PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Panicinae; Panicum

Family

C2H2

Protein Properties

Length: 523aa MW: 55068.1 Da PI: 8.1143

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pahal.C03978.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.3	2.7e-05	103	125	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Pahal.C03978.1 103 FVCEICHKGFQRDQNLQLHRRGH 125 89*******************88 PP
2	zf-C2H2	12.3	0.00051	216	234	5	23
TTTEEESSHHHHHHHHHHT CS zf-C2H2 5 dCgksFsrksnLkrHirtH 23 dCg++Fsr++++++H + Pahal.C03978.1 216 DCGTVFSRRDSFVTHRAFC 234 9**************8765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.14E-5	102	125	No hit	No description
Gene3D	G3DSA:3.30.160.60	7.9E-5	102	125	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.637	103	125	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	105	125	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	9.0E-4	174	206	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.14E-5	181	206	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 523 aa Download sequence Send to blast
MSGAAARECA GSFSSVSSNN TASREVEEEF LQHQQRQFHI KPLLGSPPEM GTDDGDLQRV 60 TGPSEPPPAA PTVKKKRSLP GTPDPSAEVI ALSPRTLMAT NRFVCEICHK GFQRDQNLQL 120 HRRGHNLPWK LRQRGGGADA AGGGPPRKRV YVCPEASCVH HNPGRALGDL TGIKKHYCRK 180 HGEKKWKCER CAKRYAVHSD WKAHAKVCGT REYKCDCGTV FSRRDSFVTH RAFCDALAQE 240 NNKLAQPMNM ATVASALQGQ AHRLAFPQSH QEADDLDAAE DEDADDFALD TKSPQLRMLP 300 AAMPDDAAAP LLPPLSMAGC MLSSLAAARP APSPSTAFFT GARIGLDGPS DPNRSMGGGF 360 SPAGSATASM SATALLQKAA EMGATTGGGY GAGFATVGFG PMLGGPNHVP TMSPFGPLKA 420 PTMDPPYDGL PLGPAQLVGL DAGRLLPGQL YCGSNGGGAH GGGVGSMTRA IGSLMHGGQQ 480 QQTTEHRRPD DLRVVDYLGV DDQRSFSGGG VSPFGPHIGP WA*

Sequence ? help Back to Top

Protein Sequence Length: 523 aa Download sequence Send to blast

MSGAAARECA GSFSSVSSNN TASREVEEEF LQHQQRQFHI KPLLGSPPEM GTDDGDLQRV  60
TGPSEPPPAA PTVKKKRSLP GTPDPSAEVI ALSPRTLMAT NRFVCEICHK GFQRDQNLQL  120
HRRGHNLPWK LRQRGGGADA AGGGPPRKRV YVCPEASCVH HNPGRALGDL TGIKKHYCRK  180
HGEKKWKCER CAKRYAVHSD WKAHAKVCGT REYKCDCGTV FSRRDSFVTH RAFCDALAQE  240
NNKLAQPMNM ATVASALQGQ AHRLAFPQSH QEADDLDAAE DEDADDFALD TKSPQLRMLP  300
AAMPDDAAAP LLPPLSMAGC MLSSLAAARP APSPSTAFFT GARIGLDGPS DPNRSMGGGF  360
SPAGSATASM SATALLQKAA EMGATTGGGY GAGFATVGFG PMLGGPNHVP TMSPFGPLKA  420
PTMDPPYDGL PLGPAQLVGL DAGRLLPGQL YCGSNGGGAH GGGVGSMTRA IGSLMHGGQQ  480
QQTTEHRRPD DLRVVDYLGV DDQRSFSGGG VSPFGPHIGP WA*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	4e-33	182	249	3	70	Zinc finger protein JACKDAW
5b3h_F	4e-33	182	249	3	70	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT066652	0.0	BT066652.1 Zea mays full-length cDNA clone ZM_BFb0043G06 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_025817951.1	0.0	protein indeterminate-domain 2-like
Swissprot	Q9SCQ6	1e-104	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A2S3HNI1	0.0	A0A2S3HNI1_9POAL; Uncharacterized protein
STRING	Sb03g045120.1	0.0	(Sorghum bicolor)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP12554	25	34

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G03840.1	1e-101	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Pahal.C03978.1

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]