PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pbr008477.1
Organism
Pyrus bretschneideri
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus
Family HD-ZIP
Protein Properties Length: 1038aa    MW: 114045 Da    PI: 6.2916
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pbr008477.1genomeCPETRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.74.6e-19345399256
                  T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
     Homeobox   2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                  +k +++t+eq+++Lee+F+ + +p+ ++r++L ++lgL+ +q+k+WFqN+R++ k
  Pbr008477.1 345 KKYHRHTNEQIQRLEEFFKHCAHPDDSQRQQLGRELGLEPKQIKFWFQNKRTQTK 399
                  78999**********************************************9987 PP
2START1433e-455497712206
                  HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEEEEC CS
        START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv.....dsgealrasgvvdmvlallveellddkeqWdetla....kaetlevis 86 
                  +a +a++elvk+ + +ep+Wvks       +n+  + ++f++++       ++e +++sgvv+  +a+lv  +ld++ +W e ++    ka+t+ev++
  Pbr008477.1 549 IAASALEELVKLFQIDEPLWVKSTaygrYFLNRGNYDKIFPRTNQfktssARIESSKDSGVVTISAATLVDMFLDSS-KWEELFPtivtKAKTIEVLE 645
                  678899******************999988899999999988877899999**************************.******99999********* PP

                  TT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXX CS
        START  87 sg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvdlkgrlp 177
                  sg      g l lm+ ++  lsplv  Rdf+f+Ry++q + g+wvivdvS   +++   ss+  R+ +lpSg+lie++ ng skvtw+ehv++++++ 
  Pbr008477.1 646 SGmignrsGCLLLMYEQMHILSPLVLpRDFYFLRYCQQIKLGTWVIVDVSHKFPKES--SSNQSRSWRLPSGCLIEDMTNGCSKVTWIEHVEVDDKTQ 741
                  ************************966*********************888887775..6899999*****************************999 PP

                  .HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
        START 178 .hwllrslvksglaegaktwvatlqrqcek 206
                   h l+r l+ s++a ga +w  tl+r ce+
  Pbr008477.1 742 tHRLYRDLICSSVAYGAERWIITLKRMCER 771
                  8***************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR020126.9E-11631324IPR013765DNA recombination and repair protein RecA
SuperFamilySSF525401.83E-4032266IPR027417P-loop containing nucleoside triphosphate hydrolase
PfamPF001547.5E-9234253IPR013765DNA recombination and repair protein RecA
PROSITE profilePS5016223.15662214IPR020588DNA recombination and repair protein RecA-like, ATP-binding domain
Gene3DG3DSA:3.40.50.3001.1E-4863269IPR027417P-loop containing nucleoside triphosphate hydrolase
SMARTSM003822.2E-683247IPR003593AAA+ ATPase domain
PRINTSPR001424.4E-52119148IPR013765DNA recombination and repair protein RecA
PRINTSPR001424.4E-52153182IPR013765DNA recombination and repair protein RecA
PRINTSPR001424.4E-52191220IPR013765DNA recombination and repair protein RecA
PROSITE profilePS5016318.23218274IPR020587DNA recombination and repair protein RecA, monomer-monomer interface
PRINTSPR001424.4E-52229257IPR013765DNA recombination and repair protein RecA
PROSITE patternPS003210232240IPR020584DNA recombination/repair protein RecA, conserved site
SuperFamilySSF547521.7E-15271323IPR023400DNA recombination and repair protein RecA, C-terminal
Gene3DG3DSA:3.30.250.101.4E-19271324IPR023400DNA recombination and repair protein RecA, C-terminal
