PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

ERF

Protein Properties

Length: 321aa MW: 35112.9 Da PI: 7.4709

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr016912.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	55.7	1.2e-17	42	92	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s++ GVr+++ +grWvAeI+d + ++ r +lg+f taeeAa+ +++a+ l+g Pbr016912.1 42 SKFVGVRQRP-SGRWVAEIKDTT---QKIRMWLGTFETAEEAARSYDEAACLLRG 92 79******.7*****32...35********************99987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	3.0E-12	42	92	IPR001471	AP2/ERF domain
CDD	cd00018	5.63E-32	42	99	No hit	No description
SuperFamily	SSF54171	1.05E-18	42	100	IPR016177	DNA-binding domain
SMART	SM00380	3.4E-35	43	106	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.7E-27	43	100	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	19.493	43	100	IPR001471	AP2/ERF domain
PRINTS	PR00367	3.9E-7	44	55	IPR001471	AP2/ERF domain
PRINTS	PR00367	3.9E-7	66	82	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 321 aa Download sequence Send to blast
MEFQFQQPKQ VSFAAACIPK SSSKVGKWKG RNNNRRSNNK ASKFVGVRQR PSGRWVAEIK 60 DTTQKIRMWL GTFETAEEAA RSYDEAACLL RGSNARTNFI THVSLDSPLA SRIRNLLNTK 120 KGGGGATKQL ALLHHQSSST STTTSASSDH DHLPPPSKQL VRKSSTCTST SSGSDTTSLS 180 SEVFQDNSLL FDNVYKPDLR NCNEDFELSS SSNTSQSDLP SWVSYQTGVD CFSFAQQAFE 240 FPKHQAAAAL SSAESNTTTT STISTAGEAD SGLTDFERLK VERQISASLY AMNGMQEYME 300 TVHDPNEALW DLPPLCSLFC *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	4e-14	42	109	13	81	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the symbiotic nodule signaling pathway in response to rhizobial stimulation. Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation, and nodule development. May coordinate these processes (PubMed:28503742, PubMed:28028038, PubMed:28068194). Functions downstream of the CCAMK-CYCLOPS complex (PubMed:28503742, PubMed:28028038). Probably not involved in arbuscular mycorrhizal (AM) symbiosis (PubMed:28068194). {ECO:0000269\|PubMed:28028038, ECO:0000269\|PubMed:28068194, ECO:0000269\|PubMed:28503742}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr016912.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in nodules 7 days after rhizobial inoculation. {ECO:0000269\|PubMed:28028038, ECO:0000269\|PubMed:28503742}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009353193.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-11-like
Swissprot	A0A1X9PY88	8e-94	ERN1_LOTJA; Ethylene-responsive transcription factor ERN1
TrEMBL	A0A498I1J3	1e-163	A0A498I1J3_MALDO; Uncharacterized protein
STRING	XP_009353193.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3341	30	69

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G19790.1	2e-38	related to AP2 11

Publications ? help Back to Top
Yano K, et al. Function and evolution of a Lotus japonicus AP2/ERF family transcription factor that is required for development of infection threads. DNA Res., 2017. 24(2): p. 193-203 [PMID:28028038] Kawaharada Y,James EK,Kelly S,Sandal N,Stougaard J The Ethylene Responsive Factor Required for Nodulation 1 (ERN1) Transcription Factor Is Required for Infection-Thread Formation in Lotus japonicus. Mol. Plant Microbe Interact., 2017. 30(3): p. 194-204 [PMID:28068194] Cerri MR, et al. The ERN1 transcription factor gene is a target of the CCaMK/CYCLOPS complex and controls rhizobial infection in Lotus japonicus. New Phytol., 2017. 215(1): p. 323-337 [PMID:28503742]