PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

ERF

Protein Properties

Length: 252aa MW: 28351.7 Da PI: 6.3116

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr011102.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	55.9	1e-17	106	155	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 y+GVr+++ +g+++AeIrd + + r++lg+f++ae Aa a+++a+ +l+g Pbr011102.1 106 YRGVRRRP-WGKYAAEIRDSTR---HgIRVWLGTFDSAEAAALAYDQAAFALRG 155 9*****.******422...25***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00380	2.6E-36	105	169	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	23.103	105	163	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	3.33E-22	105	164	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	3.4E-29	105	164	IPR001471	AP2/ERF domain
CDD	cd00018	6.90E-21	106	165	No hit	No description
Pfam	PF00847	1.2E-12	106	155	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.6E-10	106	117	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.6E-10	129	145	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 252 aa Download sequence Send to blast
MEMESAFFHF SSPDFSSDSS FGSLHSFSWG DESLLLPFNS HELMNFPPFN INDSQDMLLY 60 DVVARGAKQT LVAQNEANSF NGVKEQEVTS ANNQTLEEKS TKEKAYRGVR RRPWGKYAAE 120 IRDSTRHGIR VWLGTFDSAE AAALAYDQAA FALRGSLAVL NFPAQVVQDS LQEIKYRHDE 180 ACSPVIALKR RHSMKRKSMH KKGNKPSQCT DQRKVQEVLP QNVMVLEDLG VEYLEELLDI 240 SSCGSNHWSP Q*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	1e-27	106	163	15	72	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr011102.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009369492.1	0.0	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	7e-69	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A498IVL4	1e-155	A0A498IVL4_MALDO; Uncharacterized protein
STRING	XP_009369492.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF311	33	199

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	5e-56	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]