PRINTSPR001424.4E-52299316IPR013765DNA recombination and repair protein RecA
Gene3DG3DSA:1.10.10.602.7E-20332403IPR009057Homeodomain-like
SuperFamilySSF466891.55E-17333401IPR009057Homeodomain-like
PROSITE profilePS5007116.633341401IPR001356Homeobox domain
SMARTSM003891.0E-16343405IPR001356Homeobox domain
CDDcd000863.08E-17345402No hitNo description
PfamPF000461.2E-16345399IPR001356Homeobox domain
PROSITE profilePS5084846.754539774IPR002913START domain
SuperFamilySSF559614.4E-32540772No hitNo description
CDDcd088753.89E-103543770No hitNo description
SMARTSM002344.4E-33548771IPR002913START domain
PfamPF018521.2E-37549771IPR002913START domain
Gene3DG3DSA:3.30.530.204.9E-9604735IPR023393START-like domain
SuperFamilySSF559618.1E-157991000No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006281Biological ProcessDNA repair
GO:0003697Molecular Functionsingle-stranded DNA binding
GO:0005524Molecular FunctionATP binding
GO:0008094Molecular FunctionDNA-dependent ATPase activity
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 1038 aa     Download sequence    Send to blast
MAVKPIKRVR CELQAKVNGA LSADSDPRFV DRQKALEAAM NDINSSFGKG SVTRLGSAGG  60
ALVETFPSGC LTLDLALGGG LPKGRIVEIF GPESSGKTTL ALHAIAEVQK LGGNAMLVDA  120
EHAFDPAYSR ALGVDVENLI VCQPDHGEMA LEIADRMCRS GAIDLICVDS VSALTPRAEI  180
EGEIGMQQMG LQARLMSQAL RKISLPETNS LTPCCKIGVY YGNPEVTSGG IALKFFASVR  240
LEIRSTGKIK SVSRPYKQAE FEIVFGEGVG KLGCILDCAE AMDVVVRKGS WYSYGDHRLG  300
QGRDKALQYL RENPLLLDEM EKRMELLGNG GASSDEASNS RRGNKKYHRH TNEQIQRLEE  360
FFKHCAHPDD SQRQQLGREL GLEPKQIKFW FQNKRTQTKA QSERADNTIL RQDNERIQCE  420
NYAMREALKN VSCPTCGGPP FGEEERQINL QSLQLENAYL KEEASIWNIN KISSHDKVAS  480
LLSKYIGKPL SQIESLASVV GSTLDLSPGC SINQGIIGSP PLDLNLTSPA FSYQLQEIPE  540
MEKALMADIA ASALEELVKL FQIDEPLWVK STAYGRYFLN RGNYDKIFPR TNQFKTSSAR  600
IESSKDSGVV TISAATLVDM FLDSSKWEEL FPTIVTKAKT IEVLESGMIG NRSGCLLLMY  660
EQMHILSPLV LPRDFYFLRY CQQIKLGTWV IVDVSHKFPK ESSSNQSRSW RLPSGCLIED  720
MTNGCSKVTW IEHVEVDDKT QTHRLYRDLI CSSVAYGAER WIITLKRMCE RFDCLMDEVE  780
STCEFGGGKS SLIPMVTSPE GKRSVMKLSQ RMVKNFCGML SMAVKLDFPQ LSEVNNSGVR  840
VSVRKSAESG QPHGMIVSVA TSLWLPLPSE TVFNFFRDEK NRVQWDVLSN GNPVHEIANI  900
STGTHPGNCV SVIRPFIPTE NNMLMLQESY TDPLGSLFVY APVDVPALNV AVSGEDSSNI  960
PILPSGFVIS GDGRAEVTGD SGHSTAGGSL LTVAFQILVS SPSTSKQMNM ESVATVNTLI  1020
SSTVQKIKVA LNCSSLD*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubc_A1e-101313397341RecA
1ube_A1e-101313397341RecA
1ubf_A1e-101313397341RecA
1ubg_A1e-101313397341RecA
2g88_A1e-101313397341Protein recA
2odn_A1e-101313397341Protein recA
2odw_A1e-101313397341Protein recA
2oe2_A1e-101313397341Protein recA
2oep_A1e-101313397341Protein recA
2oes_A1e-101313397341Protein recA
2ofo_A1e-101313397341Protein recA
2zr0_A1e-101313397341Protein recA
2zr7_A1e-101313397341Protein recA
2zr9_A1e-101313397341Protein recA
2zra_A1e-101313397341Protein recA
2zrb_A1e-101313397341Protein recA
2zrm_A1e-101313397341Protein recA
2zrn_A1e-101313397341Protein recA
2zro_A1e-101313397341Protein recA
2zrp_A1e-101313397341Protein recA
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPbr008477.1
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009367126.10.0PREDICTED: homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A251PUX60.0A0A251PUX6_PRUPE; Uncharacterized protein
STRINGXP_009367126.10.0(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF10263398
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]