed:21069430). Induced drought stress, jasmonate (JA), salicylic acid (SA), abscisic acid (ABA) and ethylene. Down-regulated by freezing stress (PubMed:21069430). Induced by wounding in the flowering stem (PubMed:21911380). Induced by waterlogging. {ECO:0000269\|PubMed:16133218, ECO:0000269\|PubMed:21069430, ECO:0000269\|PubMed:21911380}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	GU732450	0.0	GU732450.1 Malus x domestica AP2 domain class transcription factor (AP2D26) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009353514.1	0.0	PREDICTED: ethylene-responsive transcription factor ERF113-like
Refseq	XP_009378798.1	0.0	PREDICTED: ethylene-responsive transcription factor ERF113-like
Swissprot	Q9LYU3	1e-49	EF113_ARATH; Ethylene-responsive transcription factor ERF113
TrEMBL	A0A4D5XED2	0.0	A0A4D5XED2_9ROSA; Ethylene Responsive Factor ERF113
STRING	XP_009353514.1	0.0	(Pyrus x bretschneideri)
STRING	XP_009378798.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF985	34	115

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G61890.1	1e-30	ERF family protein

Publications ? help Back to Top
Huang Z,Zhao P,Medina J,Meilan R,Woeste K Roles of JnRAP2.6-like from the transition zone of black walnut in hormone signaling. PLoS ONE, 2013. 8(11): p. e75857 [PMID:24265672] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Asahina M,Satoh S Molecular and physiological mechanisms regulating tissue reunion in incised plant tissues. J. Plant Res., 2015. 128(3): p. 381-8 [PMID:25736731] Hickman R, et al. Architecture and Dynamics of the Jasmonic Acid Gene Regulatory Network. Plant Cell, 2017. 29(9): p. 2086-2105 [PMID:28827376] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Matsuoka K, et al. RAP2.6L and jasmonic acid-responsive genes are expressed upon Arabidopsis hypocotyl grafting but are not needed for cell proliferation related to healing. Plant Mol. Biol., 2018. 96(6): p. 531-542 [PMID:29344830] Yang S,Poretska O,Sieberer T ALTERED MERISTEM PROGRAM1 Restricts Shoot Meristem Proliferation and Regeneration by Limiting HD-ZIP III-Mediated Expression of RAP2.6L. Plant Physiol., 2018. 177(4): p. 1580-1594 [PMID:29884678]