PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

MYB

Protein Properties

Length: 240aa MW: 27392.8 Da PI: 8.2094

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr000261.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	43.6	7e-14	16	63	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+W++eEd++lv +++++G +W+ ++ g+ R++k+c++rw +yl Pbr000261.1 16 KGPWSPEEDQKLVVYIQRYGIWNWSQMPEPAGLARSGKSCRLRWVNYL 63 79****************99**********************97 PP
2	Myb_DNA-binding	53.7	4.9e-17	69	114	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+++++E+e ++++++ G++ W++Ia++++ gRt++++k++w +++ Pbr000261.1 69 RGNFSKDEEETILELHQAIGNR-WSAIAARLP-GRTDNEIKNHWKTHM 114 89******************.*****.*********9986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	10.979	11	63	IPR017930	Myb domain
SuperFamily	SSF46689	2.59E-30	14	110	IPR009057	Homeodomain-like
SMART	SM00717	3.2E-9	15	65	IPR001005	SANT/Myb domain
Pfam	PF00249	1.5E-12	16	63	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	7.3E-23	17	70	IPR009057	Homeodomain-like
CDD	cd00167	1.84E-7	18	63	No hit	No description
PROSITE profile	PS51294	24.226	64	118	IPR017930	Myb domain
SMART	SM00717	4.9E-16	68	116	IPR001005	SANT/Myb domain
Pfam	PF00249	1.3E-15	69	113	IPR001005	SANT/Myb domain
CDD	cd00167	4.14E-10	71	114	No hit	No description
Gene3D	G3DSA:1.10.10.60	3.2E-26	71	117	IPR009057	Homeodomain-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 240 aa Download sequence Send to blast
MAKRTQRCEK TVAMKKGPWS PEEDQKLVVY IQRYGIWNWS QMPEPAGLAR SGKSCRLRWV 60 NYLRPDIKRG NFSKDEEETI LELHQAIGNR WSAIAARLPG RTDNEIKNHW KTHMKKRFKA 120 AIESLHEEAK GFGDKEASKN KLSETEQLFL VDEDTRASSS KMETTSSTSA PSRLFCPVWE 180 FDDRKGQIAE QSICASGVTF GDLQSLDSQV WQQEPIFPCD SYINHATSDY WVSLINKTG*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	2e-28	14	118	5	108	B-MYB
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in cold stress response (PubMed:14675437, PubMed:20807373, PubMed:22246661). Regulates positively the expression of genes involved in reactive oxygen species (ROS) scavenging such as peroxidase and superoxide dismutase during cold stress. Transactivates a complex gene network that have major effects on stress tolerance and panicle development (PubMed:20807373). {ECO:0000269\|PubMed:14675437, ECO:0000269\|PubMed:20807373, ECO:0000269\|PubMed:22246661}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr000261.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cold stress. {ECO:0000269\|PubMed:14675437, ECO:0000269\|PubMed:20807373, ECO:0000269\|Ref.2}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	DQ074469	0.0	DQ074469.1 Malus x domestica MYB21 mRNA, complete cds.
GenBank	KC691248	0.0	KC691248.1 Malus x domestica MYB transcription factor mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009373022.1	0.0	PREDICTED: myb-related protein Myb4-like
Swissprot	Q7XBH4	8e-57	MYB4_ORYSJ; Transcription factor MYB4
TrEMBL	Q2LME3	1e-151	Q2LME3_MALDO; MYB transcription factor
STRING	XP_009373022.1	1e-180	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF356	33	186

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G05100.1	4e-55	myb domain protein 74

Publications ? help Back to Top
Park MR, et al. Supra-optimal expression of the cold-regulated OsMyb4 transcription factor in transgenic rice changes the complexity of transcriptional network with major effects on stress tolerance and panicle development. Plant Cell Environ., 2010. 33(12): p. 2209-30 [PMID:20807373] Soltész A, et al. The rice Osmyb4 gene enhances tolerance to frost and improves germination under unfavourable conditions in transgenic barley plants. J. Appl. Genet., 2012. 53(2): p. 133-43 [PMID:22246661]